A Study to Evaluate the Impact of Eyeliner on Tear Thickness
Researchers at The OSU College of Optometry are seeking individuals who regularly wear eyeliner to investigate the impact on tear thickness.
Participants will be asked to attend two study visits of about one hour each. The participant’s vision and eye health will be evaluated at both study visits, and non-invasive assessments of the tear film will occur as well.
Participants will complete the study over approximately one week. Each visit should take no longer than one hour.
- Must be at least 18 years of age or older
- Individuals who wear eyeliner on their "water line"
Evaluation of Hand/Eye Coordination with Multifocal Contact Lenses Compared to Progressive Addition Spectacles
This study is looking to compare the use of multifocal contact lenses to progressive-addition (no-line bifocal) glasses. Participants will be asked to perform a hand/eye coordination task once while wearing glasses, and once while wearing contact lenses.
The duration of the study lasts 1 hour.
- Must currently have presbyopia (unable to focus on objects at near).
- Must have up-to-date pair of progressive-addition glasses (addition power of +1.50 D or higher), worn for at least 2 weeks prior to screening visit.
- Must be a wearer of multifocal contact lenses.
- Meet other study eligibility criteria.
A Study about Eye Teaming, Focusing Ability and Quality of Life
The purpose of this study is to assist in development of a new quality of life survey that can be used to learn more about how eye teaming, focusing ability and eye movement problems affect a child’s life.
- Children experiencing eye teaming, focusing, and eye movement problems (with recent concussion or non-concussed)
- Children with amblyopia (lazy eye) are excluded
A Randomized Trial to Evaluate Sequential vs Simultaneous Spectacles plus Patching for Amblyopia in Children 3 to <13 Years Old
The purpose of this study is to evaluate if treating amblyopia (lazy eye) with glasses and patching at the same time improves vision as well as treating amblyopia first with glasses and then with patching, if needed.
- Visual acuity in the amblyopic eye between 20/40 and 20/200
- No previous treatment for amblyopia, including glasses or contact lenses
- Amblyopia (lazy eye) in one eye
Tear Film in Children Study
The goal of this study is to describe the risks associated with overnight orthokeratology contact lens wear in children by identifying corneal and tear film changes. The study aims to describe and compare the tear film components in a pediatric sample wearing orthokeratology contact lenses (used to change the shape of the cornea), soft contact lenses, or glasses. Additionally, the study aims to compare the corneal thickness profile in a pediatric sample wearing orthokeratology contact lenses, soft contact lenses, or glasses.
This study requires one visit only. The overall timeline from subject recruitment to study completion is dependent upon subject and examiner availability and scheduling. As long as no changes occur to subject eligibility between initial recruitment and the study visit, there is some flexibility with timing.
- Near-sighted prescription between -1.00D and -6.00D
- Current correction with glasses, soft contact lenses, or overnight orthokeratology contact lenses
- Has been wearing current correction for 6 months or longer
- Good eye and overall health
A Study About the Development of Learning in African-American/Black Children
The purpose of this study is to investigate the early development of attention, learning, and memory during childhood. Participation in this study includes 4, 90-minute-long visits to the lab per year. During these visits, your child will play 2-3 fun, computerized games. These games are designed to assess various aspects of their cognitive ability.
The duration of the study will last 4 years.
Eligibility Criteria:
- African-American/Black children who are 4 years old
A Study to Examine Atropine for the Reduction of Nearsightedness (The CHAPERONE Study)
The purpose of this study to test the safety and effectiveness of atropine 0.1% and atropine 0.01% eye solutions. These drugs are being tested to see if they slow the worsening of nearsightedness. Children who participate in this study will be asked to use their assigned study medication every night and willing to attend visits at The Ohio State University of Optometry 1 month after starting treatment. These visits will continue for 6 months until the duration of the study ends. This study will take place over a 4-year time period.
· Children aged 3 to < 13 years old. · No previous use of medications related to myopia control. · Glasses and/or contact lens prescription between -1.00 and -6.00 diopters. Interested guardians who believe their child may be eligible should contact study coordinators to further determine eligibility
Reviewing and Evaluating Resources Related to Dizziness and Home Based Therapies
The purpose of this study is to look at a web-based tool on the topic of dizziness so that we can create resources for teaching patients about causes of dizziness and home-based therapies. We are recruiting patients with dizziness and/or general volunteers to review the web-based tool and then provide feedback which will then be used to help update requirements for the educational tool. This study will take about 20-30 minutes of your time to review a website and complete a survey. If you decide to also participate in the discussion, it will take about 20-30 more minutes.
- Participants must be 18 years or older - able to speak and read English at an eighth-grade level or above - be willing and able to participate
A study for children with nearsightedness
Is your child nearsighted?
Nearsightedness, or myopia, is a condition that results in blurry vision when looking at distant objects.
Myopia happens when the eyeball grows too long or the cornea (the clear front cover of the eye) is too curved.
As a result, light entering the eye is not focused correctly. While glasses and contact lenses can help a person with myopia see clearly, they do not address the underlying stretching of the eye.
Myopia detected in young children tends to increase through the school years . As myopia progresses, it can increase the risk of retinal detachment, cataracts, myopia maculopathy and even blindness. To date, FDA has not approved any drug therapies for reducing myopia progression.
This is why researchers are working to develop new medications and technologies that may help children and teens with this condition. The CHAPERONE Study is a research study testing the safety and effectiveness of microdosed atropine eye solution to see if it slows the progression of myopia in children.
- Is your child between 3-12 years old?
- Does your child need glasses to see distant objects?
- Is your child able to go to periodic visits at the study clinic to check his/her vision and overall eye health over a 4-year period (11 scheduled visits will be required)?
- Are you available to speak with study staff by phone periodically between your child’s clinic visits to review your child’s experience using study medication?
This study is not for children who have:
- Used atropine or other myopia drug therapies
- Had prior eye surgery
- A systemic disease or condition that can affect their vision
A TBI (Traumatic Brain Injury) and Vision Study
The goal of this study is to determine whether measurements of the pupil’s reaction to light are associated with the presence of vision problems which are commonly observed after head trauma.
This study will compare how the pupil reacts to a flash of light (like a camera flash) in those with and without vision problems after TBI to see if this measure could be a widely available screener for vision problems.
If you are eligible and participate, you will be asked to read letters and follow targets with your eyes. You will also have your pupil reflexes measured with a short flash of light (similar to a camera flash).
- Be at least 7 years of age
- Have a history of head trauma, such as concussion