Official Title AN OBSERVATIONAL, LONGITUDINAL, PROSPECTIVE, LONG-TERM REGISTRY OF PATIENTS WITH HYPOPHOSPHATASIA

Purpose

The purpose of this registry is to collect information about Hypophosphatasia (HPP), a rare bone disorder characterized by the abnormal development of bones and teeth. This long-term registry will collect and store patient medical information, and other related information to use in medical research. the registry may help researchers better understand the condition and learn more about patients who have HPP. This data may help other people with HPP in the future.

Could this study be right for you?

• 18 years of age or older
• Been diagnosed with Hypophosphatasia (HPP) - a rare genetic disorder characterized by the abnormal development of bones and teeth.
• Not participating in another Alexion-sponsored clinical trial

Age Range

18 and up

Official Title The Effects of Dry Needling on Patients with Knee Pain

Purpose

This study is testing the effectiveness of "dry needling" for pain management and on muscle strength and leg function for those with knee pain. Dry needling consists of small, monofilament needles that are administered directly into the tissue and manipulated to make the muscle relax for pain relief. This technique is used to treat dysfunctions in skeletal muscle and connective tissue to help diminish pain, reduce impairments of body structure and restore function.

Could this study be right for you?

Eligibility Criteria:

• Ages 18-40
• Referred for physical therapy
• Presence of knee pain (for at least 3 months) around the knee cap (patella) during ascending/descending stairs, squatting, and/or running.

Age Range

18 and up

Official Title The Ohio State Lupus, Vasculitis and Glomerulonephritis Registry

Purpose

The purpose of the OSU Lupus and Vasculitis Registry is to obtain clinical and laboratory information about lupus and vasculitis and glomerulonephritis.

Could this study be right for you?

Patients at the Ohio State University Rheumatology and Lupus Clinic with one of the following diagnoses who are ages 18 years of age and older:

• Systemic lupus erythematosus
• Discoid lupus
• Mixed connective tissue disorder
• Undifferentiated connective tissue disorder
• Wegener’s granulomatosus
• Microscopic polyangiitis
• Henoch-Schonlien Purpura
• Takayasu’s arteritis
• Giant cell/temporal arteritis
• Churg-Strauss vasculitis
• Other vasculitides
• IgA nephropathy
• Anti-GBM GN
• Membranous GN
• Minimal Change Disease
• Focal Segmental Glomerulosclerosis

Age Range

18 and up