Research Study on Light Sensitivity after Head Injury
Researchers at The Ohio State University College of Optometry are seeking individuals with a recent history of head trauma who are experiencing light sensitivity. The goal of this study is to determine if daily 20 minute fixation training sessions using a colored (red or blue) light target affects symptoms of light sensitivity, or alters other measurements of the eyes and vision including pupil response.
This study will involve attending five 1-2 hour study visits, occurring every 1.5 months for 6 months. Study visits will include answering questions about eye and health history, completing surveys, reading letters on an eye chart, having the pupils measured in response to flashes of light, measuring the side vision, measuring eye alignment and in some cases focusing ability. Outside of the study visits, participants will also complete daily 20 minute fixation training sessions for 6 months using a colored (red or blue) light target, completed at home between study visits.
- Must be 18 to 80 years old
- Experienced a head injury 3 or more months ago
- Current symptoms of light sensitivity
- Be healthy and have good eye health
Tear Lipid Layer Thickness with and without Scleral Lenses
The purpose of this study is to explore the tear lipid layer thickness changes in participants while wearing and not wearing a scleral lens.
Inclusion criteria:
- Age – 18 or older
- Good general health (defined by medication use that has not changed within the last month and the absence of medical conditions or treatments that are deemed confounding to the data as determined by the PI)
- Ability to give informed consent
- Willing to spend time for the study
- Willing to wear a scleral contact lens during the study visit
- Either gender
- Any racial or ethnic origin
Habitual contact lens wearers must refrain from lens wear the day of the study visit. Artificial tears must not be used for two days before the screening visit and data collection visit.
Exclusion criteria:
- Active ocular inflammation
- Use of any ocular prescription medication (such as but not limited to, glaucoma medications, anti-inflammatory eye drops and Restasis or Xiidra) used within 14 days of the screening visit or started prior to the measurement visit(s).
- Currently having punctal plugs inserted in lacrimal puncta
Exclusion Criteria varies, please contact Study Coordinator.
Contact Lens Study in Adults with Presbyopia
The purpose of this study is to learn about the wear experience of adults who dropped out of contact lens wear once they became presbyopic.
- Adults who have dropped out of contact lens wear
- Ability to attend 3 visits over the course of 5 weeks
- Satisfy all other study eligibility and exclusion criteria
Eye Tracking of Pitched Balls
The purpose of this study is to compare eye and head movement behavior when baseball batters swing at (but do not hit) an approaching ball and when batters judge the height above the ground at which an approaching ball would reach had it arrived at the batter.
- Must have visual acuity of 20/20 in each eye
- No eye turn
- Depth perception of 60 seconds of arc
- Must have played organized baseball or softball at the high school level or above within the last 10 years
A Study about a FDA Approved Contact Lenses for Management of Myopia
The purpose of this study is to evaluate if FDA approved contact lenses can reduce the progression of nearsightedness in children. Children who participate in this 4-year study will be asked to wear the study provided contact lenses at least 6 days a week and be willing to attend visits at The OSU College of Optometry one month after starting treatment and every six months thereafter. Visits will include a comprehensive eye exam and contact lens fitting at no cost.
- Children ages 8 to 12 years old.
- No previous medication or contact lenses related to myopia control.
- Glasses and/or contact lens prescription between -0.75 and -4.00 diopters.
- Satisfy all other study eligibility criteria.
Determining the Best Glasses Prescription for Children with Down Syndrome
The purpose of this study is to examine whether we can use an instrument that measures how the eye focuses light to determine the best glasses prescription.
- Children with Down syndrome age 5 to 17 years
- Able to do vision tests by naming or matching shapes or letters
- Able to look at lights for short periods of time
- No nystagmus (uncontrolled eye movements when trying to look at things)
- Safe to dilate the eyes - we will screen medical history, eye health, and allergies to determine this
- No scars on the front of the eye
- No cataracts
- No eye diseases like glaucoma or retinal problems
Evaluation of Hand/Eye Coordination with Multifocal Contact Lenses Compared to Progressive Addition Spectacles
This study is looking to compare the use of multifocal contact lenses to progressive-addition (no-line bifocal) glasses. Participants will be asked to perform a hand/eye coordination task once while wearing glasses, and once while wearing contact lenses.
The duration of the study lasts 1 hour.
- Must currently have presbyopia (unable to focus on objects at near).
- Must have up-to-date pair of progressive-addition glasses (addition power of +1.50 D or higher), worn for at least 2 weeks prior to screening visit.
- Must be a wearer of multifocal contact lenses.
- Meet other study eligibility criteria.
A Study about Eye Teaming, Focusing Ability and Quality of Life
The purpose of this study is to assist in development of a new quality of life survey that can be used to learn more about how eye teaming, focusing ability and eye movement problems affect a child’s life.
- Children experiencing eye teaming, focusing, and eye movement problems (with recent concussion or non-concussed)
- Children with amblyopia (lazy eye) are excluded
A Randomized Trial to Evaluate Sequential vs Simultaneous Spectacles plus Patching for Amblyopia in Children 3 to <13 Years Old
The purpose of this study is to evaluate if treating amblyopia (lazy eye) with glasses and patching at the same time improves vision as well as treating amblyopia first with glasses and then with patching, if needed.
- Visual acuity in the amblyopic eye between 20/40 and 20/200
- No previous treatment for amblyopia, including glasses or contact lenses
- Amblyopia (lazy eye) in one eye
Tear Film in Children Study
The goal of this study is to describe the risks associated with overnight orthokeratology contact lens wear in children by identifying corneal and tear film changes. The study aims to describe and compare the tear film components in a pediatric sample wearing orthokeratology contact lenses (used to change the shape of the cornea), soft contact lenses, or glasses. Additionally, the study aims to compare the corneal thickness profile in a pediatric sample wearing orthokeratology contact lenses, soft contact lenses, or glasses.
This study requires one visit only. The overall timeline from subject recruitment to study completion is dependent upon subject and examiner availability and scheduling. As long as no changes occur to subject eligibility between initial recruitment and the study visit, there is some flexibility with timing.
- Near-sighted prescription between -1.00D and -6.00D
- Current correction with glasses, soft contact lenses, or overnight orthokeratology contact lenses
- Has been wearing current correction for 6 months or longer
- Good eye and overall health