Can Soft Soy Pretzels Help Fight Inflammation and Change Immune Health?
Official Title
Examining the efficacy of a soft soy pretzel intervention in altering chronic inflammation and immune profiles in obese individuals
Purpose
The objective of this study is to evaluate if soy isoflavones, delivered via soft soy pretzels (SSP), can be an effective, feasible intervention for chronic inflammation.
All study visits will be at The Ohio State University Medical Center and the study will last 8 weeks and involve 7 clinic visits.
Could this study be right for you?
You may be eligible if you:
- Are a male between 18 and 49 years old
- Have a body mass index (BMI) less than 25 or greater than or equal to 30
- Are not allergic to soy or soy-containing products
- Are not actively trying to lose weight
Exclusion criteria:
- Current or prior history of Type 2 diabetes mellitus as defined by ICD-10-CM E11
- Current or prior history of cancer (excluding non-melanoma skin cancers)
- History of blood clotting disorders or adverse events relating to blood draws
- Use of antibiotic regime lasting longer than one week within the last six months
- Strict veganism (no consumption of animal, fish, or egg products)
- Heavy alcohol consumption (defined as consumption of >14 drinks/week on average)
- Current or prior history of any condition that causes altered immunity such as chronic inflammatory disease, autoimmune disorders, cancer, anemia, and blood dyscrasias
- Regular usage of inflammation lowering medications which include but not limited to nonsteroidal anti-inflammatory drugs such as aspirin, ibuprofen, and naproxen, or anti-pyretic medications such as acetaminophen