Search Results

Displaying studies 1 - 25 of 57 in total


A study for children with nearsightedness

Official Title: The Chaperone Study: A multi-center, double-masked, randomized, placebo-controlled, phase III study of the safety and efficacy of atropine 0.1% and 0.01% ophthalmic solutions administered with a microdose dispenser for the reduction of pediatric myopia progression

Is your child nearsighted? Nearsightedness, or myopia, is a condition that results in blurry vision when looking at distant objects. Myopia happens when the eyeball grows too long or the cornea (the clear front cover of the eye) is too curved. As a result, light entering the eye is not focuse...

A Study Designed to Measure Sleep Problems in Children with Autism Spectrum Disorder

Official Title: Measuring Sleep Problems in Children with Autism Spectrum Disorder

To get a better understanding of sleep problems in children with Autism Spectrum Disorder (ASD). Through the use of focus groups with parents of children with ASD, we will use what we learn in this study to improve measurement of sleep problems in children with ASD.

Understanding How Booster Seat and Seat Belt Positioning Affects Safety in Motor Vehicle Crashes

Official Title: Belt Fit and Belt Torso Contact of Children on Belt-Positioning Booster Seats

Researchers at the OSU Injury Biomechanics Research Center are seeking child volunteers to sit on a variety of belt-positioning booster seats in a mock-up vehicle seat. Various measurements will be made of position of seat belts, booster seats, and child’s shoulders and pelvis. We aim to understand ...

A Study to Evaluate the Use of Esketamine in Treating Children and Adolescents at Imminent Risk of Suicide

Official Title: A Double-Blind, Randomized, Psychoactive Placebo-Controlled, Study to Evaluate the Efficacy and Safety of 3 Fixed Doses (28 mg, 56 mg and 84 mg) of Intranasal Esketamine in Addition to Comprehensive Standard of Care for the Rapid Reduction of the Symptoms of Major Depressive Disorder, Including Suicidal Ideation, in Pediatric Subjects Assessed to be at Imminent Risk for Suicide

The purpose of this study is to see if esketamine is effective for treating children and adolescents 12 to 17 years of age with Major Depressive Disorder who are at imminent risk for suicide.

A Medication study for Children with Major Depressive Disorder (Ages 7 -17)

Official Title: A Double-blind, Placebo- and Active-controlled Evaluation of the Safety and Efficacy of Levomilnacipran ER in Pediatric Patients 7-17 Years With Major Depressive Disorder

The purpose of this research study is to evaluate the drug Levomilnacipran extended-release to see how well the drug works, observe the side effects, and how well tolerated it is compared to placebo in pediatric patients with major depressive disorder.

A Study to Evaluate Relationship Dynamics in Families of Children with ADHD and Their Opposite-Sex Siblings

Official Title: Relationship Dynamics in Families of Children with ADHD and Their Opposite-Sex Siblings

This study is being done to better understand relationship dynamics between children with ADHD, their siblings, and their parents. Our goal is to better understand how differences in family dynamics affect children with ADHD. Participants will be asked to fill out several self-report questionnaires ...

Children with Autism Who Use Augmentative and Alternative Communication

Official Title: Lexical Categories in Children with Autism Who Use Augmentative and Alternative Communication

The purpose of this study is to examine the lexical qualities (i.e., the nouns and verbs used) in children with autism spectrum disorder (ASD) who use Augmentative and Alternative Communication (AAC) devices. More specifically, how the different activities your child engages in influences the types ...

A Study on Maternal Immune Responsiveness

Official Title: The MIRACL Study: Maternal Immune Responsiveness as Clinical Target for Preterm Birth Prevention

This study will test new methods of identifying women at risk for preterm birth and predicting response to preventive interventions. We will also examine if and how maternal factors affect immune cells of the mother and baby and determine whether this is important to birth outcomes and outcomes for ...

A Treatment Study for Amblyopia (lazy eye) Vision Improvement

Official Title: Luminopia One Amblyopia Vision Improvement Study

The objective of this research study is to learn more about Luminopia One and determine whether it is a safe and effective treatment for amblyopia. Children are randomly assigned to Luminopia therapy or glasses only for 12 weeks, with monthly visits to OSU. Kids in the Luminopia treatment group wat...

Immune Response in Adolescents

Official Title:

Our goal in this study is to learn more about the immune system in adolescence and early adulthood. We are looking to enroll healthy children ages 12-18 years old. Enrollment in the study will require 1 visit to Nationwide Children’s Hospital involving a blood draw and 2 nasal swabs. The visi...

Children's Autobiographical Memory Study

Official Title: Children's Autobiographical Memory Study

This study examines the developmental changes of how young children remember and talk about memories of their past, how these changes are associated with some parental factors and child characteristics, and how these changes contribute to children’s development in various domains.

Family Learning from Science Media

Official Title: Family Learning from Science Media

STUDY FOR PARENTS OF PRESCHOOLERS. The Children and Media Lab in the School of Communication is looking for parents of preschoolers (ages 4-5) to bring their child to Derby Hall to participate in a 40-minute study. Parents will watch a TV show and engage in science activities with their child. ...

A Study for 11- 21 year olds with Pilonidal Disease

Official Title: A randomized controlled trial of laser depilation in the treatment of pilonidal disease.

A number of studies have found that laser hair removal greatly reduces the recurrence rate of pilonidal disease. Drs. Minneci and Deans, pediatric surgeons at Nationwide Children’s Hospital, are currently conducting a study that will help better understand how laser hair removal can help patients, 1...

A Vitamin and Mineral Supplement for ADHD

Official Title: Micronutrients for ADHD in Youth: The "MADDY" Study

Do you have a child with ADHD? Are you interested in hearing about a vitamin and mineral supplement that may help with irritability? The Ohio State Nisonger Center is currently enrolling for a research study to evaluate an investigational vitamin and mineral supplement for ADHD. The study sup...

Pediatric Eye Study using High Resolution Retinal Imaging

Official Title: High Resolution Retinal Imaging Study in Pediatric Myopic Population

For this study, we would image the cells in the back of your child’s eye to learn more about how cell arrangement within the eye changes during eye growth and development of myopia (nearsightedness).

Nearsightedness in Children--A Study to Determine if Daily Eye Drops Can Slow the Progression

Official Title: CHILDHOOD ATROPINE FOR MYOPIA PROGRESSION (CHAMP): A 3-ARM RANDOMIZED, DOUBLE-MASKED, PLACEBO-CONTROLLED, PHASE 3 STUDY OF ATROPINE SULFATE OPHTHALMIC SOLUTION 0.01% AND 0.02%

The purpose of the study is to determine if a daily eye drop will help slow the progression of nearsightedness in children.

A Study about Tools to Assess Mental Health for Youth with Intellectual Disabilities and Their Caregivers

Official Title: Development and Validation of a Diagnostic Interview to Assess Psychopathology in Youths with Intellectual Disabilities

This study will help researchers to learn more about mental health for youth with intellectual disabilities. The purpose of our study is to develop a diagnostic interview to assess mental health issues in youths with Intellectual Disabilities. The instrument would address a significant need and all...

iPad Game Therapy Study for Lazy Eye (Amblyopia) in children ages 4 to 12

Official Title: Binocular Dig Rush Game Treatment for Amblyopia (ATS20)

This study is designed to determine how well a new iPad therapy game works compared to just wearing glasses in treatment for Lazy Eye (Amblyopia).

Understanding How Children Ages 2 to 5.5 Learn Words------For Children With AND Without Autism Spectrum Disorders

Official Title: LANGUAGE DEVELOPMENT AND THE PROCESSES UNDERLYING LANGUAGE DEVELOPMENT IN CHILDREN WITH AUTISM SPECTRUM DISORDERS

This study investigates word learning in children between 2 and 5.5 years of age. We are comparing word-learning strategies of children with and without autism. The goal of the study is to help us better understand the way children with autism learn, so we can best help them.

A Study for Healthy Adolescents 12-18: Understanding Risk of Cardiovascular Disease and Diabetes

Official Title: Complement and Cardiovascular Risk in Adolescents

This is a study to find out how a part of the immune system called "Complement" affects risk of future diabetes, high blood pressure, heart disease or stroke. Evidence suggests that these diseases which are major causes of death in adults begin in adolescence. There are specific tests that may ide...

The Effects of Media on Children--Ages 8-12

Official Title: Video Game Violence and Gun Violence

The purpose of this study is to examine the effects of media (TV programs, movies, video games) on children. Children will play a video game for 20 minutes, play with some toys and games, and complete a survey about movies, television, video games, how they behave, and guns. Total time of partic...

Physical Therapy Study for Young Children (2 to 8) with Cerebral Palsy

Official Title: A Comparison: High Intense Periodic vs Every Week Therapy in Children with Cerebral Palsy (ACHIEVE)

This study compares intensive vs weekly scheduling models of physical therapy sessions, in order to determine the most effective frequency model of physical therapy for young children with Cerebral Palsy. Participants will receive 40 hours of physical therapy. Participants will be randomly ass...

Babies Helping Babies--A Study for Healthy Babies Under the Age of 2

Official Title: Host Immune Responses to Microbial Pathogens

This study is seeking babies who do NOT have infections. The purpose of this research study is to look at how the body responds to infection (immune response) caused by different types of microbes (bacteria and virus). To understand how the immune response to infection works, blood samples from peop...

The BabyTalk Study--For Children With and Without Hearing Loss

Official Title: Infant-Directed Speech and Language Development in Infants with Hearing Loss

The BabyTalk Project examines how children with and without hearing loss develop language over time. Specifically, we are interested in how young children learn new words and how different speaking styles (e.g., "motherese") may influence the process of linking a new word to an unfamiliar object.

Parent-Infant Eye Tracking Study for Children With and Without Hearing Loss

Official Title: Development of Parent-Child Interactions

This study will examine how a child’s hearing loss may affect the dynamics of parent-child interactions. The study will observe how normal-hearing and hearing-impaired child learn novel words during videotaped parent-child interactions. Individual study visits may last 30-45 minutes, and there ...