A Study for Those Going Through Cardiac Rehabilitation--Measurement of Mitochondrial Dysfunction in Those with and without Diabetes

Official Title

Measurement of Mitochondrial Dysfunction Using Phosphorus Magnetic Resonance Spectroscopy in Diabetic Patients Undergoing an Exercise Regimen

Purpose

We are looking at parts of the cells in our bodies (called mitochondria). Mitochondria give our cells energy and help them stay healthy. People with diabetes have mitochondria which do not work as well as the mitochondria in people without diabetes.

In this study, we want to see if exercise (cardiac rehabilitation) will cause your mitochondria to work better. Using a magnetic resonance imaging (MRI) machine, we can measure how much your cardiac rehabilitation has helped your mitochondria. We will be looking at your leg muscle and the mitochondria in those cells.

In this study, we hope to show that we can help those with diabetes by making their mitochondria work better using things like exercise. We will be looking for people who are beginning cardiac rehabilitation, some with and some without diabetes.

Could this study be right for you?

- 18 yrs and older
- Have been referred for cardiac rehabilitation
- Are able to have an MRI (study coordinator can screen you for this)

Age Range

18 and up