Mapping Individual Differences in Mood and Personality - The MindMap Study

Mental Health
Official Title Mechanisms of Negative Affectivity

Purpose

Symptoms related to depression and anxiety can affect a person’s daily life and relationships. Some research suggests that people with mood and anxiety disorders process information differently than people without these types of disorders.

The purpose of this study is to better understand the way the brain works in people who have depression and anxiety. Researchers hope their findings will lead to better ways to diagnose and treat mood and anxiety disorders in the future.

Participation involves an initial phone call and a 3 to 5 hour visit to find out if you are eligible. This visit will include completing questionnaires and interviews. If eligible, participants will have a second 3-5 hour visit for an MRI scan.

The 3rd and 4th visits (at 6 and 12 months) will include 1.5 to 3 hours of questionnaires and interviews each.

Following the scan, the 6-month follow-up, and the 12-month follow-up, participants will also complete daily online questionnaires for 7 days.

Could this study be right for you?

You may be eligible for this study if you are:

  • 18-25 years of age
  • Right-handed
  • Currently experiencing symptoms of depression or anxiety (feeling down or depressed, anxious, nervous, or tense, having no interest in things you used to enjoy, or feeling hopeless)
  • Not currently receiving treatment (psychiatric medications or therapy)
  • No major medical problems (e.g., stroke, heart disease, high blood pressure, endocrine disorders, etc.)
  • No history of neurological disorders (e.g., seizures, head injury, etc.)
  • Normal vision, vision that is corrected to normal with glasses or contacts
  • Willing and able to undergo fMRI scanning (not claustrophobic, no non-removable metal in your body)
  • Not pregnant

Participation involves an initial phone call and a 3 to 5 hour visit to find out if you are eligible. This visit will include completing questionnaires and interviews. If eligible, participants will have a second 3-5 hour visit for an MRI scan.

The 3rd and 4th visits (at 6 and 12 months) will include 1.5 to 3 hours of questionnaires and interviews each.

Following the scan, the 6-month follow-up, and the 12-month follow-up, participants will also complete daily online questionnaires for 7 days.

Age Range

18 and up