Search Studies

Official Title A Multicentre, Randomised, Double-blind, Parallel-group, Placebo-controlled, 24-week Phase 3 Study with an Open-label Extension to Evaluate the Efficacy and Safety of Benralizumab in Patients with Hypereosinophilic Syndrome (HES)

Purpose

The purpose of this study is to see if benralizumab (biologic drug), given as injections under the skin, can help control your Hypereosinophilic Syndrome (HES) better if it is added to available standard of care HES medications which you may be currently taking. 

HES (Hypereosinophilic Syndrome) is a disease characterized by high levels of eosinophils (a particular type of white blood cell) in your blood and a build-up of eosinophils in some organs and tissues (like skin, heart, lungs, intestines or others) causing their dysfunction.

The duration of the study will last 18 months.

Could this study be right for you?

 

• Eosinophil (a type of white blood cells) count ≥ 1000 cells/μL at screening
• Documented diagnosis of Hypereosinophilic Syndrome (HES)
• History of persistent eosinophilia >1500 cells/μL (at least 2 examinations, interval ≥1 month)
• End organ manifestations attributable to the eosinophilia

Inclusion and Exclusion Criteria varies, please contact Study Coordinator for more information.

Age Range

18 years and up

Official Title Retirement from contact sports after concussion

Purpose

The purpose of this study is to learn about the experiences of children and young adults after they stop playing contact sports due to concussion.

Could this study be right for you?

• Male and females aged 14-22 years old
• Retired from contact sports due to prior concussion

Additionally, a parent may participate if their child enrolls. 

Age Range

14 - 22 years

Official Title Improving emergency care and outcomes of immune-related adverse events: The immune related emergency disposition index (irEDI)

Purpose

The purpose of this study is to learn more about how to best care for patients who have immune-related side effects and have received treatment with an immune checkpoint inhibitor. 

The duration of this study is 30 days. 

Could this study be right for you?

• Must speak English and/or Spanish
• Diagnosis of cancer (excluding non-melanoma skin cancer)
• Last immunotherapy received within 90 days of study enrollment

Age Range

18 years and up

Official Title BUckeye Concussion Knowledge Survey (BUCKS)

Purpose

The purpose of this study is to examine health outcomes in former Ohio State University athletes who played a varsity sport during their time at OSU. The objective is to determine whether athletes who sustained a concussion have different health outcomes than those who did not sustain a concussion. Any former OSU varsity athlete can participate in a 20-minute online survey.

Could this study be right for you?

• Anyone who has played a varsity sport as an undergraduate student at OSU, and they have now graduated (i.e., OSU athlete alumni). There are no other restrictions in terms of age, sex/gender, type of sport, etc.

Age Range

18 years and up

Official Title Retirement from Contact Sports after Concussion

Purpose

The purpose of this study is to understand the experiences of children and young adults after medical retirement from contact sports due to concussion(s).

Participants and their parent(s) will complete online questionnaires (about 10 minutes) at the time of enrollment. You will then be scheduled for an interview (about 30 minutes) by video meeting or phone.

Could this study be right for you?

• Children and young adults who have retired from contact sports or other high-risk activities (i.e. dirt bike riding, downhill skiing...) due to prior concussion.  
• Parents may participate if their child enrolls.

Age Range

14 - 22 years

Official Title The 5000 Baby Project

Purpose

The purpose of this study is to develop a screening tool to be used at birth to help lower the age at diagnosis of various developmental disorders. 

Your infant will lie on their back in their diaper and have a video recorded of their movements. You will be given a medical history questionnaire to fill out during the recording. The visit typically lasts 15-20 minutes.

Could this study be right for you?

• Any infants from birth - 6 months (corrected age if applicable) 
• Parent/legal guardian present and willing to provide informed consent
• Parent/Legal guardian is English Speaking

Official Title Safety, Tolerability, and Outcomes of Velpatasvir/SofosbuviR in Treatment of Chronic Hepatitis C Virus during Pregnancy (STORC), pregnant woman

Purpose

This study involves evaluating a medication for hepatitis C in pregnant women. 

If you are a pregnant woman with chronic hepatitis C and you join the study, you are consenting to enroll yourself and your baby after he/she is born.

Maternal participants will have 7 visits over approximately 7 months. Infant participants have four visits over approximately the first year of life.

Could this study be right for you?

(This is not a complete list)  

- Must be  18 - 45 years of age

- Chronic HCV infection of at least 6 months

- Singleton pregnancy at 20 + 0 to 30 + 0 weeks’ gestation

- Documented negative Hepatitis B testing for current infection (negative HBsAg test) prior to enrollment

- If living with HIV, must be on antiretroviral therapy

 

Exclusion Criteria (not a complete list)

- Plans to relocate away from the study site area in the next 16 months and unable/unwilling to return for study visits

- History of cirrhosis

- Known fetal chromosomal abnormality prior to enrollment

Age Range

18 - 45

Official Title Randomized Trial on Mobile Technology and Young Drivers' Cellphone Use

Purpose

The purpose of this study is to find out if a cell phone app affects driving behavior among young drivers. This information may help us develop public health and traffic safety strategies for young drivers.

 

 

Could this study be right for you?

• 18-24 years old at the time of recruitment
• Must have ownership and exclusive access to a car
• Must have car insurance with at least state-minimum coverage
• Must live in the Greater Columbus Metropolitan Area
• Must drive at least 2 days a week on average
• Must have functioning iPhone or Android smartphone with an active phone service account (Ex: Verizon, AT&T, etc.)
• Must not have a physical car insurance monitoring device or app installed
• Must speak and read English

Age Range

18 - 24

Official Title Leveraging DRVN driver training app to reduce risky driving intentions in novice teen drivers

Purpose

The purpose of this study is to see if the bonus safety messages and the amount of app use predicts safe driving attitudes and behaviors at licensure. We are recruiting Ohio teens with learner's permits to use a free driver training app called DRVN. 

Could this study be right for you?

• Must have learner's permit to drive in Ohio

Age Range

15 - 17

Official Title Linking Vestibular Function, Balance, and Falls

Purpose

The purpose of this study is to learn how information from different sensory systems, including the vestibular system (that portion of the inner ear which measures both motion and orientation of the head), are used by the brain to contribute to perceptions of tilt and motion, and balance control and posture. 

 

Could this study be right for you?

You may be eligible to participate in the study if you:

• Are male or female, 18 years of age through 39 years of age
• Have NO history of a balance or vestibular disorder

If you are eligible and enroll in the study, you will:

• Complete an on-line Health Screen Questionnaire
• Complete other on-line surveys/questionnaires depending on information provided in the Health Screen Questionnaire
• Complete vestibular and balance testing depending on information provided in the Health Screen Questionnaire, which will be performed in a vestibular research laboratory at a mutually convenient time

Age Range

18 - 39

Official Title Development of Patient-Reported Outcome Measures for Children with Concussion-Related and Non-Concussion-Related Non-Strabismic Binocular Vision, Accommodative and Visual Tracking Problems: Phase 1

Purpose

The purpose of this study is to assist in development of a new quality of life survey that can be used to learn more about how eye teaming, focusing ability and eye movement problems affect a child’s life.

Could this study be right for you?

• Children experiencing eye teaming, focusing, and eye movement problems (with recent concussion or non-concussed)
• Children with amblyopia (lazy eye) are excluded

Age Range

8 - 17 years

Official Title AMBLYOPIA TREATMENT STUDY (ATS22): A Randomized Trial to Evaluate Sequential vs Simultaneous Spectacles plus Patching for Amblyopia in Children 3 to <13 Years Old

Purpose

The purpose of this study is to evaluate if treating amblyopia (lazy eye) with glasses and patching at the same time improves vision as well as treating amblyopia first with glasses and then with patching, if needed.

Could this study be right for you?

• Visual acuity in the amblyopic eye between 20/40 and 20/200
• No previous treatment for amblyopia, including glasses or contact lenses
• Amblyopia (lazy eye) in one eye

Age Range

3 - 12