This study aims to examine the experience of people who have been diagnosed or are currently living with gestational diabetes, including how they manage and make sense of their diagnosis.
- Aged 18 years or older
- Must live in the state of Ohio
- Must be currently pregnant and have been diagnosed with gestational diabetes OR must have been diagnosed with gestational diabetes during a recent pregnancy (within the last 12 months)
The purpose of this study is to examine how whole wheat bread lowers blood glucose levels by improving gut health and inflammation.
- Are at least 25 pounds overweight
- Are a non-smoker
- No medications that affect blood sugar, blood pressure, or inflammation
The purpose of this study is to examine the effects of glucose levels on atrial fibrillation episodes in people with diabetes and history of atrial fibrillation.
The duration of the study lasts 6 months.
- Participants diagnosed with type 2 diabetes mellitus
- Body mass index between 25 and 45 kg/m2
- Insulin use at least 10 units per day or more than 1 glucose lowering medication with a hemoglobin A1c greater than 7%
- ICM placement
- Paroxysmal atrial fibrillation (irregular heartbeat that goes back to normal after a week) or atrial fibrillation ablation (procedure to treat irregular heartbeat) within 30 days
The purpose of this study is to lower the rate of type 2 diabetes in rural Appalachia youth due to obesity and/or being overweight. Our long-term goal is to improve the health of underserved, high-risk youth.
This study will test the effectiveness of the Mentored Planning to be Active + Family on physical activity outcomes and health outcomes among rural Appalachian middle school aged youth suffering from either overweight or obesity.
We have local high school-aged teen mentors work closely with middle school youth to increase social support, self-efficacy, and self-regulation skills to sustain physical activity and improve health before the children enter high school.
The peer mentoring is followed by a 6-month family reinforcement program.
Some parents will provide child assessment data of perceived child physical activity behaviors and child health.
- Child has access to a computer or tablet device at home for virtual mentoring sessions/meetings
- Child suffers from overweight or obesity - does not need to be under the care of a health care professional for this condition
- Child and Parent able to participate read English at a 4th grade level.
- Family not expected to move from rural Appalachia within the 18 months.
The purpose of this study is to improve hemoglobin A1c levels in patients with type 2 diabetes experiencing food insecurity.
The study will examine the effects of a produce referral program alone and in combination with other interventions. Our research is designed to develop a deeper understanding of how to provide patients with type 2 diabetes that are experiencing food insecurity with the resources, skills, and education to manage their health and social needs.
- Age 18 years and older
- Type 2 diabetes based on American Diabetes Association Criteria
- Hemoglobin A1c level > 7.5%
- Worried about running out of food before you have money to buy more
The purpose of this study is to find out if taking one medication Diovan (valsartan) or a combination of two medications (valsartan and sacubatril) in one pill called Entresto, will improve prediabetes in Blacks /African Americans over the course of 6 months. We will also look for changes in blood pressure and blood vessel stiffness throughout the course of the study in order to better understand how these medications may impact prediabetes.
Inclusion Criteria: - African American aged 18-65 years old - History of impaired fasting glucose - Impaired glucose tolerance - A1c 5.7-6.4% or other risk factors for diabetes Exclusion Criteria: - Type 2 diabetes - Systolic blood pressure greater than 150/100 or medications to lower your blood pressure - Systolic blood pressure less than 100/60 - Steroid use - Hyperkalemia (high potassium levels)
The aim of this study is to improve mood and diabetes-related outcomes for those with type 2 diabetes mellitus (T2DM) AND symptoms of depression. The present study will examine the effect of mindfulness-based cognitive therapy (MBCT) on symptoms of depression and diabetes.
Your participation in this study will last 8 weeks.
You may qualify if:
• You are between the ages 18-75
• You have type 2 diabetes
• You are feeling symptoms of depression
The purpose of this research study is to better understand the role of fat tissue, how cells in fat tissue communicate, and determine what signals specific cells use to cause inflammation and insulin resistance during weight gain. This may help researchers better understand the process that happens in Type 2 Diabetes.
As a result, through the course of six--nine weeks, participants will be asked to gain at least 10% of their starting body weight. A dietitian will meet with participants to give advice to help with meeting the study weight gain goals, as well as provide additional meal vouchers and supplemental shakes as needed. Following the study, participants will receive guidance how to lose the weight they've gained if they would like to do that.
You may be eligible if you:
- Are 18-60 years of age
- Are lean; Have a BMI 18-24.9 kg/m2 (*see link below for calculating your BMI --Body Mass Index)
- Have healthy levels of cholesterol and triglycerides (These will be tested at screening)
- Are a non-smoker
- Are non-diabetic
- Are free of chronic illness
- Are not pregnant or breastfeeding
*If you want to calculate your BMI https://www.cdc.gov/healthyweight/assessing/bmi/adult_bmi/english_bmi_c…
- Fasting triglycerides > 150 mg/dL or nonfasting triglycerides ˃ 250 mg/dl
- LDL-Cholesterol level > 150 mg/dL,
- Presence of significant anemia (hemoglobin <10.0 gm/dL),
- Currently or planning to take blood thinners ,
- Current smokers
- Have taken steroids or anti-inflammatory meds for >6 months in the last 6 months
- >10% body weight loss within 3 months of enrollment
*Other exclusions may apply
This research study is for those who have nonalcoholic steatohepatitis (NASH) (meaning your liver is swollen and damaged because of a buildup of fat in your liver) and some liver fibrosis (which is damaged and scarred liver tissue). Because of your condition, you may be eligible for a research study on an investigational drug for your condition. The Regenerate Study will assess the safety and effectiveness of the investigational medication obeticholic acid (OCA) compared to placebo in delaying specific medical conditions or health related issues that can occur in patients with nonalcoholic steatohepatitis (NASH) (meaning your liver is swollen and damaged because of a buildup of fat in your liver) and some liver fibrosis (which is damaged and scarred liver tissue).
- Age 18 or older
- Diagnosed with Stage 2 or 3 NASH (nonalcoholic steatohepatitis--meaning your liver is swollen and damaged because of a buildup of fat in your liver) and some liver fibrosis (which is damaged and scarred liver tissue).
If you are eligible and decide to take part in this research study, you will need to complete 1 or 2 screening visits to see if you are eligible to participate in the study. Once the study doctor determines you can participate in the study, you will be asked to come back to the clinic 8 times (for the Month 0 [Day 1] Visit, the Month 1 Visit, the Month 3 Visit, and then every 3 months) for the first 18 months you are in the study and then 2 times per year (every 6 months) for each additional year you are in the study.
The purpose of this 28-week study to investigate the effects and safety of a medication in participants with Center Involving Diabetic Macular Edema (CI-DME). .
- 18 years and older - Macular edema associated with diabetic retinopathy (DR) - Diagnosis of diabetes mellitus (DM)