Pediatrics

Official Title

Development of Patient-Reported Outcome Measures for Children with Concussion-Related and Non-Concussion-Related Non-Strabismic Binocular Vision, Accommodative and Visual Tracking Problems: Phase 1

Purpose

The purpose of this study is to assist in development of a new quality of life survey that can be used to learn more about how eye teaming, focusing ability and eye movement problems affect a child’s life.

Could this study be right for you?

• Children experiencing eye teaming, focusing, and eye movement problems (with recent concussion or non-concussed)
• Children with amblyopia (lazy eye) are excluded

Age Range

8 - 17 years

Official Title

AMBLYOPIA TREATMENT STUDY (ATS22): A Randomized Trial to Evaluate Sequential vs Simultaneous Spectacles plus Patching for Amblyopia in Children 3 to <13 Years Old

Purpose

The purpose of this study is to evaluate if treating amblyopia (lazy eye) with glasses and patching at the same time improves vision as well as treating amblyopia first with glasses and then with patching, if needed.

Could this study be right for you?

• Visual acuity in the amblyopic eye between 20/40 and 20/200
• No previous treatment for amblyopia, including glasses or contact lenses
• Amblyopia (lazy eye) in one eye

Age Range

3 - 12

Official Title

Tear Film and Corneal Profile of Pediatric Contact Lens Wearers

Purpose

The goal of this study is to describe the risks associated with overnight orthokeratology contact lens wear in children by identifying corneal and tear film changes. The study aims to describe and compare the tear film components in a pediatric sample wearing orthokeratology contact lenses (used to change the shape of the cornea), soft contact lenses, or glasses. Additionally, the study aims to compare the corneal thickness profile in a pediatric sample wearing orthokeratology contact lenses, soft contact lenses, or glasses. 

This study requires one visit only. The overall timeline from subject recruitment to study completion is dependent upon subject and examiner availability and scheduling. As long as no changes occur to subject eligibility between initial recruitment and the study visit, there is some flexibility with timing.

 

Could this study be right for you?

• Near-sighted prescription between -1.00D and -6.00D
• Current correction with glasses, soft contact lenses, or overnight orthokeratology contact lenses
• Has been wearing current correction for 6 months or longer
• Good eye and overall health

Age Range

7 - 17

Official Title

An Intervention Study about Primary Care Algorithms for Early Identification of Young Women with von Willebrand Disease

Purpose

Researchers at Nationwide Children’s Hospital are seeking volunteers to be a part of a study looking at how to best screen for bleeding disorders in young women.

Participants will be asked to undergo a finger prick blood test and complete questionnaires. If their survey answers suggest they have heavy menses or abnormal bleeding, they will also be asked to have a blood draw on the same day.

Could this study be right for you?

• Are 9 to 21 years old
• Have had your first menstrual cycle

Age Range

9 - 21

Official Title

Mentoring to be Active: Peer Mentoring for Rural Appalachian Children to Reduce Overweight and Obesity

Purpose

The purpose of this study is to lower the rate of type 2 diabetes in rural Appalachia youth due to obesity and/or being overweight. Our long-term goal is to improve the health of underserved, high-risk youth.

This study will test the effectiveness of the Mentored Planning to be Active + Family on physical activity outcomes and health outcomes among rural Appalachian middle school aged youth suffering from either overweight or obesity.

We have local high school-aged teen mentors work closely with middle school youth to increase social support, self-efficacy, and self-regulation skills to sustain physical activity and improve health before the children enter high school.

The peer mentoring is followed by a 6-month family reinforcement program.

Some parents will provide child assessment data of perceived child physical activity behaviors and child health.

 

Could this study be right for you?

• Child has access to a computer or tablet device at home for virtual mentoring sessions/meetings
• Child suffers from overweight or obesity - does not need to be under the care of a health care professional for this condition
• Child and Parent able to participate read English at a 4th grade level. 
• Family not expected to move from rural Appalachia within the 18 months. 

Age Range

12 - 13

Official Title

A multi-year study of learning during childhood

Purpose

The purpose of this study is to investigate the early development of attention, learning, and memory.

The duration of the study will last over 4 years.

Participation in this study includes 4, 90-minute-long visits to the lab per year. During these 90-minute-long visits, your child will play 2-3 computerized games, designed to assess different aspects of their cognitive ability.

Could this study be right for you?

Children aged 4 years old only; children must be 4 years old at their initial visit to participate.

Age Range

4 and up

Official Title

STATBI: School Transitions after Traumatic Brain Injury

Purpose

The purpose of this study is to understand the best ways to help students return to school after brain injury of any severity. This is important to study because finding the best ways to help students go back to school right after brain injury, and over time, can help improve student success and recovery.

Your participation in the study would take place when you/your child begins the study and then at 3 months, 6 months, 12 months, 2 years (if applicable) and 3 years (if applicable) after the study starts.

Could this study be right for you?

• Students aged 5 to 18 years old
• In kindergarten through 12th grade
• Must Speak English
• Traumatic Brain Injury (TBI) of any severity
• Parent/caregiver is willing to share medical and academic information with the research team (all study activities are virtual/remote)

Age Range

5 and up

Official Title

Microdosed Atropine for the Reduction of Pediatric Myopia Progression (The CHAPERONE Study)

Purpose

The purpose of this study to test the safety and effectiveness of atropine 0.1% and atropine 0.01% eye solutions. These drugs are being tested to see if they slow the worsening of nearsightedness. Children who participate in this study will be asked to use their assigned study medication every night and willing to attend visits at The Ohio State University of Optometry 1 month after starting treatment. These visits will continue for 6 months until the duration of the study ends. This study will take place over a 4-year time period.

Could this study be right for you?

· Children aged 3 to < 13 years old. · No previous use of medications related to myopia control. · Glasses and/or contact lens prescription between -1.00 and -6.00 diopters. Interested guardians who believe their child may be eligible should contact study coordinators to further determine eligibility

Age Range

3 and up

Official Title

Measuring Sleep Problems in Children with Autism Spectrum Disorder (ASD)

Purpose

The purpose of this study is to get a better understanding and improve measurement of sleep problems in children with Autism Spectrum Disorder (ASD).

Total time involved in study will be approximately 5 hours

Could this study be right for you?

- Parents of children with ASD, and
- Children with ASD ages 3-12, with mild, medium or major sleep problems either currently or in the past
- Children on medication can participate if the medicine dose is stable for at least one month

Age Range

3 and up

Official Title

The Ontogenesis of Categorization (Children age 4)

Purpose

The purpose of the study is to investigate the early development of attention, learning and memory; this is a multi-year study.

All sessions will take approximately 60-120 minutes to complete. This study will be conducted in our lab, and mandated OSU COVID safety protocol will be followed.

Could this study be right for you?

- Children who are 4 years old
- Have normal or corrected to normal vision

Age Range

4 and up