Official Title Extracellular vesicles and the development of COPD

Purpose

The study is being done to learn more about how certain smokers develop COPD, chronic obstructive pulmonary disease. By studying microscopic particles (extracellular vesicles) in the blood and lung fluid from smokers we can learn more about this process. This information could lead to better understanding of how smoking damages the lungs and could ultimately help design treatments for people with or at risk for COPD

Could this study be right for you?

• 21 years of age and older
• Current Smoker with at least 10 pack year history
• With or without diagnosis of COPD
• Willing to participate in bronchoscopy procedure
• Not currently diagnosed interstitial lung disease (i.e. sarcoidosis, idiopathic pulmonary fibrosis), lung cancer, primary pulmonary hypertension or have active cardiac disease

Age Range

21 and up

Official Title Biomarkers of Sickle Cell Lung Disease -BOLD

Purpose

This is a study to determine risk factors for developing lung disease in children with sickle cell disease (SCD). Specifically we are researching factors that lead to the development of Acute Chest Syndrome, a pneumonia-like illness that affects many children with SCD.

Could this study be right for you?

• Diagnosis of Sickle Cell Disease (SCD)
• Under the age of 19