Spironolactone Versus Doxycycline for the Treatment Acne in Women

Official Title A Randomized, Double-Blind, Multi-Center Comparative Effectiveness Study Of Spironolactone Versus Doxycycline Hyclate For The Treatment Of Acne In Women

Purpose

To determine whether spironolactone is non-inferior to the oral tetracycline-class antibiotic doxycycline hyclate in the treatment of acne in women 

Could this study be right for you?

  • Assigned female at birth  

  • Acne defined as at least 10 inflammatory papules or pustules 

  • Not currently pregnant or planning to become pregnant  

  • Willing to attest to abstinence or some form of contraception for the duration of the study (4 months). Approved options of birth control to use during the study include:  

    • Hormonal contraception (for example, birth control pills, injection, implant, transdermal patch, vaginal ring)  
    • Intrauterine device (IUD)  
    • Tubal ligation (tying your tubes)  
    • Partner with a vasectomy  
    • Male or female condom with spermicide  
    • Diaphragm with spermicide  
    • Cervical cap contraceptive sponge with spermicide  

Age Range

16 - 40 years