A Study for Veterans with Post-Traumatic Stress Disorder (PTSD)
Official Title
Examining the safety and clinical efficacy of psilocybin therapy for Veterans with PTSD: An open label proof-of-concept trial
Purpose
The study will demonstrate the safety and efficacy of psilocybin in treating post-traumatic stress disorder (PTSD) in veterans. Psilocybin-assisted therapy has shown great promise in treating anxiety symptoms that comprise post-traumatic stress disorder (PTSD). Current therapeutic treatments for PTSD are difficult to tolerate and limited in efficacy, especially in the US military veteran population. This study will examine the safety and efficacy of two psilocybin sessions, combined with psychotherapy, among military veterans with severe, treatment resistant PTSD.
Could this study be right for you?
Inclusion criteria:
- Be a United States military veteran
- 21 to 64 years old
- Have at least a high-school level of education or equivalent (e.g. GED)
- Current diagnosis of PTSD
- Be medically stable as determined by screening for medical problems via a personal interview, a medical questionnaire, a physical examination, an electrocardiogram (ECG), and routine medical blood and urinalysis laboratory tests
Exclusion criteria:
- Women who are pregnant
- Cardiovascular conditions: coronary artery disease, stroke, angina, uncontrolled hypertension, a clinically significant ECG abnormality (e.g., atrial fibrillation), artificial heart valve, or TIA in the past year
- High blood pressure
- History of seizures or epilepsy
Exclusion Criteria varies, please contact Study Coordinator.