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A Study to Examine if a Foot Stool can Make it Easier for People with Constipation to have a Bowel Movement (FASED Study)
Official Title FASED (Footstool in Alleviating Symptoms of Evacuation Disorder)Purpose
The purpose of this research study is to see if using a footstool can make it easier to have bowel movements in patients who suffer from chronic constipation. The participants will be given a free footstool to use. They will be asked to keep a record of their bowel symptoms and answer some surveys about their symptoms on a phone or computer.
You will be in the study for approximately 12 weeks. This includes 2 weeks before you start using the footstool, followed by 8 weeks where you will be using the footstool and up to 2 weeks to complete your initial and final surveys.
Could this study be right for you?
- At least 18 years old
- Able to understand English
- Symptoms such as feeling incompletely empty after a bowel movement, needing to strain a lot when having a bowel movement or needing to use maneuvers such as rocking one's body back and forth or using their finger to remove stool.
Age Range
18 - 99 -
A Study to Examine Sex Differences in Pain Reports and Brain Activation in Older Adults with Alzheimer's Disease
Official Title Sex Differences in Pain Reports and Brain Activation in Older Adults with Alzheimer's DiseasePurpose
The purpose of this study is to examine how men and women with and without dementia might perceive and respond to pain or discomfort.
Participants may complete various questionnaires by phone or video conferencing once a week for up to 8 weeks with an optional MRI screening.
Could this study be right for you?
- Men and women aged 60 years or older
- Dementia or memory issues
Participants and their caregiver (if applicable) may complete only 1 day of the study, or they may complete as many as they would like for up to 8 days total.
Age Range
60 and up -
A study on language impairment following a stroke
Official Title Laying the Groundwork for Personalized Medicine in Aphasia Therapy: Genetic and Cognitive Predictors of Restorative Treatment ResponsePurpose
This NIH-funded project will investigate patient-specific factors that may influence response to therapy for language impairment after stroke, or aphasia. Results from this work will assist with better estimation of prognosis for stroke survivors with aphasia, which could empower patients and families to make more informed health care decisions about how to pursue the most appropriate rehabilitation services based on their unique characteristics, such as genetics, cognitive skills, and brain structure after stroke.
Could this study be right for you?
Participants must meet the following criteria:
- Native English speaker
- Able to have an MRI
Age Range
18 and up -
Studying the Effects Nitrous Oxide (Laughing Gas) Has on Aggression
Official Title Nitrous Oxide and Cortico-Limbic Function in Aggression (Laughing Gas Study or LGS).Purpose
The purpose of this study is to see how laughing gas (nitrous oxide) changes brain activity in study participants with and without “anger issues”. Brain activity is measured by Magnetic Resonance Imaging.
The length of time you will be involved in this study will be 4-8 weeks.
Could this study be right for you?
- You are a medically healthy man or woman
- You are between the ages of 21 and 55 years of age
- Do not abuse alcohol or other drugs
- With a current history of “anger issues”
- Able to complete study sessions during the week
Age Range
21 and up -
Transitioning From Booster Seats to Seat Belts
Official Title Booster Seats InterviewPurpose
To explore how parents make the decision on transitioning their children from booster seats to seat belts; what factors may influence parents’ decision on the transition.
Could this study be right for you?
Inclusion criteria:
- At least 18 years of age
- A parent or legal guardian who is responsible for transporting their child routinely
- Have a child who stopped using booster seats within 1 year prior to the interview date, and the child who made the transition must be the first child of the parent
- Drive with a child at least once per week
- In good general health
- Fluent in English
Age Range
20 and up -
A Study Comparing Upadacitinib to Dupilumab in Adult Subjects with Moderate to Severe Atopic Dermatitis
Official Title M16-046: A Phase 3b Multicenter, Randomized, Double-Blind, Double-Dummy, Active Controlled Study Comparing the Safety and Efficacy of Upadacitinib to Dupilumab in Adult Subjects with Moderate to Severe Atopic DermatitisPurpose
The purpose of this study is to compare the effectiveness and safety of upadacitinib (ABT-494) versus dupilumab for the treatment of adult subjects (18-75 years of age) with moderate to severe atopic dermatitis (AD) who are candidates for systemic therapy.
Could this study be right for you?
- Subject must have chronic Atopic Dermatitis (AD) with onset at least 3 years prior to study participation
- Subject must have > or = 10% body surface area involvement of atopic dermatitis
- Subject must have had inadequate response to topical corticosteroids or topical calcineurin inhibitors within the past 6 months
- OR documented systemic treatment for AD within the past 6 months
- OR for whom topical treatments are otherwise medically inadvisable
- No prior exposure to any JAK inhibitor (e.g., ruxolitinib, tofacitinib, baricitinib, upadacitinib, PF-04965842, and filgotinib)
- No prior exposure to dupilumab
Age Range
18 and up -
A Study for Night Shift Workers
Official Title Transcranial Direct Current Stimulation Therapy for Sleepiness Related to Shift Work Disorder (tDCS-SWORD)Purpose
This research study aims to determine the effects of a noninvasive form of brain stimulation on alertness for night shift workers.
Could this study be right for you?
- You are age 18 to 65
- You are currently working the night shift at least 3x/week
- You are suffering from sleepiness at work
- You do not have significant heart and lung problems
- You work within the Columbus, OH area
Age Range
18 and up -
Decision Making Among Couples Concerning "Permanent/Irreversible" Birth Control
Official Title Couple Dynamics Surrounding Contraceptive SterilizationPurpose
This study aims to understand people’s experiences with contraceptive sterilization (such as tubal ligations or vasectomies).
The purpose of this study is to better understand how adults decide to use sterilization as
their main form of birth control. By examining sterilization decisions, this study will
provide a better understanding of how individuals describe and explain their decision
making process.In this study we are interested in learning how people discuss these decisions with their partner, as
well as everyday interactions with their partner, other forms of birth control, and attitudes
about gender more generally.Could this study be right for you?
- Ages 21-55
- Have used tubal ligation or vasectomy as primary contraception, WITHIN the last five (5) years
Participants will be asked to answer a series of questions regarding their experience with sterilization. Interviews will be digitally recorded by audiotape and will remain confidential. The duration of the interview will last approximately one hour to one hour and thirty minutes.
Age Range
21 and up -
Physical Therapy Study for Young Children (6 months to 24 months) with Motor Delays
Official Title Daily and Weekly Rehabilitation Delivery for Young Children with Cerebral Palsy ("DRIVE")Purpose
The purpose of this study is to find out how to best distribute physical therapy sessions for your children with significant motor delays.
Participants will receive 40 hours of physical therapy. Participants will be randomly assigned to one of the three treatment groups: intensive, moderate or weekly.
Could this study be right for you?
- Children ages 6 months to 24 months of age
- Has a diagnosis of cerebral palsy or an acquired brain injury prior to age of 24 months.
- Has persistent delays in motor skills
- Ability to participate in outpatient physical therapy and attend visits consistently
The intensive group will receive physical therapy 2 hours per day, 5 days per week for 4 weeks followed by a 16 week break from outpatient physical therapy. The intermediate group will receive physical therapy 2 hours per day, 3 days per week for 6.6 weeks followed by a 13 week break from outpatient physical therapy. The weekly group will receive physical therapy for 2 hours per day, 1 day per week for 20 weeks.
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Media Use and Youth--For Those 12-17 Years of Age
Official Title Media Use and Youth--For Those 12-17 Years of AgePurpose
Researchers want to learn how teens use technology like TV, the internet, video games, and music. The study examines children’s use of media on a daily basis over two weeks.
Your child and one parent will meet with researchers two times on campus. Your child will answer some questions during those meetings. The first meeting will be for about 2 hours and the second meeting will be for about 30 minutes. Over a two week period between those meetings, the child will report daily on activities using a tablet supplied by the study.
Could this study be right for you?
- Ages 12-17 accompanied by one parent or guardian
Age Range
12 and up