Research studies are looking for volunteers just like you. Both healthy volunteers and participants with specific health conditions are needed to help answer important questions impacting the health of our friends and family. Join us to improve the health of others.
Study Categories
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PREVENTABLE
Official Title PRagmatic EValuation of evENTs And Benefits of Lipid-lowering in oldEr adultsPurpose
The purpose of PREVENTABLE is to learn if taking a statin could help older adults live well for longer by preventing dementia, disability, or heart disease. The duration of the study will last 5 years.
Could this study be right for you?
Inclusion Criteria:
- Community-dwelling adults
- Age ≥75 years
- English or Spanish as primary language
Exclusion Criteria:
- Clinically evident cardiovascular disease defined as prior myocardial Infarction (MI), prior stroke, prior revascularization procedure, or a secondary prevention indication for a statin (clinician determined)
- Hospitalization for a primary diagnosis of heart failure in the prior 12 months (Note: History of heart failure in the absence of recent hospitalization or clinically evident cardiovascular disease is not an exclusion)
- Dementia (clinically evident or previously diagnosed)
- Dependence in any Katz Basic Activities of Daily Living [ADL] (with the exception of urinary or bowel continence)
- Severe hearing impairment (preventing phone follow up)
- Unable to talk (preventing phone follow up)
Exclusion Criteria varies, please contact Study Coordinator for more information.
Age Range
75 years and up -
Breathing Training Program for Breast Cancer Survivors with Obesity
Official Title Reducing exercise intolerance through inspiratory muscle training in obese breast cancer survivors (IMOCS)Purpose
The purpose of this study is to better understand why some survivors of breast cancer have difficulty exercising. We also want to learn if breathing exercises can make it easier to tolerate exercise.
Could this study be right for you?
- Breast Cancer Survivor
- Completed treatment within 6 months–5 years
- Have obesity, defined as body mass index between 30-50 kg/m2
- Can exercise independently
Age Range
18 years and up -
The Tree of Hope: A Method to Reduce Burnout, Improved Hope and Increase Resilience
Official Title The Tree of Hope: A Method to Reduce Burnout, Improved Hope and Increase ResiliencePurpose
The purpose of this study is to improve the sense of hope and build resilience through creating one’s Tree of Hope. This study is being done because we see that today’s environment is quite stressful and this can lead to people feeling less hopeful in their present and the future.
Could this study be right for you?
- At least 18 years old
- Able to read and understand English
- Healthy people and patients will be eligible for this research study
- Participants will be eligible even if they are not seen at OSU for their care.
- We will not abstract any data from electronic health records. Patients will complete a survey that asks them questions about their health conditions
Exclusion Criteria
- Any physical or mental condition that the principal investigator considers as impacting the ability of the patient to participate in the research study. Examples include visual or hearing impairment, arthritis, weakness or other medical problem that impairs their ability to write.
Age Range
18 years and up -
A Study to Evaluate Baricitinib in Adult Patients with Severe or Very Severe Alopecia Areata
Official Title A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Operationally Seamless, Adaptive Phase 2/3 Study to Evaluate the Efficacy and Safety of Baricitinib in Adult Patients with Severe or Very Severe Alopecia Areata BRAVE-AA1Purpose
The purpose of this study is to evaluate the efficacy of baricitinib.
Could this study be right for you?
- Subject must self-identify as Black or African American
- Subject's current episode of alopecia areata must be more than 6 months and no longer than 8 years
- Subject must not have any spontaneous improvement
- Subject must be in good general health with no history of tuberculosis, heart disease, cancer, HIV, hepatitis B or C, or blood clots
- Female subjects must not be pregnant, breastfeeding, or considering becoming pregnant for the duration of the study
Age Range
18 years and up -
A Study to Evaluate Rocatinlimab in Adults with Atopic Dermatitis (Ezcema)
Official Title A Phase 3, Randomized, 24-week, Placebo-controlled, Double-blind Study to Assess the Efficacy, Safety and Tolerability of Rocatinlimab (AMG 451) Monotherapy in Adult
Subjects With Moderate-to-severe Atopic Dermatitis (AD) (ROCKET-Horizon)Purpose
The purpose of this study is to evaluate the efficacy of rocatinlimab.
Could this study be right for you?
- Subject must have a diagnosis of atopic dermatitis for a least 6 months prior to study visit
- Subject must have tried a topical medication with little to no improvement
- Subject must be in good general health with no history of tuberculosis, heart disease, cancer, HIV, hepatitis B or C, or blood clots
- Female subjects must not be pregnant, breastfeeding, or considering becoming pregnant for the duration of the study
Age Range
18 years and up -
A Study to Evaluate Povorcitinib in Adults with Hidradenitis Suppurativa (HS)
Official Title A Phase 3, Double-Blind, Randomized, Placebo-Controlled, Efficacy and Safety Study of Povorcitinib (INCB054707) in Participants With Moderate to Severe Hidradenitis Suppurativa
Purpose
The purpose of this study is to evaluate the efficacy of povorcitinib.
Could this study be right for you?
- Subject must have a diagnosis of hidradenitis suppurativa for at least 3 months prior to study visit
- Subject must have at least 5 active HS spots in 2 different body areas
- Subject must have tried an oral or injected medication for HS with little to no improvement
- Subject must be in good general health with no history of tuberculosis, heart disease, cancer, HIV, hepatitis B or C, or blood clots
- Female subjects must not be pregnant, breastfeeding, or considering becoming pregnant for the duration of the study
Age Range
18 years and up -
Impact of A Low Glycemic Index Diet on Blood Pressure and Blood Sugar in Individuals with Spinal Cord Injury
Official Title Two Birds with One Stone: Impact of A Low Glycemic Index Diet on Postprandial Hypotension and Glucose Metabolism in Individuals with Spinal Cord Injury (FIP)Purpose
The purpose of this study is to examine the effect of a short-term low glycemic index diet on blood pressure and blood sugar control after eating.
Could this study be right for you?
- Adults aged 18-65 years old
- Chronic spinal cord injury
- Level of injury between C4 and L2
Age Range
18 - 65 years -
Brains, Emotion Regulation and Adolescent Moods (BEAM) Study
Official Title Neurodevelopmental Mechanisms Underlying the Onset of Depression among At-Risk Youth: The Role of Dysregulation in the Negative Valence SystemPurpose
The purpose of this study is to test whether changes in the way in which we react and respond to emotional or stressful information represent a risk factor for depression in kids of mothers with and without depression. Findings from the study have the potential to decrease the high rates of depression observed in children of depressed mothers.
Could this study be right for you?
You may be eligible for this study if:
- You are 18-65 years old and female.
- You have a biological child who is between 9 and 14 years of age.
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Understanding Patient Experiences of Gestational Diabetes
Official Title A Multi-Actor Examination of Gestational Diabetes Mellitus (GDM)Purpose
This study aims to examine the experience of people who have been diagnosed or are currently living with gestational diabetes, including how they manage and make sense of their diagnosis.
Could this study be right for you?
- Aged 18 years or older
- Must live in the state of Ohio
- Must be currently pregnant and have been diagnosed with gestational diabetes OR must have been diagnosed with gestational diabetes during a recent pregnancy (within the last 12 months)
Age Range
18 years and up -
A Study for Active Military Service Members (or recently served); Examining Uncertainty, Health, and Home Safety Practices
Official Title Uncertainty and Firearms: Obtaining Secure Storage (UFOS)Purpose
The purpose of this study is to examine whether fear of uncertainty plays a role in home safety practices among firearm owners who are currently or have recently served in the U.S. military.
Could this study be right for you?
- Currently serving in any Branch or Component of the U.S. military, or were discharged from the U.S. military within the past 90 days
- 18 years or older
- Own at least one firearm located in your home or vehicle
- Are able to speak and understand the English language
- Have an Apple or Android smartphone
Age Range
18 - 99 years -
Research Study on Aging and Health after Cancer
Official Title E-PROOF: E-intervention for Protein Intake and Resistance Training to Optimize FunctionPurpose
Our team is looking to improve the health of older cancer survivors after they have completed cancer treatment. Specifically, this 12-week study looks to improve older cancer survivors' physical function and related health outcomes (muscle strength, dietary quality, health-related quality of life, self-efficacy, weight management).
Could this study be right for you?
-History of stage I-III breast, colorectal, and prostate cancer
-Completion of curative treatment (chemotherapy, radiation, surgery)
-Have an email address
Age Range
65 years and up -
Assessing Non-invasive Spinal Stimulation to Evaluate its Safety and Effectiveness in Individuals with Spinal Cord Injury
Official Title ExaStim Upper Limb Pivotal Clinical Validation StudyPurpose
The purpose of this study is to evaluate the safety and effectiveness of ExaStim® transcutaneous spinal stimulation on upper extremity function when applied in combination with physical therapy (PT) and/or occupational therapy (OT).
Participants will be randomized to the stimulation group or a control group. Outcomes will include sensory, motor, and functional tests, as well as questionnaires.
Could this study be right for you?
- Aged 22 years or older
- Traumatic chronic spinal cord injury
- Level of injury between C2-T2
- No active implanted medical device for electrical stimulation
- No Botox for 3 months
- Have a chronic, traumatic SCI (chronic is >12 months since injury, or 6 months if unchanged symptoms)
- Has some, but limited upper extremity function
- BMI <40
- Cannot be pregnant
Age Range
22 years and up