Contact Lens Study

Official Title
Clinical Evaluation of Comfilcon A Contact Lenses
Purpose

The objective of this study is to confirm the clinical performance of two different lots of Biofinity contact lenses.  With different manufacturing lines making comfilcon A product, this study seeks to confirm the performance of Biofinity over one month of wear.

Could this study be right for you?

Inclusion:

  • Have had a self-reported oculo-visual examination in the last year.  
  • Are at least 18 years of age and has full legal capacity to give their informed consent.
  • Have read and understood the informed consent letter. 
  • Are willing and able to follow instructions and maintain the appointment schedule.
  • Have a contact lens spherical prescription between -0.50 D to -6.00 D (inclusive)
  • Are correctable to a visual acuity of 20/40 or better (in each eye) with their habitual vision correction or 20/20 best-corrected.
  • Have spectacle cylinder of ≤ 0.75 D in both eyes.
  • Is a habitual Biofinity (comfilcon A) wearer and worn a comfilcon A (Biofinity) lens for at least one month (minimum of 8 hours a day, 5 days per week)
  • Currently employ the use of a peroxide or multipurpose solution cleaning and disinfecting regimen in one of the following brand names:
    • Bausch and Lomb BioTrue Multi-Purpose Solution
    • Bausch and Lomb BioTrue Hydration Plus Multi-Purpose Solution
    • Bausch and Lomb ReNu Advanced Formulation Multi-Purpose Solution
    • Alcon Opti-Free Puremoist with Hydraglyde Multi-Purpose Solution
    • Alcon Opti-Free Replenish Multi-Purpose Solution
    • Alcon Clear Care Plus Hydrogen Peroxide Solution
    • Acuvue RevitaLens Multi-Purpose Solution
  • Have clear corneas and no active ocular disease.
  • Have not worn habitual lenses for at least 12 hours before the baseline/screening examination
  • Are willing to wear the study contact lenses for at least 8 hours per day, 5 days per week

Exclusion

  • Have never worn contact lenses before.
  • Are currently wearing daily disposable contact lenses.
  • Have any systemic disease affecting ocular health.
  • Are using any systemic or topical medications that will affect ocular health.
  • Have any ocular pathology or abnormality that would affect the wearing of contact lenses.
  • Have any clinically significant lid or conjunctival abnormalities, active neovascularization or any central corneal scars.
  • Are aphakic.
  • Have undergone corneal refractive surgery.
  • Are participating in any other type of eye related clinical or research study.
  • Require a change in lens power from more than 1 diopter as dictated by over-refraction with their habitual lens prescription.
Age Range
18 years and up

Research Study on Light Sensitivity after Head Injury

Official Title
Effect of Fixation Training with Colored Light Targets on Traumatic Brain Injury-Associated Photophobia
Purpose

Researchers at The Ohio State University College of Optometry are seeking individuals with a recent history of head trauma who are experiencing light sensitivity. The goal of this study is to determine if daily 20 minute fixation training sessions using a colored (red or blue) light target affects symptoms of light sensitivity, or alters other measurements of the eyes and vision including pupil response.  

This study will involve attending five 1-2 hour study visits, occurring every 1.5 months for 6 months. Study visits will include answering questions about eye and health history, completing surveys, reading letters on an eye chart, having the pupils measured in response to flashes of light, measuring the side vision, measuring eye alignment and in some cases focusing ability. Outside of the study visits, participants will also complete daily 20 minute fixation training sessions for 6 months using a colored (red or blue) light target, completed at home between study visits.

Could this study be right for you?
  • Must be 18 to 80 years old
  • Experienced a head injury 3 or more months ago
  • Current symptoms of light sensitivity
  • Be healthy and have good eye health 
Age Range
18 - 80 years

Contact Lens Study in Adults with Presbyopia

Official Title
Evaluation of Wear Experience with Dailies TOTAL1 Multifocal® Contact lenses in Presbyopic Adults That Have Dropped out of Contact Lens Wear
Purpose

The purpose of this study is to learn about the wear experience of adults who dropped out of contact lens wear once they became presbyopic. 

Could this study be right for you?
  • Adults who have dropped out of contact lens wear 
  • Ability to attend 3 visits over the course of 5 weeks
  • Satisfy all other study eligibility and exclusion criteria
Age Range
38 years and up

A Study about a FDA Approved Contact Lenses for Management of Myopia

Official Title
MiSight® 1 Day Post-Approval Study for Effectiveness and Visual Symptoms
Purpose

The purpose of this study is to evaluate if FDA approved contact lenses can reduce the progression of nearsightedness in children. Children who participate in this 4-year study will be asked to wear the study provided contact lenses at least 6 days a week and be willing to attend visits at The OSU College of Optometry one month after starting treatment and every six months thereafter. Visits will include a comprehensive eye exam and contact lens fitting at no cost.

Could this study be right for you?
  1. Children ages 8 to 12 years old.
  2. No previous medication or contact lenses related to myopia control.
  3. Glasses and/or contact lens prescription between -0.75 and -4.00 diopters.
  4. Satisfy all other study eligibility criteria.
Age Range
8 - 12 years

Determining the Best Glasses Prescription for Children with Down Syndrome

Official Title
Dilated Wavefront versus Non-Dilated Wavefront for Metric-Optimized Refraction Procedure for Individuals with Down Syndrome
Purpose

The purpose of this study is to examine whether we can use an instrument that measures how the eye focuses light to determine the best glasses prescription.

Could this study be right for you?
  • Children with Down syndrome age 5 to 17 years
  • Able to do vision tests by naming or matching shapes or letters
  • Able to look at lights for short periods of time
  • No nystagmus (uncontrolled eye movements when trying to look at things)
  • Safe to dilate the eyes - we will screen medical history, eye health, and allergies to determine this
  • No scars on the front of the eye
  • No cataracts
  • No eye diseases like glaucoma or retinal problems
Age Range
5 - 17 years

Evaluation of Hand/Eye Coordination with Multifocal Contact Lenses Compared to Progressive Addition Spectacles

Official Title
Hand and Eye coordination with Presbyopic vision correction
Purpose

This study is looking to compare the use of multifocal contact lenses to progressive-addition (no-line bifocal) glasses. Participants will be asked to perform a hand/eye coordination task once while wearing glasses, and once while wearing contact lenses.

The duration of the study lasts 1 hour. 

Could this study be right for you?
  • Must currently have presbyopia (unable to focus on objects at near).
  • Must have up-to-date pair of progressive-addition glasses (addition power of +1.50 D or higher), worn for at least 2 weeks prior to screening visit.
  • Must be a wearer of multifocal contact lenses.
  • Meet other study eligibility criteria.

A Study about Eye Teaming, Focusing Ability and Quality of Life

Official Title
Development of Patient-Reported Outcome Measures for Children with Concussion-Related and Non-Concussion-Related Non-Strabismic Binocular Vision, Accommodative and Visual Tracking Problems: Phase 1
Purpose

The purpose of this study is to assist in development of a new quality of life survey that can be used to learn more about how eye teaming, focusing ability and eye movement problems affect a child’s life.

Could this study be right for you?
  • Children experiencing eye teaming, focusing, and eye movement problems (with recent concussion or non-concussed)
  • Children with amblyopia (lazy eye) are excluded
Age Range
8 - 17 years

A Randomized Trial to Evaluate Sequential vs Simultaneous Spectacles plus Patching for Amblyopia in Children 3 to <13 Years Old

Official Title
AMBLYOPIA TREATMENT STUDY (ATS22): A Randomized Trial to Evaluate Sequential vs Simultaneous Spectacles plus Patching for Amblyopia in Children 3 to <13 Years Old
Purpose

The purpose of this study is to evaluate if treating amblyopia (lazy eye) with glasses and patching at the same time improves vision as well as treating amblyopia first with glasses and then with patching, if needed.

Could this study be right for you?
  • Visual acuity in the amblyopic eye between 20/40 and 20/200
  • No previous treatment for amblyopia, including glasses or contact lenses
  • Amblyopia (lazy eye) in one eye
Age Range
3 - 12

Tear Film in Children Study

Official Title
Tear Film and Corneal Profile of Pediatric Contact Lens Wearers
Purpose

The goal of this study is to describe the risks associated with overnight orthokeratology contact lens wear in children by identifying corneal and tear film changes. The study aims to describe and compare the tear film components in a pediatric sample wearing orthokeratology contact lenses (used to change the shape of the cornea), soft contact lenses, or glasses. Additionally, the study aims to compare the corneal thickness profile in a pediatric sample wearing orthokeratology contact lenses, soft contact lenses, or glasses. 

This study requires one visit only. The overall timeline from subject recruitment to study completion is dependent upon subject and examiner availability and scheduling. As long as no changes occur to subject eligibility between initial recruitment and the study visit, there is some flexibility with timing.

 

Could this study be right for you?
  • Near-sighted prescription between -1.00D and -6.00D
  • Current correction with glasses, soft contact lenses, or overnight orthokeratology contact lenses
  • Has been wearing current correction for 6 months or longer
  • Good eye and overall health
Age Range
7 - 17

A Study About the Development of Learning in African-American/Black Children

Official Title
Ontogenesis of Categorization; Linking development, mechanisms, and biology
Purpose

The purpose of this study is to investigate the early development of attention, learning, and memory during childhood. Participation in this study includes 4, 90-minute-long visits to the lab per year. During these visits, your child will play 2-3 fun, computerized games. These games are designed to assess various aspects of their cognitive ability. 

The duration of the study will last 4 years.

Could this study be right for you?

Eligibility Criteria: 

  • African-American/Black children who are 4 years old 
Age Range
4 - 4