A Study to Evaluate the Impact of Eyeliner on Tear Thickness
Researchers at The OSU College of Optometry are seeking individuals who regularly wear eyeliner to investigate the impact on tear thickness.
Participants will be asked to attend two study visits of about one hour each. The participant’s vision and eye health will be evaluated at both study visits, and non-invasive assessments of the tear film will occur as well.
Participants will complete the study over approximately one week. Each visit should take no longer than one hour.
- Must be at least 18 years of age or older
- Individuals who wear eyeliner on their "water line"
Buckeye Concussion Knowledge Survey (BUCKS)
The purpose of this study is to examine health outcomes in former Ohio State University athletes who played a varsity sport during their time at OSU. The objective is to determine whether athletes who sustained a concussion have different health outcomes than those who did not sustain a concussion. Any former OSU varsity athlete can participate in a 20-minute online survey.
- Anyone who has played a varsity sport as an undergraduate student at OSU, and they have now graduated (i.e., OSU athlete alumni). There are no other restrictions in terms of age, sex/gender, type of sport, etc.
Treatment of Chronic Hepatitis C Virus During Pregnancy
This study involves evaluating a medication for hepatitis C in pregnant women.
If you are a pregnant woman with chronic hepatitis C and you join the study, you are consenting to enroll yourself and your baby after he/she is born.
Maternal participants will have 7 visits over approximately 7 months. Infant participants have four visits over approximately the first year of life.
(This is not a complete list)
- Must be 18 - 45 years of age
- Chronic HCV infection of at least 6 months
- Singleton pregnancy at 20 + 0 to 30 + 0 weeks’ gestation
- Documented negative Hepatitis B testing for current infection (negative HBsAg test) prior to enrollment
- If living with HIV, must be on antiretroviral therapy
Exclusion Criteria (not a complete list)
- Plans to relocate away from the study site area in the next 16 months and unable/unwilling to return for study visits
- History of cirrhosis
- Known fetal chromosomal abnormality prior to enrollment
Blood Pressure Health for Black/African American Women Caregivers
The purpose of this study is to determine the feasibility of a group delivered intervention for stress and blood pressure in African American women caregivers.
- Diagnosis of HTN treated with an antihypertensive medication or risk of HTN that includes obesity and high cholesterol
- Age 40 and older
- A caregiver rating of the PLWD of 2 or greater on the Alzheimer’s Dementia-8 scale
- Caregiver provides unpaid care to a PLWD at least 10 hours per week or assists with at least one instrumental activity of daily living
- Self-identifies as Black/African American
- English speaking
- Access to a telecommunications device such as the internet via desktop, laptop/tablet, smartphone, or telephone
Assessing Responses to Exercise in the Heat in Trained Women
The purpose of this research study is to conduct exercise in hot and neutral environments on women who are aerobically trained and resistance trained to characterize and compare responses across physiologic, perceptual, and neurocognitive domains. Our rationale for this investigation is that its completion would provide evidence as to how women of different fitness backgrounds respond to exercise in the heat and how that response is different from exercising in thermoneutral conditions to better describe how the female body tolerates exercise in the heat with implications for those in recreation, competitive sports, and occupation that expands to emergency and military services.
Aerobically Trained: having a measured aerobic capacity in the 80th percentile according to age
Resistance Trained: able to squat 120% and bench press 60% of their body weight.
Unacclimatized: participants had not been consistently exposed to hot conditions (i.e., sauna, hot yoga, etc.) in the past 2 months.
An Intervention Study about Primary Care Algorithms for Early Identification of Young Women with von Willebrand Disease
Researchers at Nationwide Children’s Hospital are seeking volunteers to be a part of a study looking at how to best screen for bleeding disorders in young women.
Participants will be asked to undergo a finger prick blood test and complete questionnaires. If their survey answers suggest they have heavy menses, they will also be asked to have a blood draw on the same day.
- Are 10 to 20 years old
- Have had your first menstrual cycle
An Observational Study of Pregnant Individuals with Glucose Intolerance
The purpose of this study is to learn more about blood sugar levels in the third trimester among women with and without gestational diabetes.
You and your child will be in the study from the time of enrollment through hospital discharge after delivery.
Inclusion criteria:
• Women aged between 18 and 45 years old
• Women with a viable singleton or twin pregnancy between 24 0/7 and 31 6/7 weeks gestation
• Planning to deliver at OSU Wexner Medical Center
Exclusion Criteria:
• Known pregestational diabetes (type 1, type 2, MODY)
• Higher order pregnancy (three or more fetuses)
• Abnormal obstetrical ultrasound suspicious for major congenital abnormality
(Exclusion Criteria varies, please contact Study Coordinator for more information)
An Observation Study to Evaluate Retina Eye Picturing in Women with Preeclampsia
The overall goal is to evaluate whether pictures we take of the retina of the eye can be used to detect preeclampsia and its severity.
Your participation will be from your enrollment visit, until 2-4 months after delivery, which will be no more than 32 weeks.
Inclusion criteria for normal blood pressure healthy pregnant women:
• Women aged 18 years or older
• Pregnant females at enrollment being >= 24 0/7 of pregnancy
• Able and willing to provide consent and willing to conduct the postpartum follow-up
• Normal blood pressure at enrollment
Inclusion criteria for Preeclampsia Pregnancies with severe features:
• Women aged 18 years or older
• Pregnant female at enrollment between 24 0/7 and 33 6/7 of pregnancy
• Able and willing to provide consent and willing to conduct the postpartum follow-up
• All subjects must be Preeclampsia (dangerous high blood pressure in pregnancy) diagnosed.
Exclusion Criteria for both groups:
• Known chromosomal, genetic, major malformations, fetal demise.
• Past medical history of hypertension >5 years, pre-gestational diabetes, or know retinal disease
• Pregnant for twin, triplets or higher
• Participating in another intervention study that influences the outcomes in this study.
A Study Evaluating Ketorolac Dosing and Pain Management After C-section Delivery
The purpose of this study is to compare the use of morphine milligram equivalents (MME) in the first 24 hours of post-op C-Section delivery in patients getting a single dose of 30 mg ketorolac injected through the vein vs. 60 mg ketorolac injected through the vein in the operating room after the end of surgery.
Participation in this study starts from enrollment until being discharged from the hospital.
INCLUSION:
• Pregnant women aged between 18 to 45 years old
• C-Section as the planned delivery process
• Regional anesthesia (Spinal, Epidural, Combined Spinal Epidural)
EXCLUSION:
• Known allergy or adverse reaction to NSAIDs, aspirin, or ketorolac
• Patients with peptic ulcer disease, preexisting kidney or liver disease
• Patients with bleeding problem
• Acute or chronic pain disorder
• General anesthesia
• Opioid use disorder
• Emergent Cesarean delivery
• Active asthma
• Patients weighing <50 kg
An Observation Study to Examine the Effectiveness of Nifedipine
The purpose of this study is to compare the effectiveness of long-acting Nifedipine XL 60mg daily to 30mg twice daily among women admitted with hypertensive disorders of pregnancy and severe blood pressures. Participation for the duration of the study lasts 48 hours.
Inclusion Criteria: • Women aged 18-45 years old • Viable single or twin intrauterine pregnancy between 22 0/7 and 33 5/7 weeks gestation • Women with a hypertensive disorder of pregnancy and are undergoing expectant management (spontaneous labor) for a diagnosis of preeclampsia • Patient has already been started on 30mg Nifedipine XL by their primary OB provider and has been recommended to increase the daily dose to 60mg Exclusion Criteria: • Known allergy or poor reaction to Nifedipine or any medical condition where Nifedipine should not be used in ones treatment, such as galactose intolerance, severe GI stricture, and GI hypomotility disorder. • Participation in another trial without prior approval • Currently receiving a daily dose of Nifedipine XL of 60mg or greater • Continuation of alternate long-acting anti-hypertensive medication on admission • Triplet or higher order pregnancy (Exclusion Criteria still varies, please contact Study Coordinator for more information).