Official Title

Associations between Race, Gut Microbiota-Metabolites, and Long-Term Symptom Toxicity in African Americans and Caucasian Americans Colorectal Cancer Survivors

Purpose

The purpose of this study is to learn about the associations of symptoms such as fatigue, depression, and gastrointestinal distress including constipation, abdominal pain, and diarrhea with stool microbiomes and metabolites in patients with colorectal cancer. We will compare the associations of symptoms with microbiomes among colorectal cancer patients and healthy patients. You will be asked to complete several surveys that ask questions about your dietary habits, your health history, your social demographics, and your symptoms. You will also be asked to collect a stool sample with an at-home stool sample collection kit that will be provided to you.

Could this study be right for you?

• Diagnosed with stage I-IV colorectal cancer (ICD-10 C18, C19 and C20) OR Healthy.
• 18+ years of age at time of diagnosis.
• Able to communicate in English and provide consent.
• African American OR White.
• Not currently in cancer treatment.
• No current ostomy.
• No chronic bowel disorders (e.g., irritable bowel syndrome).
• No diagnosis of functional GI disorders.
• No food allergies or dietary restrictions.
• No use of probiotics or antibiotics within the past two months prior to fecal collection.
• No significant cognitive or developmental delay that precedes cancer diagnosis (e.g., down syndrome, autism spectrum disorder).

Age Range

18 years and up

Official Title

Impulsivity Domains and Subjective Response

Purpose

The purpose of this study is to examine the degree to which different ways of thinking and decision making – measured using computer tasks and questionnaire – relate to how people feel after a dose of alcohol. By doing this study, we hope to learn about the relationships between decision making and responses to alcohol.

Could this study be right for you?

Inclusion criteria include:

1. Ages 21-25
2. Report drinking to an estimated BAC > 80mg% at least once in the past 30 days 
3. Report drinking at least twice weekly in the past 30 days 
4. English language Fluency

Exclusion criteria include:

1. Any serious medical problems (i.e., liver disease, cardiac abnormality, pancreatitis, diabetes, neurological problems, gastrointestinal disorders, abnormal kidney function)
2. Body weight < 110 or > 210 pounds
3. Current medical or psychiatric condition requiring medication for which alcohol consumption is contraindicated
4. Lifetime history of schizophrenia or other psychotic disorder
5. Substance Use Disorder other than alcohol

Exclusion Criteria varies, please contact Study Coordinator. 

Age Range

21 - 25 years

Official Title

PRagmatic EValuation of evENTs And Benefits of Lipid-lowering in oldEr adults

Purpose

The purpose of PREVENTABLE is to learn if taking a statin could help older adults live well for longer by preventing dementia, disability, or heart disease. The duration of the study will last 5 years. 

Could this study be right for you?

Inclusion Criteria:

• Community-dwelling adults
• Age ≥75 years
• English or Spanish as primary language

 

Exclusion Criteria:

• Clinically evident cardiovascular disease defined as prior myocardial Infarction (MI), prior stroke, prior revascularization procedure, or a secondary prevention indication for a statin (clinician determined)
• Hospitalization for a primary diagnosis of heart failure in the prior 12 months (Note: History of heart failure in the absence of recent hospitalization or clinically evident cardiovascular disease is not an exclusion)
• Dementia (clinically evident or previously diagnosed)
• Dependence in any Katz Basic Activities of Daily Living [ADL] (with the exception of urinary or bowel continence)
• Severe hearing impairment (preventing phone follow up)
• Unable to talk (preventing phone follow up)

Exclusion Criteria varies, please contact Study Coordinator for more information. 

Age Range

75 years and up

Official Title

The Tree of Hope: A Method to Reduce Burnout, Improved Hope and Increase Resilience

Purpose

The purpose of this study is to improve the sense of hope and build resilience through creating one’s Tree of Hope. This study is being done because we see that today’s environment is quite stressful and this can lead to people feeling less hopeful in their present and the future. 

 

Could this study be right for you?

• At least 18 years old 
• Able to read and understand English 
• Healthy people and patients will be eligible for this research study 
• Participants will be eligible even if they are not seen at OSU for their care.
• We will not abstract any data from electronic health records. Patients will complete a survey that asks them questions about their health conditions

Exclusion Criteria

• Any physical or mental condition that the principal investigator considers as impacting the ability of the patient to participate in the research study. Examples include visual or hearing impairment, arthritis, weakness or other medical problem that impairs their ability to write. 

Age Range

18 years and up

Official Title

Uncertainty and Firearms: Obtaining Secure Storage (UFOS)

Purpose

The purpose of this study is to examine whether fear of uncertainty plays a role in home safety practices among firearm owners who are currently or have recently served in the U.S. military.

Could this study be right for you?

• Currently serving in any Branch or Component of the U.S. military, or were discharged from the U.S. military within the past 90 days
• 18 years or older
• Own at least one firearm located in your home or vehicle
• Are able to speak and understand the English language
• Have an Apple or Android smartphone 

Age Range

18 - 99 years

Official Title

Identification of novel immunogenic proteins from Bordetella pertussis

Purpose

The purpose of this study is to identify new targets to include in a next generation for pertussis (whooping cough). Our goal is to identify new antigens that generate better immune responses against Bordetella pertussis.

You will be in the study for one day when you provide the blood sample.

 

Could this study be right for you?

• 25-40 years old and do not have diabetes, heart disease, hypertension, auto-immune disease
• Not taking any steroid medications
• Not pregnant
• Know your immunization history
• One time visit
• Healthy Volunteer

Age Range

25 - 40 years

Official Title

Short-term and long-term impact of COVID-19 on multiple sensory systems

Purpose

The purpose of this study is to assess the short-term and long-term impact of COVID-19 on multiple sensory systems, including smell, taste, hearing, and balance.

The study requires about 2.5 hours of your time for your first visit, during which you may undergo smell, taste, hearing, motion, and balance tests. You may be require to participate several follow-up visits, each last 1.5 hours, if you continue to experience symptoms.

 

Could this study be right for you?

• Adults diagnosed with COVID 19 within the past 1-8 weeks
• Adults with previous COVID-19 diagnosis and has persistent (>90 days) complaints of sensory dysfunctions (smell, taste, chemesthesis, hearing, balance, dizziness)
• Adult with a recent (<8 weeks) upper respiratory infection (cold, flu, etc.)
• Adult with a previous upper respiratory infection (cold, flu, etc.) and has complaints of sensory dysfunctions (smell, taste, hearing, balance, dizziness)

Age Range

18 - 99 years

Official Title

E-cigarette Nicotine Concentration and Forms: Differential Appeal to Smokers versus Non-smokers

Purpose

This study will examine the effect of different e-cigarettes on product appeal.

Could this study be right for you?

• A current e-cigarette user
• 21-24 years old
• Willing to attend a study visit

OR

• A current smoker
• 25-50 years old
• Willing to attend a study visit
• Willing to try e-cigarettes

Age Range

21 - 50 years

Official Title

Decoding Social Perceptions in Naturalistic Contexts

Purpose

The purpose of this study is to examine impressions on foods. This study involves looking at brain activity while you perform simple tasks (judging images of different foods). 

The duration of this study will last 3 hours. 

Could this study be right for you?

• Free of MRI contradictions
• No dietary destrictions
• Normal vison
• Right handed

Age Range

18 - 35 years

Official Title

Agreement within Romantic Relationships

Purpose

The purpose of this study is to assess the agreements within romantic relationships on a variety of topics including politics, psychology and the nature of relationships.

Could this study be right for you?

• Must have been in a heterosexual relationship for 3 months

Age Range

18 - 60 years