A Study about Retirement from Contact Sports after Concussion
The purpose of this study is to learn about the experiences of children and young adults after they stop playing contact sports due to concussion.
- Male and females aged 14-22 years old
- Retired from contact sports due to prior concussion
Additionally, a parent may participate if their child enrolls.
A Study about Brain Imaging on Forming Impressions of Food
The purpose of this study is to examine impressions on foods. This study involves looking at brain activity while you perform simple tasks (judging images of different foods).
The duration of this study will last 3 hours.
- Free of MRI contradictions
- No dietary destrictions
- Normal vison
- Right handed
Buckeye Concussion Knowledge Survey (BUCKS)
The purpose of this study is to examine health outcomes in former Ohio State University athletes who played a varsity sport during their time at OSU. The objective is to determine whether athletes who sustained a concussion have different health outcomes than those who did not sustain a concussion. Any former OSU varsity athlete can participate in a 20-minute online survey.
- Anyone who has played a varsity sport as an undergraduate student at OSU, and they have now graduated (i.e., OSU athlete alumni). There are no other restrictions in terms of age, sex/gender, type of sport, etc.
A Study about Retirement from Contact Sports after Concussion
The purpose of this study is to understand the experiences of children and young adults after medical retirement from contact sports due to concussion(s).
Participants and their parent(s) will complete online questionnaires (about 10 minutes) at the time of enrollment. You will then be scheduled for an interview (about 30 minutes) by video meeting or phone.
- Children and young adults who have retired from contact sports or other high-risk activities (i.e. dirt bike riding, downhill skiing...) due to prior concussion.
- Parents may participate if their child enrolls.
Blood Pressure Health for Black/African American Women Caregivers
The purpose of this study is to determine the feasibility of a group delivered intervention for stress and blood pressure in African American women caregivers.
- Diagnosis of HTN treated with an antihypertensive medication or risk of HTN that includes obesity and high cholesterol
- Age 40 and older
- A caregiver rating of the PLWD of 2 or greater on the Alzheimer’s Dementia-8 scale
- Caregiver provides unpaid care to a PLWD at least 10 hours per week or assists with at least one instrumental activity of daily living
- Self-identifies as Black/African American
- English speaking
- Access to a telecommunications device such as the internet via desktop, laptop/tablet, smartphone, or telephone
A Study about Eye Teaming, Focusing Ability and Quality of Life
The purpose of this study is to assist in development of a new quality of life survey that can be used to learn more about how eye teaming, focusing ability and eye movement problems affect a child’s life.
- Children experiencing eye teaming, focusing, and eye movement problems (with recent concussion or non-concussed)
- Children with amblyopia (lazy eye) are excluded
A Study About the Development of Learning in African-American/Black Children
The purpose of this study is to investigate the early development of attention, learning, and memory during childhood. Participation in this study includes 4, 90-minute-long visits to the lab per year. During these visits, your child will play 2-3 fun, computerized games. These games are designed to assess various aspects of their cognitive ability.
The duration of the study will last 4 years.
Eligibility Criteria:
- African-American/Black children who are 4 years old
A Study About Gene Therapy for Early Alzheimer’s Disease (AD) and Mild Cognitive Impairment (MCI)
The primary aim of this study is to determine whether administration of the nervous system growth factor "Brain-Deruved Neurotrophic Factor" (BDNF) to eligible patients with Alzheimer's disease and Mild Cognitive Impairment is safe and tolerable. This study will be used to determine whether BDNF administration reduces neuronal loss and rebuilds synapses in the brain of patients with Alzheimer's Disease (AD) and Mild Cognitive Impairment (MCI).
- Male and Females aged 50 years or older
- Diagnosis of dementia due to Alzheimer's Disease/Diagnosis of Mild Cognitive Impairment (MCI) due to Alzheimer’s Disease
- A caregiver is available who has frequent contact with the subject, agrees to observe for adverse events, and will accompany the subject to all clinic visits for the duration of the protocol
- CT or MRI scans within 24 months prior to screening without evidence of an infection, infarction, or other focal
Inclusion Criteria varies, please contact Study Coordinator for more information.
The below Exclusion Criteria apply to both the AD and MCI groups.
- Any significant neurological disease other than suspected incipient disease
- History of schizophrenia
- History of systemic cancer within the past 18 months (non-metastatic skin cancers are acceptable).
- Any significant systemic illness or unstable medical conditions which could lead to difficulty complying with the protocol
- Use of any investigational drugs within thirty days or five half-lives, whichever is longer, prior to screening.
Exclusion Criteria varies, please contact Study Coordinator for more information.
Sleep and Blood Sugar in People with Alzheimer's Disease
The purpose of this study is to learn about sleep and blood sugar (glucose) levels in people living with Alzheimer’s disease (AD). Another purpose of the study is to see how people with AD and their caregivers/family members feel about wearing small devices to measure sleep and blood sugar.
The duration of this study is 10 days.
- 60 years or older, with Alzheimer’s disease,
- Has a caregiver 18 years or older,
- Willing to wear a watch-like device,
- Willing to wear a small sensor on the skin
An Observational Study to Examine School Transition after Traumatic Brain Injury
The purpose of this study is to understand the best ways to help students return to school after brain injury of any severity. This is important to study because finding the best ways to help students go back to school right after brain injury, and over time, can help improve student success and recovery.
Your participation in the study would take place when you/your child begins the study and then at 3 months, 6 months, 12 months, 2 years (if applicable) and 3 years (if applicable) after the study starts.
• Students aged 5 to 18 years old
• In kindergarten through 12th grade
• Must Speak English
• Traumatic Brain Injury (TBI) of any severity
• Parent/caregiver is willing to share medical and academic information with the research team (all study activities are virtual/remote)