Search Results

Displaying studies 1 - 25 of 50 in total


Evaluating Women's Experiences of Childbirth in the Midwestern United States

Official Title: Women's Experiences of Childbirth in the Midwestern United States

The purpose of this study is to interview women about their childbirth experiences, including their interactions with providers, and their own actions and feelings during labor and delivery. The study will also look at how women make decisions and form preferences about who will supervise the birth...

A Study to Evaluate Fasting vs. Non-Fasting Measurement of Bile Acids in Pregnant Women (BAP)

Official Title: Fasting vs. Non-Fasting Measurement of Bile Acids in Pregnant Women (BAP)

This study is being done in order to determine if a fasting state affects the measurement of bile acids in pregnancy.

Using Pravastatin to Prevent Preeclampsia in High Risk Women (PRAVASTATIN)

Official Title: A Randomized Controlled Trial of Pravastatin to Prevent Preeclampsia in High Risk Women (PRAVASTATIN)

This study is being done to determine if the use of pravastatin in subsequent pregnancies will reduce the rates of recurrence of preeclampsia for women who have a history of preterm birth due to preeclampsia.

A Study Using Antihypertensive Therapy for Mild Chronic Hypertension during Pregnancy

Official Title: A Pragmatic Multicenter Trial of Antihypertensive Therapy for Mild Chronic Hypertension during Pregnancy (CHAP)

This study will evaluate the benefits and harms of using medicine in the treatment of mild chronic hypertension (CHTN) in pregnancy.

A Study to Evaluate Effective Medical Management of Pregnancies with Type 2 Diabetes

Official Title: Medical Optimization & Management of Pregnancies With Overt Type 2 Diabetes (MOMPOD)

This study is being conducted in order to compare the safety and effectiveness of insulin vs. insulin plus metformin for treatment of Type 2 diabetes mellitus in pregnancy

A Study to Evaluate Vaginal Versus Intramuscular Progesterone for Prevention of Recurrent Spontaneous Preterm Birth

Official Title: Vaginal Versus Intramuscular Progesterone for Prevention of Recurrent Spontaneous Preterm Birth (VIP)

The purpose of this study is to compare the effectiveness of vaginal progesterone vs. intramuscular progesterone for the prevention of recurrent spontaneous preterm birth.

A Study to Evaluate the Dosage and Frequency of Aspirin in Obese Pregnant Women at Risk for Preeclampsia

Official Title: Platelet Inhibition With Variable Dosages and Frequency of Aspirin in Obese Pregnant Women: A Randomized Trial (ASA)

This study is being done to compare dosages and timing of aspirin administration in women who are obese and at risk for preeclampsia.

A Study Utilizing a Physical Activity Intervention for Gestational Diabetes

Official Title: Physical Activity Intervention for Gestational Diabetes-Moms in Motion

To determine if the use of ankle weights months 1-7 postpartum in mothers with gestational diabetes mellitus will aid with weight loss and reduce the likelihood of them developing Type 2 diabetes long term.

A Study to Evaluate Progesterone and Inflammatory Mediators in High-risk Pregnancies

Official Title: Progesterone and Inflammatory Mediators in High-risk Pregnancies (Cortisol)

This observational study is being conducted to measure the levels of cortisol and other hormones in women who are receiving progesterone therapy to prevent a preterm birth.

A Study to Evaluate the Use of Tranexamic Acid in the Prevention of Obstetrical Bleeding Following a Caesarean Section

Official Title: A Randomized Trial of Tranexamic Acid for Prevention of Obstetrical Hemorrhage after C/S (TXA)

Primary aim goal is to assess whether tranexamic acid when given as a preventative measure, lowers the rates of postpartum hemorrhage in women pregnant with a singleton or twins pregnancy undergoing a cesarean delivery.

Examining Tests Used in the Measuring of Protein Levels to Aid in the Detection of Preeclampsia

Official Title: Preeclampsia Risk Assessment: Evaluation of Cut-offs to Improve Stratification (PRAECIS)

This research study is designed to examine the ability of tests to detect preeclampsia by measuring protein levels in blood, urine, and saliva.

A Study Evaluating the Use of Nitrous Oxide Donor for Labor Induction in Women with PreEclampsia or Gestational Hypertension

Official Title: Use of Nitrous Oxide Donor for Labor Induction in Women with PreEclampsia or Gestational Hypertension (NOPE)

To evaluate the effectiveness of the isosorbide mononitrate (IMN) as a medication to help start labor in women with gestational hypertension and/or preeclampsia.

Postpartum Cardiovascular Dysfunction in Patients with Preeclampsia

Official Title: Persistent postpartum cardiovascular dysfunction in patients with preeclampsia with severe features (ECHO)

To investigate if patients who have preeclampsia are at an increased risk of having heart problems that can be identified on an echocardiogram (an ultrasound of the heart) as well as evaluating whether levels of certain substances in the blood are associated with more abnormalities on the echocardio...

Antithrombin III (AT) Activity in Women with Severe Preeclampsia (PE) or Superimposed PE prior to 31weeks (AT3)

Official Title:

The purpose of this study is to see how the levels of Antithrombin (AT) change in women with preeclampsia. AT is an anticoagulant found in human blood. Preeclampsia is a condition that can develop around the 20th week of pregnancy, characterized by high blood pressure, protein in your urine, and wat...

A Study to Collect a Protein Sample Found in Pregnant Women Showing Signs and Symptoms of Preterm Labor

Official Title: Prospective Sample Collection of Qualitative Fetal Fibronectin In Pregnant Women with Signs and Symptoms of Early Preterm Labor (Hologic #2)

The goal of the study is to collect fFN (fetal fibronectin) samples to further support clinical use of the test from a vaginal fluid specimen taken during pregnancy (from 24 weeks to 35 weeks) to assess the risk of pre-term birth.

A Study to Evaluate Continuous Positive Airway Pressure (CPAP) for Sleep Apnea in Pregnancy

Official Title: A Randomized Trial of Continuous Positive Airway Pressure (CPAP) for Sleep Apnea in Pregnancy (SLEEP)

The purpose of this study is to understand how Continuous Positive Airway Pressure (CPAP) for mild to moderate sleep apnea may affect hypertensive disorders of pregnancy and other complications of pregnancy such as gestational diabetes.

A Study for Pregnant Women with Type 1 Diabetes

Official Title: Hybrid Closed-Loop Therapy in Pregnancies Complicated by Type 1 Diabetes (T1D)

This study is for pregnant women with Type 1 diabetes. The primary aim is to learn more about a specific insulin pump when set in auto mode vs. manual mode and how both modes impact glucose control and fear of low blood sugar.

A Study Looking at the Motivation of Caregivers to Seek and Share Information

Official Title: Surrogate Information Acquisition: Decisions to Seek and Share

Do you provide care to a family member who was recently diagnosed with breast cancer? If so, a research team at Ohio State University wants to hear about your experiences seeking health information. This study consists of an online survey asking questions about your caregiving experience, your in...

A Study to Evaluate the Effects of Acetaminophen on Pain

Official Title: Pain and Acetaminophen in Women Study (PAWS)

Researchers at The Ohio State University are seeking volunteers for a study that is designed to evaluate the effects of acetaminophen on pain response.

Understanding Caregivers' Decisions to Seek and Share Health Information with Care Recipients

Official Title:

This study is interested in understanding what motivates caregivers to seek information on behalf of their care recipients, and how caregivers decide to share that information with their care recipients.

How Changes in Body Mass Following Weight Loss Effect Endometrial Tissue and Blood

Official Title: Effect of adiposity changes on endometrial tissue and blood biomarkers

The goal of this study is to examine how changes in body fat following weight loss impact inflammation in endometrial tissue and blood and whether these processes differ between Black and White women. We are interested in recruiting: 1.) women who are considering or scheduled to undergo bariatric su...

How Chemotherapy Can Affect Gut Health and Cognition

Official Title: Intelligut

This study tests how chemotherapy may affect the diversity of the gut’s microbiome (the bacteria in your gut) and how chemotherapy-induced changes on the gut may affect cognition (how we acquire and understand knowledge).

Postpartum Family Planning

Official Title: Initiation of injectable contraception immediately postpartum among breastfeeding women

To study the effect of postpartum Depo-Provera (DMPA) on milk let-down and on patterns of contraception use.

A Study on Maternal Immune Responsiveness

Official Title: The MIRACL Study: Maternal Immune Responsiveness as Clinical Target for Preterm Birth Prevention

This study will test new methods of identifying women at risk for preterm birth and predicting response to preventive interventions. We will also examine if and how maternal factors affect immune cells of the mother and baby and determine whether this is important to birth outcomes and outcomes for ...

A Study of Mobile Health (mHealth), Breast Disease, and Lifestyle Modification

Official Title: Mobile Health (mHealth), Breast Disease, and Lifestyle Modification: Developing a Grounded Theory

The purpose of this study is to understand breast cancer survivors use of mobile health (mHealth) apps for lifestyle behavior change - eating a healthier diet, exercising more, dealing with stress, & stopping smoking. Interviews will last approximately 60 - 90 minutes.