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Displaying studies 1 - 25 of 30 in total


A Study for Those with Hip Pain from GTPS

Official Title: Load modification versus standard exercise to inform treatment for individuals with greater trochanteric pain syndrome

The purpose of this study is to compare the effects of two different physical therapy programs on pain and function in individuals diagnosed with greater trochanteric pain syndrome (GTPS) (also known as lateral hip pain).

A study on post surgical pain management

Official Title: A multicenter, prospective, active controlled, real world, Phase 4 study of EXPAREL in multimodal regimens compared with standard of care for postsurgical pain management in subjects undergoing lumbar posterior spine surgeries (FUSION)

The main purpose of this study is to compare total opioid consumption by patients in different treatment groups. Another purpose of this study is to assess how well the study drug called EXPAREL is in reducing pain compared with current available standard of care treatments in adults undergoing l...

A study for those undergoing MLF Surgery

Official Title: SIJ Stabilization in Long Fusion to the Pelvis: Randomized Controlled Trial

To determine whether placement of iFuse-3D across the ssacroiliac joint (SIJ) in the Bedrock configuration provides clinical and/or radiographic benefits in patients undergoing multilevel spine fusion (MLF) surgery with fixation to the pelvis

A Study on Joint Laxity

Official Title: The Influence of Joint Hypermobility on Physical Function and Biomechanics in Healthy Adolescents

The purpose of this study is to determine if joint mobility, particularly joint hypermobility or laxity, affects pain, physical function and biomechanics and healthy adolescents without an underlying rheumatologic disease.

The Effects of Dry Needling on Knee Pain

Official Title: The Effects of Dry Needling on Patients with Knee Pain

This study is testing the effectiveness of "dry needling" for pain management and on muscle strength and leg function for those with knee pain. Dry needling consists of small, monofilament needles that are administered directly into the tissue and manipulated to make the muscle relax for pain relief...

A Study Using the Calypso Knee System

Official Title: Evaluation of the Calypso Knee System for Symptom Relief in Subjects with Medial Knee Osteoarthritis

The purpose of this study is to evaluate the results of the Calypso Knee System when used to treat symptomatic osteoarthritis of the medial compartment of the knee. This study will examine how safe and effectively the Calypso Knee System performs in reducing or eliminating knee pain and increasing k...

A treatment study for chondral lesion in your knee

Official Title: Evaluation of the efficacy of radiofrequency-based debridement vs. mechanical debridement for the treatment of articular cartilage lesions.

The purpose of this study is to evaluate 2 different treatments, Mechanical Debridement (i.e., a mechanical shaver that removes areas of damaged tissue) and Radiofrequency Debridement (i.e., electrical energy that removes areas of damaged tissue), used to treat the chondral lesion in your knee.

A Study About Recovery After ACL Reconstruction (RARE)

Official Title: Disability after ACL Reconstruction: Development of an Alternative Model of Care

The anterior cruciate ligament (ACL) in your knee can be injured and treated with an ACL reconstruction surgery. An ACL reconstruction may impact function, muscle strength, the way you move, and knee joint health. However, outcomes at 2 years after ACL reconstructions in young persons are not well-...

Stability and Control of Amputee-Walking

Official Title: Human locomotion phenomenology: data collection in many locomotor situations toward informing a more complete theory of locomotion

Our goal is to collect information on how people walk and run in a variety of different circumstances and speeds. We want to understand how people change the way they walk or run depending on the situation. Our proposed research aims to examine dynamic stability and control strategies of amputees...

Stability and Control of Walking and Running

Official Title: Human locomotion phenomenology: data collection in many locomotor situations toward informing a more complete theory of locomotion

Our goal is to collect information on how people walk and run in a variety of different circumstances and speeds. We want to understand how people change the way they walk or run depending on the situation. Participants will be asked to perform simple walking and running tasks on a treadmill or o...

A Treatment Study for Subchondroplasty® Procedure in the Hip

Official Title: A Longitudinal Outcomes Study of the Subchondroplasty® Procedure in the Hip

To collect outcomes data for patients undergoing the Subchondroplasty® (SCP®) Procedure in the hip. Outcomes to be assessed include medication usage, pain, function, activity levels and patient satisfaction.

A Treatment Study of Joint Surface Lesions of the Knee -- Agili-C™ vs. Surgical Standard of Care

Official Title: A Prospective Multicenter Open-label Randomized Controlled Trial of Agili-C™ vs. Surgical Standard of Care (SSOC) for the Treatment of Joint Surface Lesions of the Knee

To compare the effectiveness and safety of the Agili-CTM implant to Surgical Standard of Care (SSOC) treatment in patients suffering from joint surface lesions of the knee.

A Treatment Study for Damaged Knee Cartilage Requiring Repair-- Hyalofast with BMAC

Official Title: A prospective, randomized, active treatment-controlled, evaluator-blinded (radiologist reviewer and physician evaluator) multicenter study to establish the superiority of a hyaluronan-based scaffold (Hyalofast®) with autologous bone marrow aspirate concentrate (BMAC) in the treatment of articular knee cartilage defect lesions in comparison to control (microfracture treatment)

The purpose of this research study is to evaluate an investigational procedure for treatment of damage to the cartilage in your knee, also called a defect or lesion, which requires repair. If eligible, you will receive one of two possible arthoscophy procedures. You may be assigned to receive the st...

Registry for Shoulder Surgery Outcomes

Official Title: Shoulder Surgery Outcomes Registry

This registry will collect outcomes data of patients undergoing shoulder surgery with Dr. Jonathan Barlow or Dr. Julie Bishop. The purpose of this registry is to provide a way to collect and store data for patients undergoing shoulder surgery to support the conduct of future research in an effort t...

Follow-up Study for Those Who Have Undergone (or Will Undergo) the Subchondroplasty (SCP) Knee Procedure

Official Title: KNEE CREATIONS SCP® OBSERVATIONAL COHORT FOLLOW-UP STUDY

A study for those who will (have undergone) the Subchondroplasty (SCP) procedure for their knee. SCP is a procedure performed on subjects who have bone marrow lesions(BMLs). BMLs are subchondral defects in the bone, also called Insufficiency Fractures. This follow-up study will collect information...

Rotator Cuff Study--For Those Who Require Surgical Treatment for Full Thickness Massive Tear

Official Title: A prospective, single blinded, multi-center, randomized, controlled, pivotal study to assess the safety and effectiveness of the InSpace™ device for treatment of full thickness Massive Rotator Cuff Tears

This research study will evaluate a new device, InSpace, for use with a full thickness massive tear of rotator cuff (the group of connective tissues in the shoulder). The device is designed to allow smooth gliding of the bones in the shoulder during motion, which may allow rehabilitation exercises ...

A Treatment Study for Single Articular Cartilage Lesion of the Knee--NOVOCART®3D (N3D)

Official Title: A Phase 3 Prospective, Randomized, Partially Blinded Multi-Center Study to Measure the Safety and Efficacy of NOVOCART® 3D, Compared to Microfracture in the Treatment of Articular Cartilage Defects

The purpose of this research study is to evaluate an investigational procedure for treatment of knee cartilage defects. If eligible, you will receive one of two possible surgical procedures. One is the investigational procedure under study, utilizes the Novocart® 3D autologous cartilage implant sy...

A Registry for Those with Hypophosphatasia (HPP)

Official Title: AN OBSERVATIONAL, LONGITUDINAL, PROSPECTIVE, LONG-TERM REGISTRY OF PATIENTS WITH HYPOPHOSPHATASIA

The purpose of this registry is to collect information about Hypophosphatasia (HPP), a rare bone disorder characterized by the abnormal development of bones and teeth. This long-term registry will collect and store patient medical information, and other related information to use in medical research...

ALS STUDY TO COLLECT BIOSPECIMENS FOR RESEARCH

Official Title: Answer ALS: The Individualized ALS Treatment Initiative (IATI)

The purpose of this research is to create a large repository of cells, bio-fluid samples (blood and spinal fluid (optional)), and cell lines for ALS gene identification. Samples and information will be used mainly to study ALS and other motor neuron diseases. This will be combined carefully with col...

A Study for Young Toddlers With AND Without Cerebral Palsy (CP)--The APPLES Study

Official Title: Early Childhood Constraint Therapy for Sensory/Motor Impairment in Cerebral Palsy

This study is being done to find out what parents, doctors and therapists can do to help young children that have cerebral palsy (CP) on one side of their body to have better motor abilities. Infants and young children in this study will use a non-invasive soft mitt for Constraint Induced Movement T...

Infantile or Juvenile-Onset Hypophosphatashia (HPP) Study: Examining Asfotase Alfa

Official Title: An Open-Label, Multicenter, Expanded Access Program for Asfotase Alfa (Human Reombinant Tissue-Nonspecific Alkaline Phosphatase Fusion Protein) Treatment for Patients with Infantile or Juvenile-Onset Hypophosphatashia (HPP)

The purpose of this study is to test the safety and tolerability of an invetigational drug, asfotase alfa, for those with Infantile or Juvenile-Onset Hypophosphatashia (HPP). Currently, there are no approved medical treatments for HPP, a rare bone disorder caused by gene mutations or changes (change...

Study of Once Daily Baclofen ER Capsules (GRS) in Spasticity Due to Multiple Sclerosis (MS).

Official Title: A Clinical Evaluation Of The Safety Of Baclofen ER Capsules (GRS) When Administered Once Daily To Subjects With Spasticity Due To Multiple Sclerosis (MS): An Open Label, Long Term, Safety Trial

The purpose of this study is to investigate the long term safety of Baclofen ER Capsules (GRS) when administered once daily to those with spasticity due to Multiple Sclerosis (MS).

Safety Study in Those With Multiple Sclerosis Treated Fingolimod or Other Approved Therapies

Official Title: Long-term, prospective, multinational, parallel-cohort study monitoring safety in patients with MS newly started on fingolimod once daily or treated with another approved disease-modifying therapy

The purpose of this study is to further explore the overall safety of fingolimod over the long term, in those with relapsing MS under conditions of routine medical practice.

Study of Baclofen ER Capsules (GRS) in Those With Spasticity Due to Multiple Sclerosis (MS)

Official Title: A Placebo-controlled Randomized Withdrawal Evaluation of the Efficacy and Safety of Baclofen ER Capsules (GRS) in Subjects With Spasticity Due to Multiple Sclerosis

The purpose of this study is to assess whether Baclofen ER capsules demonstrate efficacy and safety in the treatment of spasticity due to Multiple Sclerosis (MS).

Bone Mineral Density in Young Women with Sickle Cell

Official Title:

The purpose of this study is to examine the effects of different birth control methods on bone health in young women with sickle cell disease. We need women who are taking birth control and those who are not.