Low Dose Tamoxifen with or without Omega-3 Fatty Acids for Breast Cancer Risk Reduction
Official Title
Phase 2 Study of Low Dose Tamoxifen +/- High Dose Omega-3 Fatty Acids in Overweight Postmenopausal Women at Increased Risk for Breast Cancer
Purpose
This study wants to measure the effects of low dose tamoxifen and omega-3 fatty acids (may also be known as fish oil) on a woman's risk of developing breast cancer.
In this study, half of the participants will be asked to take low dose tamoxifen and the other half low dose tamoxifen with omega-3 fatty acids for about six months. Everyone taking part in the study will be watched carefully for any side effects, which may or may not happen. Tissue and blood collection will be a part of the study participation.
This study is looking for volunteers with an above average risk of developing breast cancer. We will enroll up to 66 participants at institutions across the country. The study lasts about eight months.
Could this study be right for you?
- Postmenopausal
- At increased risk of breast cancer, due to genetic mutation, family history, prior DCIS, LCIS, or atypical hyperplasia
- Overweight or obese (BMI ≥ 25 kg/m2)
- Do not have breast implants
- Seen in Stefanie Spielman Comprehensive Breast Cancer Center in Columbus, OH