Participants must meet the following criteria:
- Native English speaker
- Able to have an MRI
- Had only one stroke (in the left hemisphere of the brain)

If you’ve had or will have surgery to treat a cancer diagnosis, you can help researchers at Ohio State examine how patient spirituality and/or religion influences the cancer journey by taking an online survey.

Participants should be:

• Over 18 years old.

• Diagnosed with cancer (all types).

• At least four months past the initial cancer diagnosis.

• Underwent or will receive a surgical procedure related to their cancer

• Able read and write in the English language.

Inclusion Criteria (not a complete list): - Males or females of at least 18 years of age - You must have received benzodiazepines before or after arrival to the Emergency Department for generalized convulsive seizures lasting > 5 minutes Exclusion Criteria (not a complete list): - Intubated or "to be" intubated - A known allergy or sensitivity to progesterone or allopregnanolone medications/supplements - Status Epilepticus is due to acute anoxic brain injury, cardiac arrest, acute trauma, hyper-/hypo- glycemia - Known or suspected pregnancy

1. Male or female, age 30 or older
2. Has not received deep brain stimulation, Carbidopa (CD)/Levodopa (LD) enteral suspension, or any other Parkinson's Disease (PD) medication as continuous daily infusion
3. Subject does not have a history of significant skin conditions or disorders
4. Subject does not have a recent (within 6 months before screening) history of drug or alcohol abuse
5) Subject does not have a history or presence of psychotic episodes
6) Subject does not have other clinically significant unstable medical conditions
7) Subject must have a diagnosis of levodopa-responsive idiopathic PD

* other eligibility criteria to be discussed/reviewed with the study team

- Patient must be age 18 years of age or older. - Patient must have a confirmed cancer diagnosis for which VEGFRi treatment is indicated, and must be currently under VEGFRi-based anti-cancer therapy with stable dosage for ≥ 1 week. - Patient on pain medications is allowed provided they have been on stable dosage in the past 1 week and is going to continue at the same dosage.

Inclusion:
- Man or woman, at least 30 to 80 years old
- Have early-stage Parkinson's disease
- Not be on any current treatments for PD
- If of reproductive potential, willing and able to use a highly effective form of birth control during the study and for 30 days following last dose of study material

* Other criteria for eligibility apply

Exclusion:
- Diagnosis of secondary or atypical parkinsonism
- Onset of any parkinsonian motor sign or symptom >5 years before Screening Visit
- Previous surgical procedure for PD
- Clinically significant medical, surgical, psychiatric, or laboratory abnormality
- Has an ECG or clinical evidence of potentially unstable heart disease
- Medical or recreational use of marijuana or THC-containing compounds within 3 months of the Screening Visit

* Other criteria for exclusion apply

You may be eligible if you:
• Are Between the ages of 40 to 80 years
• Are willing to practice effective birth control, or remain abstinent during the trial and for 4 weeks after the last dose of trial if you are a sexually active man or woman of childbearing potential
• Were diagnosed more than 3 years ago
• Willing and able to not use any PD medications that are not permitted by the protocol (including dopaminergic agents) throughout participation in the trial.

You will be excluded if you:
• Have a history or clinical features consistent with essential tremor, atypical or secondary parkinsonian syndrome (including, but not limited to, progressive supranuclear palsy, multiple system atrophy, cortico-basal degeneration, or drug-induced or post-stroke parkinsonism).
• Have had previous surgical intervention (eg, deep brain stimulation) for PD or for whom such a procedure is planned or anticipated during the trial period.
• Have hypertension.
• Have previously participated in any tavapadon trial, including this trial, and received IMP.
• Have received treatment with any other investigational drug within 60 days before signing the ICF.

- Are at least 18 years and ≤60 years for males (≤70 years of age for females) at
the time of informed consent

- Are able to read, understand, and give documented (electronic or paper
signature) informed consent

- Current AA episode of more than 6 months’ duration and hair loss
encompassing ≥50% of the scalp

- No spontaneous improvement over the past 6 months

Inclusion criteria: - Between the ages of 18 and 65 - Currently depressed - Currently taking an antidepressant - Have tried at least 2 antidepressant medications

1. No prior delivery at or after 20 weeks 0 days of gestation
2. Pregnancy with only one fetus
3. Gestational age at randomization between 14 weeks 0 days and 21 weeks 6 days
4. Diagnosis with mild to moderate OSA as defined by an AHI score ≥ 5 and <30

- Healthy adults who run 5 to 20 miles per week
- Have NOT been injured while running in the past six months
- Have NOT been medically diagnosed with breathing deficiencies
- must be age 18 or older
Those who are interested in participating will be directed to complete a survey, found at go.osu.edu/RunningAndBreathing, to ensure that they meet the previously mentioned criteria.

• Be between 18 - 75 years of age
• Previously prescribed ART for at least 6 months
• Screening HIV RNA is greater than 200 copies
• Women must not be pregnant, planning to become pregnant, or breastfeeding. Women who can become pregnant must agree to use 1 form of effective birth control
• Evidence of non-adherence to previous HIV medications