A Study for those with Treatment Resistant Epilepsy & Anxiety

Official Title
An open-label clinical trial evaluating the ExAblate Model 4000 Type-1 focused ultrasound unilateral thalamotomy for patients with treatment-refractory focal onset epilepsy and comorbid anxiety
Purpose

The purpose of the study is to learn more about whether an ultrasound treatment for epilepsy and anxiety is safe and effective.

Could this study be right for you?
  • Age: 18-65 years old
  • Treatment resistant Epilepsy (focal or partial-onset seizures)
  • ≥ 3 seizures/month
  • Moderate-to-severe Anxiety

 

 

Age Range
18 - 65 years

A Study Investigating a Medicine to Improve Social Communication in Adolescents and Adults with Autism Spectrum Disorder (ASD).

Official Title
MapLight Study (IRIS Clinical Trial)
Purpose

The purpose of this study is to investigate a medication intended to improve social communication in adolescents and adults with ASD.

Could this study be right for you?
  • Have an autism diagnosis or suspect you have an autism diagnosis
  • Have a caregiver or study partner willing to enroll in the study with you
Age Range
18 - 45 years

Neurodevelopmental Effects of Youth Tackle Football

Official Title
Understanding the Neurodevelopmental Effects of Youth Tackle Football Participation
Purpose

In this study we are aiming to identify risk factors for higher exposure to football-related neurotrauma in youth tackle football players and to determine the effects of football-related neurotrauma exposure on neurodevelopment in children with no previous tackle football participation.

For this specific posting, we are looking for boys ages 8-12 who are non-athletes or athletes who play non-contact sports to serve as control subjects for our fMRI study. 

Could this study be right for you?

We are looking for boys ages 8-12 who are either non-athletes or do not participate in any contact sports

  • Boys must have no metal implanted in the body
  • Have no prior history of head trauma
  • Have no serious health or mental health diagnoses
  • Must not have a fear of enclosed spaces
Age Range
8 - 12 years

Exploring the Development of the Infant and Fetal Brain

Official Title
Exploring the Connectivity and Functional Organization of the Infant Brain
Purpose

The purpose of the study is to investigate how the brain that we are each born with leads to our own unique behavior later in life, and the similarities and differences between maternal and child brains. We are studying infants prenatally and postnatally, following up with them as they grow and develop, and studying their mothers to understand how similar/different they are to their child.

Could this study be right for you?
  • Infants under 3 years of age, and pregnant persons who are at least 20 weeks pregnant
  • All participants must have no metal implanted in the body
  • Have no significant health conditions or history of serious mental illness
  • Not suffer froma (fear of enclosed spaces)
  • Pregnancies must be without complication.
Age Range
Up to 40 years

Research Study on Light Sensitivity after Head Injury

Official Title
Effect of Fixation Training with Colored Light Targets on Traumatic Brain Injury-Associated Photophobia
Purpose

Researchers at The Ohio State University College of Optometry are seeking individuals with a recent history of head trauma who are experiencing light sensitivity. The goal of this study is to determine if daily 20 minute fixation training sessions using a colored (red or blue) light target affects symptoms of light sensitivity, or alters other measurements of the eyes and vision including pupil response.  

This study will involve attending five 1-2 hour study visits, occurring every 1.5 months for 6 months. Study visits will include answering questions about eye and health history, completing surveys, reading letters on an eye chart, having the pupils measured in response to flashes of light, measuring the side vision, measuring eye alignment and in some cases focusing ability. Outside of the study visits, participants will also complete daily 20 minute fixation training sessions for 6 months using a colored (red or blue) light target, completed at home between study visits.

Could this study be right for you?
  • Must be 18 to 80 years old
  • Experienced a head injury 3 or more months ago
  • Current symptoms of light sensitivity
  • Be healthy and have good eye health 
Age Range
18 - 80 years

Impact of A Low Glycemic Index Diet on Blood Pressure and Blood Sugar in Individuals with Spinal Cord Injury

Official Title
Two Birds with One Stone: Impact of A Low Glycemic Index Diet on Postprandial Hypotension and Glucose Metabolism in Individuals with Spinal Cord Injury (FIP)
Purpose

The purpose of this study is to examine the effect of a short-term low glycemic index diet on blood pressure and blood sugar control after eating.

Could this study be right for you?
  • Adults aged 18-65 years old
  • Chronic spinal cord injury
  • Level of injury between C4 and L2
Age Range
18 - 65 years

Assessing Non-invasive Spinal Stimulation to Evaluate its Safety and Effectiveness in Individuals with Spinal Cord Injury

Official Title
ExaStim Upper Limb Pivotal Clinical Validation Study
Purpose

The purpose of this study is to evaluate the safety and effectiveness of ExaStim® transcutaneous spinal stimulation on upper extremity function when applied in combination with physical therapy (PT) and/or occupational therapy (OT).

Participants will be randomized to the stimulation group or a control group. Outcomes will include sensory, motor, and functional tests, as well as questionnaires.

Could this study be right for you?
  • Aged 22 years or older
  • Traumatic chronic spinal cord injury
  • Level of injury between C2-T2
  • No active implanted medical device for electrical stimulation
  • No Botox for 3 months
  • Have a chronic, traumatic SCI (chronic is >12 months since injury, or 6 months if unchanged symptoms)
  • Has some, but limited upper extremity function
  • BMI <40
  • Cannot be pregnant

 

Age Range
22 years and up

A study assessing the impact of a treatment on anxiety and stress in individuals with memory concerns.

Official Title
Treatment of Stress and Anxiety in mild cognitive impairment (MCI)/Mild Alzheimer's Disease and related dementias (ADRD) and their care partners: A Randomized Controlled Trial
Purpose

The purpose of this study is to assess the impact of a treatment on anxiety and stress in individuals with memory concerns and those already with a diagnosis of Mild Cognitive Impairment (MCI), Mild Alzheimer's Disease and related dementias. 

Could this study be right for you?

The primary participant must:
· Be at least 60 years of age
· Have a “care-partner” that is willing to participate in the full program (such as a spouse, child or a good friend)
· NOT have a terminal illness or severe motor impairment
· Be able to use a computer and smartphone and read English at the 6th grade level

The care partner must:
· Be at least 18 years of age
· Be able to use a computer and smartphone and read English at the 6th grade level

Age Range
60 - 99 years

A Study about Retirement from Contact Sports after Concussion

Official Title
Retirement from contact sports after concussion
Purpose

The purpose of this study is to learn about the experiences of children and young adults after they stop playing contact sports due to concussion.

Could this study be right for you?
  • Male and females aged 14-22 years old
  • Retired from contact sports due to prior concussion

Additionally, a parent may participate if their child enrolls. 

Age Range
14 - 22 years

A Study about Brain Imaging on Forming Impressions of Food

Official Title
Decoding Social Perceptions in Naturalistic Contexts
Purpose

The purpose of this study is to examine impressions on foods. This study involves looking at brain activity while you perform simple tasks (judging images of different foods). 

The duration of this study will last 3 hours. 

Could this study be right for you?
  • Free of MRI contradictions
  • No dietary destrictions
  • Normal vison
  • Right handed
Age Range
18 - 35 years