Research studies are looking for volunteers just like you. Both healthy volunteers and participants with specific health conditions are needed to help answer important questions impacting the health of our friends and family. Join us to improve the health of others.

Study Categories

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  • Interview Study for Caregivers of Older Adults with Memory Problems

    Official Title

    CareNet: An Interactive Digital Tool to Assess Informal Caregiving Networks of Older Adults with Dementia

    Purpose

    We are interested in understanding the dynamics of caregiving when multiple caregivers are involved in caring for an older adult with memory problems. We would like to interview the primary caregiver in a brief one-time interview about their thoughts and experiences in providing care for an older adult with memory problems. 

    Could this study be right for you?

    Participants must be:

    • An unpaid caregiver of an older adult with memory loss problems
      • The older adult must be 65 years or older
      • The older adult must not live in a residential care/assisted living facility
    • Able to identify at least one other unpaid caregiver for the older adult with memory loss problems
    • Able to communicate in English

    Age Range

    18 years and up
  • Spinal Cord Stimulation and Small Fiber Peripheral Neuropathy

    Official Title

    Spinal Cord Stimulation and Small Fiber Peripheral Neuropathy

    Purpose

    The purpose of this study is to determine whether spinal cord stimulation (SCS) will reduce pain in patients with painful Diabetic Peripheral Neuropathy (DPN).

    Could this study be right for you?

     

    Inclusion Criteria:

    • Over 18 years old
    • Diagnosis of diabetic peripheral neuropathy refractory to treatment with gabapentin or pregabalin and at least 1 other class of analgesic
    • Diagnosis of medically refractory pain secondary to diabetic neuropathy
    • Presence of pain for 12 months

    Exclusion Criteria:

    • Severe medical comorbidities that, in the opinion of the surgeon, exclude the patient from surgical intervention
    • Spinal disease with severe spinal stenosis or spinal cord compression in the region of the proposed spinal cord stimulator lead placement
    • Coagulopathy that cannot be corrected
    • Unable to discontinue blood thinning medications

    Inclusion and Exclusion Criteria varies, please contact Study Coordinator. 

    Age Range

    18 years and up
  • Diabetic Foot Ulcer Study

    Official Title

    Concurrent optical and magnetic stimulation (COMS) for treatment of refractory diabetic foot ulcer; a prospective randomized, sham-controlled, double-blinded, pivotal clinical trial

    Purpose

    The purpose of this study is to evaluate the safety and effectiveness of the treatment with the COMS One device in subjects with refractory diabetic foot ulcers (DFUs). 

    The duration of this study will last up to 28 weeks. 

    Could this study be right for you?

    Inclusion

    • Male and females aged 22 to 90 years old 
    • Able to understand and sign the informed consent form (ICF) and comply with requirements set in the protocol including trial visits, trial treatment and dressing regimens and compliance with required offloading device (if applicable)
    • Type 1 or Type 2 diabetes mellitus

    Exclusion

    • Known pregnancy or lactating
    • Active skin cancer, a history of skin cancer or any other localized cancer, precancerous lesions or large moles in the areas to be treated
       

    Inclusion and Exclusion Criteria varies, please contact Study Coordinator for more information. 

    Age Range

    22 - 90 years
  • Share your Experience: Exploring Gastrointestinal Symptoms and Food Struggles

    Official Title

    In Their Own Words: A Qualitative Exploration of Food Insecurity in the Lives of Patients with Gastrointestinal Disorders

    Purpose

    The purpose of this study is to better understand the daily food- and nutrition-related experiences of people with GI symptoms through a virtual interview. 

    There has been very little research on how food challenges affect those with GI symptoms and conditions.

    We think you may have valuable insights, Your Voice Matters! 

     

     

     

     

     

     

     

    Could this study be right for you?

    • 18 + years old 
    • Have experienced any level of food-related concerns within the past 12+ months 
    • Living with GI symptoms and/or diagnosed GI condition 

    Age Range

    18 years and up
  • A Study for those with Treatment Resistant Epilepsy & Anxiety

    Official Title

    An open-label clinical trial evaluating the ExAblate Model 4000 Type-1 focused ultrasound unilateral thalamotomy for patients with treatment-refractory focal onset epilepsy and comorbid anxiety

    Purpose

    The purpose of the study is to learn more about whether an ultrasound treatment for epilepsy and anxiety is safe and effective.

    Could this study be right for you?

    • Age: 18-65 years old
    • Treatment resistant Epilepsy (focal or partial-onset seizures)
    • ≥ 3 seizures/month
    • Moderate-to-severe Anxiety

     

     

    Age Range

    18 - 65 years
  • A Study Evaluating How Dietary Fat Affects Cognition

    Official Title

    Essential Fats For Enhancing Cognitive Thinking (EFFECT) Study: Dietary Fat Quality and Cognitive Impairment

    Purpose

    The purpose of the EFFECT Study is to determine how dietary fats influence cognitive (mental) function in adults.

     

    During the 7-week study participants will

    • Consume one study food per day for a total of 3 weeks
    • Have their blood drawn
    • Have their body weight and shape measured
    • Complete cognitive tests
    • Fill out questionnaires
    • Complete diet and physical activity recalls

    Could this study be right for you?

    • Feel your memory or concentration is not as good as you'd like it to be
    • Are overweight
    • Do NOT have diabetes
    • Do NOT have dementia or Alzheimer's
    • Do NOT have food allergies 
    • Are NOT pregnant or nursing an infant

    Age Range

    40 - 75 years
  • Variations in Ketone Metabolism

    Official Title

    Strategies to Augment Ketosis- Variations in Ketone Metabolism

    Purpose

    This study is being done to see how individuals respond to a ketone ester (KE) across different age groups and health statuses. With the ketogenic diet becoming more popular, research on ketones (a molecule created when fat is broken down in the body) has grown as well. 

    These findings will be used to help develop future research studies and help others to pick the right doses of ketone supplement.

    Could this study be right for you?

    • Do NOT smoke or have diabetes, liver disease, kidney disease, cardiovascular disease, or any form of endocrine dysfunction 

    • Have NOT experienced >10% weight loss in the last 6 months 

    • Do NOT currently consume a low carbohydrate diet 

    • Do NOT consume alcohol more than 3 drinks/daily or 14 drinks/weekly 

    • Do NOT suffer from food allergies or gastrointestinal disorders 

    Age Range

    20 - 70 years
  • Sleep Restriction and Ketone Supplements

    Official Title

    Strategies to Augment Ketosis: Ketone Conferred Resiliency Against Sleep Restriction (STAK-Sleep)

    Purpose

    To examine if drinking a ketone supplement, twice a day, can improve brain, digital shooting, and physical performance during short-term sleep restriction (4 nights, 50% of normal sleep).

    Could this study be right for you?

    • Healthy
    • Age: 18 - 40 years old
    • BMI: 20-35 kg/m2
    • No diagnosed sleep disorders
    • Not consuming a ketogenic diet

    Age Range

    18 - 40 years
  • Emerging Adulthood and Parenthood Study

    Official Title

    Emerging Adulthood and Parenthood Study

    Purpose

    The Emerging Adulthood and Parenthood Study is a qualitative study designed to identify relevant factors and themes related the transitions to adulthood and parenthood in a sample of fathers. We will use qualitative, semi-structured interviews with parents to extract these themes and discuss important aspects about transitioning through life stages. After conducting these interviews, the identified themes will be utilized in the creation of questionnaire to measure the transition to parenthood. The goal of the study is to create a self-report questionnaire measure that captures the domains of emerging adulthood and emerging parenthood.

    We are currently looking to recruit fathers for our study. 

    Could this study be right for you?

    • Must have at least one biological child
    • Is/was one of the primary non-gestational caregivers (fathers) of that child
    • Speaks English as a first language

    Age Range

    18 - 65 years
  • Exogenous Ketone Study

    Official Title

    Strategies to Augment Ketosis: Optimization of Ketone Delivery Strategies (STAK: OK'd)

    Purpose

    This study is intended to evaluate the effects of different dosing measurements for different ketone products in healthy male adults. After giving consent to this study you will schedule 9 testing sessions about 3 days apart. During these sessions you will come into the Physical Activity and Education Services (PAES) building in the morning, having had no food that day and take a study product. Various tests will be administered after ingestion. You will have blood draws to tell us more about your metabolic response to the product.

    Could this study be right for you?

    • Have a BMI >18 kg/m2 or ≤29 kg/m2
    • Do NOT smoke or have diabetes, liver disease, kidney disease, cardiovascular disease, or any form of endocrine dysfunction
    • Do NOT currently consume a low carbohydrate diet

     

    Age Range

    20 - 30 years
  • A Study Investigating a Medicine to Improve Social Communication in Adolescents and Adults with Autism Spectrum Disorder (ASD).

    Official Title

    MapLight Study (IRIS Clinical Trial)

    Purpose

    The purpose of this study is to investigate a medication intended to improve social communication in adolescents and adults with ASD.

    Could this study be right for you?

    • Have an autism diagnosis or suspect you have an autism diagnosis
    • Have a caregiver or study partner willing to enroll in the study with you

    Age Range

    18 - 45 years
  • A Feasibility Study to Assess the Effect of a Ketogenic Diet as a Co-Therapy for Major Depressive Disorder

    Official Title

    Ketogenic Intervention in Depression (KIND)

    Purpose

    The overarching goal of this pilot study is to: (1) demonstrate that a well-formulated KD can be implemented in treatment program for major depression, and (2) test whether such a program results in reductions of symptoms of depression. 

    Could this study be right for you?

    Inclusion Criteria:

    • OSU students (age 18-30 years at the time of enrollment) with confirmed major depressive disorder as determined by SCID-5 diagnosis at baseline testing.
    • Currently engaged in counseling and or mediation treatment for depression
    • Available for a 12-week period and indicate willingness and ability to eat KD foods as prescribed

    Exclusion Criteria:

    • Disordered eating, as evidenced by meeting criteria for Anorexia Nervosa, Bulimia Nervosa, Binge Eating Disorder, Other Specified Eating Disorder, Unspecified Eating Disorder, or Avoidant Restrictive Eating Disorder during the SCID-5 interview at baseline testing.
    • Substantial imminent risk of suicide as assessed during the SCID-5 interview.
    • Body mass index (BMI) < 20 kg/m2
    • Habitual consumption of a structured low-carbohydrate diet in the last 6-months

    Exclusion Criteria varies, please contact Study Coordinator.

     

    Age Range

    18 - 30 years