A Study of Psilocybin-Assisted Therapy for Adults with Posttraumatic Stress Disorder (PTSD)
Official Title
A Randomized Mechanistic Study of Effect of Psilocybin Combined with Mindfulness-based Therapy vs Support on Posttraumatic Stress Disorder (PTSD)
Purpose
This study will look at the effects of psilocybin-assisted therapy on brain function and mental health. If eligible, you will be asked to complete brain scans (fMRI, EEG), blood tests, and surveys about your mental health before and after you receive a dose of psilocybin. In addition, you will participate in virtual and in-person therapy sessions.
Could this study be right for you?
General Inclusion Criteria:
- Been diagnosed with Posttraumatic Stress Disorder (PTSD) and experiencing active symptoms
- Experiencing active depression symptoms
General Exclusion Criteria:
- Diagnosis of cardiovascular disease, hypertension, or arrhythmia
- Current or past diagnosis of schizophrenia spectrum or other psychotic disorders
- Clinically significant medical or neurological condition
- History of substance use disorder within the past 12 months