Breathing Training Program for Breast Cancer Survivors with Obesity

Official Title
Reducing exercise intolerance through inspiratory muscle training in obese breast cancer survivors (IMOCS)
Purpose

The purpose of this study is to better understand why some survivors of breast cancer have difficulty exercising. We also want to learn if breathing exercises can make it easier to tolerate exercise. 

Could this study be right for you?
  • Breast Cancer Survivor
  • Completed treatment within 6 months–5 years
  • Have obesity, defined as body mass index between 30-50 kg/m2
  • Can exercise independently
Age Range
18 years and up

Understanding Patient Experiences of Gestational Diabetes

Official Title
A Multi-Actor Examination of Gestational Diabetes Mellitus (GDM)
Purpose

This study aims to examine the experience of people who have been diagnosed or are currently living with gestational diabetes, including how they manage and make sense of their diagnosis. 

Could this study be right for you?
  • Aged 18 years or older
  • Must live in the state of Ohio
  • Must be currently pregnant and have been diagnosed with gestational diabetes OR must have been diagnosed with gestational diabetes during a recent pregnancy (within the last 12 months)
Age Range
18 years and up

Buckeye Concussion Knowledge Survey (BUCKS)

Official Title
BUckeye Concussion Knowledge Survey (BUCKS)
Purpose

The purpose of this study is to examine health outcomes in former Ohio State University athletes who played a varsity sport during their time at OSU. The objective is to determine whether athletes who sustained a concussion have different health outcomes than those who did not sustain a concussion. Any former OSU varsity athlete can participate in a 20-minute online survey.

Could this study be right for you?
  • Anyone who has played a varsity sport as an undergraduate student at OSU, and they have now graduated (i.e., OSU athlete alumni). There are no other restrictions in terms of age, sex/gender, type of sport, etc.
Age Range
18 years and up

Treatment of Chronic Hepatitis C Virus During Pregnancy

Official Title
Safety, Tolerability, and Outcomes of Velpatasvir/SofosbuviR in Treatment of Chronic Hepatitis C Virus during Pregnancy (STORC), pregnant woman
Purpose

This study involves evaluating a medication for hepatitis C in pregnant women. 

If you are a pregnant woman with chronic hepatitis C and you join the study, you are consenting to enroll yourself and your baby after he/she is born.

Maternal participants will have 7 visits over approximately 7 months. Infant participants have four visits over approximately the first year of life.

Could this study be right for you?

(This is not a complete list)  

- Must be  18 - 45 years of age

Chronic HCV infection of at least 6 months

- Singleton pregnancy at 20 + 0 to 30 + 0 weeks’ gestation

Documented negative Hepatitis B testing for current infection (negative HBsAg test) prior to enrollment

If living with HIV, must be on antiretroviral therapy

 

Exclusion Criteria (not a complete list)

Plans to relocate away from the study site area in the next 16 months and unable/unwilling to return for study visits

History of cirrhosis

Known fetal chromosomal abnormality prior to enrollment

Age Range
18 - 45

Blood Pressure Health for Black/African American Women Caregivers

Official Title
Addressing the double jeopardy of stress and hypertension among African American female caregivers of persons living with Alzheimer’s disease and related dementias (R21)
Purpose

The purpose of this study is to determine the feasibility of a group delivered intervention for stress and blood pressure in African American women caregivers.

Could this study be right for you?
  • Diagnosis of HTN treated with an antihypertensive medication or risk of HTN that includes obesity and high cholesterol
  • Age 40 and older
  • A caregiver rating of the PLWD of 2 or greater on the Alzheimer’s Dementia-8 scale
  • Caregiver provides unpaid care to a PLWD at least 10 hours per week or assists with at least one instrumental activity of daily living
  • Self-identifies as Black/African American
  • English speaking
  • Access to a telecommunications device such as the internet via desktop, laptop/tablet, smartphone, or telephone
Age Range
40 and up

Assessing Responses to Exercise in the Heat in Trained Women

Official Title
Assessing Responses to Exercise in the Heat in Trained Women
Purpose

The purpose of this research study is to conduct exercise in hot and neutral environments on women who are aerobically trained and resistance trained to characterize and compare responses across physiologic, perceptual, and neurocognitive domains. Our rationale for this investigation is that its completion would provide evidence as to how women of different fitness backgrounds respond to exercise in the heat and how that response is different from exercising in thermoneutral conditions to better describe how the female body tolerates exercise in the heat with implications for those in recreation, competitive sports, and occupation that expands to emergency and military services.

Could this study be right for you?

Aerobically Trained: having a measured aerobic capacity in the 80th percentile according to age

Resistance Trained: able to squat 120% and bench press 60% of their body weight.

Unacclimatized: participants had not been consistently exposed to hot conditions (i.e., sauna, hot yoga, etc.) in the past 2 months.

Age Range
18 - 35

An Intervention Study about Primary Care Algorithms for Early Identification of Young Women with von Willebrand Disease

Official Title
Primary Care Algorithms for Early Identification of Young Women with von Willebrand Disease
Purpose

Researchers at Nationwide Children’s Hospital are seeking volunteers to be a part of a study looking at how to best screen for bleeding disorders in young women.

Participants will be asked to undergo a finger prick blood test and complete questionnaires. If their survey answers suggest they have heavy menses, they will also be asked to have a blood draw on the same day.

Could this study be right for you?
  • Are 9 to 21 years old
  • Have had your first menstrual cycle
Age Range
9 - 21

An Observational Study of Pregnant Individuals with Glucose Intolerance

Official Title
The use of continuous glucose monitors among pregnant individuals with various degrees of glucose intolerance: An observational cohort study
Purpose

The purpose of this study is to learn more about blood sugar levels in the third trimester among women with and without gestational diabetes.

You and your child will be in the study from the time of enrollment through hospital discharge after delivery.

Could this study be right for you?

Inclusion criteria:
• Women aged between 18 and 45 years old
• Women with a viable singleton or twin pregnancy between 24 0/7 and 31 6/7 weeks gestation
• Planning to deliver at OSU Wexner Medical Center

Exclusion Criteria:
• Known pregestational diabetes (type 1, type 2, MODY)
• Higher order pregnancy (three or more fetuses)
• Abnormal obstetrical ultrasound suspicious for major congenital abnormality
(Exclusion Criteria varies, please contact Study Coordinator for more information)

Age Range
18 and up

An Observation Study to Evaluate Retina Eye Picturing in Women with Preeclampsia

Official Title
Remote monitoring of retina vasculature in women with preeclampsia: novel biomarker for disease severity
Purpose

The overall goal is to evaluate whether pictures we take of the retina of the eye can be used to detect preeclampsia and its severity.

Your participation will be from your enrollment visit, until 2-4 months after delivery, which will be no more than 32 weeks.

Could this study be right for you?

Inclusion criteria for normal blood pressure healthy pregnant women:
• Women aged 18 years or older
• Pregnant females at enrollment being >= 24 0/7 of pregnancy
• Able and willing to provide consent and willing to conduct the postpartum follow-up
• Normal blood pressure at enrollment
Inclusion criteria for Preeclampsia Pregnancies with severe features:
• Women aged 18 years or older
• Pregnant female at enrollment between 24 0/7 and 33 6/7 of pregnancy
• Able and willing to provide consent and willing to conduct the postpartum follow-up
• All subjects must be Preeclampsia (dangerous high blood pressure in pregnancy) diagnosed.

Exclusion Criteria for both groups:
• Known chromosomal, genetic, major malformations, fetal demise.
• Past medical history of hypertension >5 years, pre-gestational diabetes, or know retinal disease
• Pregnant for twin, triplets or higher
• Participating in another intervention study that influences the outcomes in this study.

Age Range
18 and up

A Study Evaluating Ketorolac Dosing and Pain Management After C-section Delivery

Official Title
Dosing of Ketorolac Impacts post-cesarean paiN manaGement (KING): A Randomized Controlled Trial
Purpose

The purpose of this study is to compare the use of morphine milligram equivalents (MME) in the first 24 hours of post-op C-Section delivery in patients getting a single dose of 30 mg ketorolac injected through the vein vs. 60 mg ketorolac injected through the vein in the operating room after the end of surgery.

Participation in this study starts from enrollment until being discharged from the hospital.

Could this study be right for you?

INCLUSION:
• Pregnant women aged between 18 to 45 years old
• C-Section as the planned delivery process
• Regional anesthesia (Spinal, Epidural, Combined Spinal Epidural)
EXCLUSION:
• Known allergy or adverse reaction to NSAIDs, aspirin, or ketorolac
• Patients with peptic ulcer disease, preexisting kidney or liver disease
• Patients with bleeding problem
• Acute or chronic pain disorder
• General anesthesia
• Opioid use disorder
• Emergent Cesarean delivery
• Active asthma
• Patients weighing <50 kg

Age Range
18 and up