A Study to Prevent Maternal Peripartum Infection

Official Title: A randomized controlled trial of treatment of bacterial vaginosis in late third trimester to prevent maternal peripartum infection (BV)

Purpose:

The purpose of the study is to find out if antibiotic treatment for bacterial vaginosis can reduce infections in mothers and their babies. Bacterial vaginosis is an imbalance between the good and the bad bacteria normally present in the vagina. If you agree to participate in the study and signed the consent form, you will be screened for bacterial vaginosis. The screening will take around 5 minutes. If you test positive for bacterial vaginosis, you will be asked to continue in the study. You will be randomly assigned to one of two groups: the antibiotic group or the control group.

Eligibility criteria:

You may be eligible or this study if you are:
• A pregnant woman between the ages of 18 and 50 years with the ability to give informed consent.
• Expecting to have a vaginal delivery
• Gestational age of at least 35 weeks

You may be ineligible if you:
• Are planning for elective cesarean delivery
• Have Allergy or contraindications to metronidazole
• Receive of metronidazole or clindamycin on admission for delivery for other indications.
• Have Hemodialysis
• Have severe liver dysfunction
• Report BV to nurse or clinician provider at current clinic visit or has been treated for BV within the past 3 months.

Contact Information


Anna Bartholomew, MPH, BSN, RN, CCRP
614-685-3229
Anna.Bartholomew@osumc.edu

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