A Study to Better Understand Fainting--The ENCHANT Study--seeking healthy 12-20 year olds

Official Title Electrographic and Neurohormonal Characteristics of Adolescent Nausea during Tilt Table Testing, The ENCHANT Study

Purpose

Researchers are looking for healthy young volunteers in order to understand what happens when someone faints. They want to know about changes in children and teenagers who frequently faint, and compare those who faint to healthy people who do not normally faint.

Researchers want to learn more about what happens to the brain and the stomach when people faint. The electroencephalogram or EEG measures brainwaves. The electrogastrogram or EGG records stomach electrical activity. The goal of this study is to measure how gastric electricity changes during fainting. They will use the EEG to confirm that fainting happened. Researchers will compare results of those who are healthy to patients who faint.

Some individuals with fainting or frequent lightheadedness can have excessive nausea. This is'orthostatic nausea', which means nausea with standing. The purpose of this study is to measure hormones from the blood and electrical changes in the stomach during tilt-table testing in patients and healthy controls. Researchers hope to identify the physiologic changes that lead to orthostatic nausea.

Could this study be right for you?

  • Ages 12-20
  • No prior fainting or frequent dizziness/lightheadedness
  • No prior anxiety or depression
  • No medicines that can affect dizziness/lightheadedness
  • No difficulties with nausea or abdominal pain
  • Normal weight

Age Range

12 and up