Official Title Randomized Proof-of-Concept Trial to Evaluate the Safety and Explore the Effectiveness of a Plant Polyphenol for COVID-19

Purpose

The purpose of this trial is to determine whether a commercially available dietary supplement may decrease the severity of patients with early COVID-19

Could this study be right for you?

Inclusion Criteria:

• Outpatients who test positive for infection with SARS-CoV-2
• Age 45 years and older
• Experiencing COVID 19 symptoms for 7 days or less, OR 72 hours of new respiratory symptoms
• Patient must have access to the internet or a smartphone to complete surveys
• English-speaking patients

Age Range

45 and up

Official Title Creation of a pediatric healthy control repository for clinical diagnostic immunology test development and validation

Purpose

A test for healthy adults from 19 - 75 years old to develop normal values for interpretation of immunological tests in adults with disorders of the immune system.

Voluntary participation involves blood draw at Nationwide Children's hospital. Qualified participants would be eligible to provide a sample every 2 months (not more than 6 times per year).

Could this study be right for you?

If you are:

• An adult 19 years of age or older
• Healthy with no significant medical diagnoses
• Have no chronic conditions that can affect results of immunological studies
• Not on any medication known to alter immune status or function
• Have not undergone recent surgery, chemotherapy, radiation or transplantation
• Non-smoker
• Body mass index (BMI) in healthy range
• No infections within last 2 months

Age Range

19 and up

Official Title Creation of a pediatric healthy control repository for clinical diagnostic immunology test development and validation

Purpose

This study uses healthy children from newborns to 18 years old to help understand immune disorders. This study will compare healthy children and teens to children and teens with disorders of the immune system.

Volunteers will visit Nationwide Children's Hospital (NCH) for a blood draw either one time or not more than once every three months.

Could this study be right for you?

If your child is:

• Newborn to 18 years of age
• Healthy with no significant medical diagnoses
• Has no chronic medical conditions that can affect results of immunological studies
• Is not on any medication known to alter immune status or function
• Has not undergone recent surgery, chemotherapy, radiation or transplantation
• Has had no infections within the last 2 months

Official Title A PILOT, PHASE 2, RANDOMIZED, PLACEBO-CONTROLLED, DOUBLE-BLIND, STUDY TO EVALUATE EFFICACY, SAFETY, TOLERABILITY, PHARMACOKINETICS, PHARMACODYNAMICS AND PHARMACOGENETICS OF CC-220 IN SUBJECTS WITH SYSTEMIC LUPUS ERYTHEMATOSUS

Purpose

The purpose of this study is to test the effects of a new drug called CC-22. Researchers want to find out if it does or does not improve the symptoms of those diagnosed with Systemic Lupus Erythematosus (SLE).

Could this study be right for you?

You may be eligible for this study if:

• You have been diagnosed with SLE
• You have had SLE longer than (or equal to) six (6) months
• You have three (3) or more tender joints at the baseline visit
• You have skin manifestations of Lupus

Age Range

18 and up