Pediatrics

Official Title

Cognitive Development (Children 4-9 yrs old)

Purpose

The purpose of this study is to understand how children sort new information using simple memory exercises with animated computer games.

All sessions will take approximately 25-45 minutes to complete. Participating children will play memory games on our touchscreens and computers. For on-campus sessions, mandated OSU COVID safety precautions will be followed.

Could this study be right for you?

- Children ages 4-9 years old

Age Range

4 and up

Official Title

Perinatal Arterial Stroke: The I-ACQUIRE Study

Purpose

Children who suffered a stroke before or shortly after being born that was caused by blockage of blood flow in an artery, it often results in the child showing some weakness on one side of their body.

With this study, we want to find out if a type of therapy may help children who have weakness on one side of their body due to perinatal arterial ischemic stroke, learn how to better use their weaker arm.

All children will be in the study for about 13 - 15 months. Some children may be in the study for a longer period, depending on which treatment they receive during Phase 1 of the study. The I-ACQUIRE therapy involves fun learning and play, self-help activities, and manipulating interesting toys and objects.

Could this study be right for you?

- Your child must be between the ages of 8 and 36 months old when beginning this study
- Your child must have suffered an a perinatal arterial ischemic stroke
- Upper limb weakness
- Parents must be able to participate at least 1x/week for therapy and 40-60 minutes/day at home

Official Title

Characterizing Occupational Therapy Intervention for Children with Autism Spectrum Disorders

Purpose

We are actively recruiting typically developing children (ages 6 – 13 years) to participate in a new study looking at attention and sensory processing. In this study, we are investigating what occupational therapy practitioners are doing during therapy for children with autism and to see the effect of occupational therapy on brainwaves and behavior. We will identify differences in brainwaves in children with and without autism. You and your child will be asked to schedule one visit to the EEG lab at Ohio State University. Your visit will last about 2.5 hours and include an hour of EEG testing and one hour of paper-pencil game-like activities measuring attention. We need parent consent, and the parent/guardian will complete assessments about their child as well.

Could this study be right for you?

- Children with no autism or any other medical diagnosis - Your child is between 6 - 13 years of age

Age Range

6 and up

Official Title

Hepatitis C Virus Immunity in Women and Children

Purpose

This is a study to find out how pregnancy affects a mother’s immune system. (The “immune system” is the part of the body that fights germs.) This study is also to find out why some babies who are exposed to infections during pregnancy get infected and others do not.

To do this project we need to study some women and babies who are infected with the hepatitis C virus and others who are not. This will allow us to compare their immune systems.

Could this study be right for you?

You may be eligible to participate if you are:

PREGNANCY COHORT eligibility criteria:
1) Pregnant (enrollment preferably during 1st or 2nd trimester, but may occur as late as the delivery hospitalization)
2) HCV-RNA positive (#150) or HCV-RNA negative (#50)
3) Willing and able to attend all study visits

Exclusion criteria for mothers:
1) Inability to provide informed consent
2) Incarceration

Inclusion criteria for infants:
1) Child born to study mother

Exclusion criteria for infants:
1) In custody of county children’s services (Enrolled infants who are temporarily in custody of children’s services will not have further study blood draws, but lab results from blood tests ordered by their pediatrician may be followed to monitor the outcome of their HCV exposure. Infants who are later placed back in the custody of their mother or relative may be re-enrolled.)

NON-PREGNANCY COHORT eligibility criteria:
1) Willing and able to attend all study visits

Exclusion criteria:
1) Currently pregnant
2) Inability to provide informed consent
3) Incarceration

Official Title

Media Violence and Gun Violence

Purpose

Researchers want to examine the effects of movies on children aged 8 - 12 years. If your child joins this study, they will watch a 1-minute safety video at home and answer a short survey. At-home activities should take less than 20 minutes. Next, they will come to OSU campus for the lab part (parking is paid, mask wearing is required) with a same aged peer or sibling. There they will watch a movie clip for 20 minutes (rated PG) and afterwards be placed in a room containing toys and games that they can play with for another 20 minutes. The children will be videotaped so we can see what they do. Participation in the lab portion will take 50 – 60 minutes.

Could this study be right for you?

- Participants in the study will be children aged 8 - 12 years old - In order to participate in this study, your child must bring another child 8 - 12 years old. If you don't have two children within this age range, your child can bring a friend or relative.

Age Range

8 and up

Official Title

An Examination of the Diet Quality of Low-Income Children 6-24 months old

Purpose

The purpose of the research is to determine the dietary patterns and calculate the dietary quality of children 6 to 24 months of age and enrolled in childcare centers, WIC, and other places that serve parents of young children; and to identify the most important cultural, social, and economic factors influencing the dietary and feeding patterns of these children. The total amount of time you will be asked to volunteer for this study is 2 hours and 10 minutes.

Could this study be right for you?

- Parent or caregiver of a child 6 to 24 months old - Receiving WIC, SNAP, or similar benefits - Live in Franklin County, Ohio

Age Range

18 and up

Official Title

Play and Learning Across a Year

Purpose

The primary goal of this research is to learn how children and mothers interact at home and how that interaction and the home environment affect learning and development. (1) We will film you and your child playing and going about daily activities for an hour in your home (2) We will film the rooms in your home, create floor plans of the rooms and spaces that are accessible to your child, and record the noise level in your home (3) We may ask you questions about your child’s movement, language, emotion, health, toys and animals and media use in the home, and racial and ethnic background as well questions about family health, division of household labor, and education. (4) We may ask you and your child to play with a set of child-friendly toys for a few minutes. This single session study will last between 2 and 3 hours.

Could this study be right for you?

- healthy children less than 2 years old - children born full-term - only child living in household - primary language is English

Official Title

An Examination of the Diet Quality of Children Low Income Children from 3-5 Years of Age

Purpose

To determine dietary patterns and calculate dietary quality of young children enrolled in child care centers, WIC, and other places that serve parents and young children; and to identify the most significant cultural, social, and economic factors influencing the dietary and eating patterns of these children.

The total amount of time you will be asked to volunteer for this study is 2 hours and 10 minutes.

Could this study be right for you?

- Parents and/or caregivers must be at least 18 years of age
- Each household must qualify as low income status
- Each parent/caregiver must be fluent in English
- Each child must not have a medical condition requiring diet modifications
- Each child must be 3-5 years old

Age Range

3 and up

Official Title

An Examination of the Diet Quality of Low-Income Children from Birth to 6 Months Old.

Purpose

The purpose of the research is to determine the dietary patterns and calculate the dietary quality of infants and enrolled in childcare centers, WIC, and other places that serve parents of young children; and to identify the most significant cultural, social, and economic factors influencing the dietary and feeding patterns of these children.

The total amount of time you will be asked to volunteer for this study is 2 hours and 10 minutes.

Could this study be right for you?

- Parents or caregivers must be at least 18 years of age
- Each parent/caregiver must be fluent in English
- Each household must qualify as low income status based on the number of people in the household
- Children must be within 0-6 months of age
- Children must not have any medical condition requiring a modified diet

Official Title

Trauma and Neurobiological Threat Reactivity as Risk Factors for Alcohol Abuse in Youth

Purpose

This research study will look at how brain and behavioral responses to emotional prompts relate to future behaviors. This research is being done to better understand risk factors and behavior change in adolescents. The total time that you will be involved in this study is 15 hours including 4 in-person visits and online follow-up forms every 3-months for 2 years.

Could this study be right for you?

Eligibility Criteria includes: - 16-19 years old - No history of alcohol use disorder - History of Interpersonal Trauma - Voluntarily consumed at least 1 prior alcoholic beverage (partial list of inclusion criteria) Exclusion Criteria - Currently pregnant (positive pregnancy test), or trying to become pregnant (women) - Lifetime history of any substance use disorder (partial list of exclusion criteria)

Age Range

16 and up