Pramipexole versus Escitalopram to Treat Comorbid HAND and MDD in HIV Infection
Official Title
An Open-Label, Randomized Controlled Trial of Pramipexole versus Escitalopram to Treat Major Depressive Disorder (MDD) and Comorbid MDD with Mild Neurocognitive Disorder (MND) in Persons Living with HIV
Purpose
This study will evaluate the safety & efficacy of pramipexole vs. escitalopram for treatment of major depressive disorder (MDD) and comorbid MDD/mild neurocognitive disorder (MND) in people living with HIV.
Could this study be right for you?
- People living with HIV ages 18-70
- Diagnosis of MDD alone or with comorbid MDD/MND
- On ART for at least 3 months with HIV RNA <200 copies within 90 days