The purpose of this 28-week study to investigate the effects and safety of a medication in participants with Center Involving Diabetic Macular Edema (CI-DME). .
- 18 years and older - Macular edema associated with diabetic retinopathy (DR) - Diagnosis of diabetes mellitus (DM)
We are looking at parts of the cells in our bodies (called mitochondria). Mitochondria give our cells energy and help them stay healthy. People with diabetes have mitochondria which do not work as well as the mitochondria in people without diabetes.
In this study, we want to see if exercise (cardiac rehabilitation) will cause your mitochondria to work better. Using a magnetic resonance imaging (MRI) machine, we can measure how much your cardiac rehabilitation has helped your mitochondria. We will be looking at your leg muscle and the mitochondria in those cells.
In this study, we hope to show that we can help those with diabetes by making their mitochondria work better using things like exercise. We will be looking for people who are beginning cardiac rehabilitation, some with and some without diabetes.
- 18 yrs and older
- Have been referred for cardiac rehabilitation
- Are able to have an MRI (study coordinator can screen you for this)