COVID-19 Determinants of Disease Severity, Perinatal Transmission, and Immune Response to COVID-19 Vaccine

Purpose:

To identify the factors that determine disease severity, immune development, and perinatal transmission in COVID-19 infections.

Eligibility criteria:

Inclusion criteria

Cohorts 1: Suspected/Infected Individuals (inpatient or outpatient)
1) All ages
2) Suspected or confirmed COVID-19 infection
3) Parents, guardians or patients over the age of 18 years of age must sign the informed consent; and children older than 9 years of age should sign assent, as required.

Cohort 2: Pregnant Women and/or their Infants*
1) Suspected or confirmed COVID-19 infection AND
2) Pregnant women in any stage of gestation, or within 14 days of a 20+ week gestation delivery; we may enroll mothers alone in situations where they choose for their newborn to not participate OR
3) Infants born to eligible mothers; in situations where the mother does not participate in the study, we may enroll infants born to infected women individually into this cohort

*Pregnant women without suspected or confirmed COVID-19 infection will also be enrolled as a healthy control group and will follow the same visit schedule.

Cohort 3 Vaccinated Children, Adults, Pregnant/Lactating Women and/or their Infants
• Pregnant/lactating women with intent to receive a COVID-19 vaccine; we may enroll mothers alone in situation where they choose for their newborn to not participate OR
• Infants born to eligible mothers; in situations where the mother chooses not to participate in the study, we may enroll their infant separately. OR
• Children/Adults of any age with intent to receive a COVID-19 vaccine

Cohort 4 Healthy Controls
• Anyone without an acute illness at the time of enrollment who agrees to participate in the study.

Exclusion criteria
a) Individuals who refuse participation in the study.

Contact Information


Anna Bartholomew, MPH, BSN, RN, CCRP
614-293-3229
Anna.Bartholomew@osumc.edu

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