Pippa Fitness Pessary Device Effectiveness and Safety Study

Official Title
Pippa Fitness Pessary Device Effectiveness and Safety Study
Purpose

The purpose of this study is to demonstrate the effectiveness and safety of the Pippa Fitness Pessary (device) when self-administered and used in a home environment.
 

Could this study be right for you?

. Be a female 18 years or older
· Live in or near Columbus, Ohio
· Consistently leak during light exercise
· Have no prior vaginal surgery

 

Age Range
18 years and up

PROMISE

Official Title
PRenatal and Obstetric Maternal Exposures and ISlet Autoantibodies in Early Life (PROMISE)
Purpose

The purpose of this study is to find out more about how health and exposures during pregnancy, such as having an infection, diet and growth may impact later risk of islet autoimmunity in the
child. We are also interested in finding out more about why having a father or sibling with type 1 diabetes increases risk of autoimmunity in the child than having a mother with type 1 diabetes.

Could this study be right for you?

Inclusion:
Pregnant women:
- who is between 8-24 weeks gestation with a singleton pregnancy
- have had type 1 diabetes for at least 12 months, or the father of the baby or a full sibling of the baby has type 1 diabetes
- is 18 years of age or older
- is willing to have blood collected and to complete questionnaires about prenatal exposures once per trimester during their pregnancy (up to 3 visits) and up to 12
weeks after they deliver their baby
- is willing to have their baby screened for genetic risk for type 1 diabetes, to complete online questionnaires, and to have their child followed for measurement
of islet autoimmunity according to the determined risk for type 1 diabetes, through 5-7 years of age.
o If low risk, two screenings: the first at 2 years of age and the second between 5-7 years of age
o If high risk, five screenings: every six months through 2 years of age, and one between 5-7 years of age

The father of the baby will also be asked to complete one visit during pregnancy but it is not mandatory.

Exclusion:
- Multiple Gestation pregnancy
- Mother unable to consent due to intellectual impairment
- Fetus with known medical issue that would affect study participation
- Surrogate / gestational mothers who are not biologically related to offspring they are carrying

Age Range
18 years and up

Breathing Training Program for Breast Cancer Survivors with Obesity

Official Title
Reducing exercise intolerance through inspiratory muscle training in obese breast cancer survivors (IMOCS)
Purpose

The purpose of this study is to better understand why some survivors of breast cancer have difficulty exercising. We also want to learn if breathing exercises can make it easier to tolerate exercise. 

Could this study be right for you?
  • Breast Cancer Survivor
  • Completed treatment within 6 months–5 years
  • Have obesity, defined as body mass index between 30-50 kg/m2
  • Can exercise independently
Age Range
18 years and up

Understanding Patient Experiences of Gestational Diabetes

Official Title
A Multi-Actor Examination of Gestational Diabetes Mellitus (GDM)
Purpose

This study aims to examine the experience of people who have been diagnosed or are currently living with gestational diabetes, including how they manage and make sense of their diagnosis. 

Could this study be right for you?
  • Aged 18 years or older
  • Must live in the state of Ohio
  • Must be currently pregnant and have been diagnosed with gestational diabetes OR must have been diagnosed with gestational diabetes during a recent pregnancy (within the last 12 months)
Age Range
18 years and up

Buckeye Concussion Knowledge Survey (BUCKS)

Official Title
BUckeye Concussion Knowledge Survey (BUCKS)
Purpose

The purpose of this study is to examine health outcomes in former Ohio State University athletes who played a varsity sport during their time at OSU. The objective is to determine whether athletes who sustained a concussion have different health outcomes than those who did not sustain a concussion. Any former OSU varsity athlete can participate in a 20-minute online survey.

Could this study be right for you?
  • Anyone who has played a varsity sport as an undergraduate student at OSU, and they have now graduated (i.e., OSU athlete alumni). There are no other restrictions in terms of age, sex/gender, type of sport, etc.
Age Range
18 years and up

Treatment of Chronic Hepatitis C Virus During Pregnancy

Official Title
Safety, Tolerability, and Outcomes of Velpatasvir/SofosbuviR in Treatment of Chronic Hepatitis C Virus during Pregnancy (STORC), pregnant woman
Purpose

This study involves evaluating a medication for hepatitis C in pregnant women. 

If you are a pregnant woman with chronic hepatitis C and you join the study, you are consenting to enroll yourself and your baby after he/she is born.

Maternal participants will have 7 visits over approximately 7 months. Infant participants have four visits over approximately the first year of life.

Could this study be right for you?

(This is not a complete list)  

- Must be  18 - 45 years of age

Chronic HCV infection of at least 6 months

- Singleton pregnancy at 20 + 0 to 30 + 0 weeks’ gestation

Documented negative Hepatitis B testing for current infection (negative HBsAg test) prior to enrollment

If living with HIV, must be on antiretroviral therapy

 

Exclusion Criteria (not a complete list)

Plans to relocate away from the study site area in the next 16 months and unable/unwilling to return for study visits

History of cirrhosis

Known fetal chromosomal abnormality prior to enrollment

Age Range
18 - 45

Blood Pressure Health for Black/African American Women Caregivers

Official Title
Addressing the double jeopardy of stress and hypertension among African American female caregivers of persons living with Alzheimer’s disease and related dementias (R21)
Purpose

The purpose of this study is to determine the feasibility of a group delivered intervention for stress and blood pressure in African American women caregivers.

Could this study be right for you?
  • Diagnosis of HTN treated with an antihypertensive medication or risk of HTN that includes obesity and high cholesterol
  • Age 40 and older
  • A caregiver rating of the PLWD of 2 or greater on the Alzheimer’s Dementia-8 scale
  • Caregiver provides unpaid care to a PLWD at least 10 hours per week or assists with at least one instrumental activity of daily living
  • Self-identifies as Black/African American
  • English speaking
  • Access to a telecommunications device such as the internet via desktop, laptop/tablet, smartphone, or telephone
Age Range
40 and up

Assessing Responses to Exercise in the Heat in Trained Women

Official Title
Assessing Responses to Exercise in the Heat in Trained Women
Purpose

The purpose of this research study is to conduct exercise in hot and neutral environments on women who are aerobically trained and resistance trained to characterize and compare responses across physiologic, perceptual, and neurocognitive domains. Our rationale for this investigation is that its completion would provide evidence as to how women of different fitness backgrounds respond to exercise in the heat and how that response is different from exercising in thermoneutral conditions to better describe how the female body tolerates exercise in the heat with implications for those in recreation, competitive sports, and occupation that expands to emergency and military services.

Could this study be right for you?

Aerobically Trained: having a measured aerobic capacity in the 80th percentile according to age

Resistance Trained: able to squat 120% and bench press 60% of their body weight.

Unacclimatized: participants had not been consistently exposed to hot conditions (i.e., sauna, hot yoga, etc.) in the past 2 months.

Age Range
18 - 35

Young Women’s Health Study

Official Title
An Intervention Study about Primary Care Algorithms for Early Identification of Young Women with von Willebrand Disease
Purpose

Researchers at Nationwide Children’s Hospital are seeking volunteers to be a part of a study looking at how to best screen for bleeding disorders in young women.

Participants will be asked to undergo a finger prick blood test and complete questionnaires. If their survey answers suggest they have heavy menses or abnormal bleeding, they will also be asked to have a blood draw on the same day.

Could this study be right for you?
  • Are 9 to 21 years old
  • Have had your first menstrual cycle
Age Range
9 - 21

An Observation Study to Evaluate Retina Eye Picturing in Women with Preeclampsia

Official Title
Remote monitoring of retina vasculature in women with preeclampsia: novel biomarker for disease severity
Purpose

The overall goal is to evaluate whether pictures we take of the retina of the eye can be used to detect preeclampsia and its severity.

Your participation will be from your enrollment visit, until 2-4 months after delivery, which will be no more than 32 weeks.

Could this study be right for you?

Inclusion criteria for normal blood pressure healthy pregnant women:
• Women aged 18 years or older
• Pregnant females at enrollment being >= 24 0/7 of pregnancy
• Able and willing to provide consent and willing to conduct the postpartum follow-up
• Normal blood pressure at enrollment
Inclusion criteria for Preeclampsia Pregnancies with severe features:
• Women aged 18 years or older
• Pregnant female at enrollment between 24 0/7 and 33 6/7 of pregnancy
• Able and willing to provide consent and willing to conduct the postpartum follow-up
• All subjects must be Preeclampsia (dangerous high blood pressure in pregnancy) diagnosed.

Exclusion Criteria for both groups:
• Known chromosomal, genetic, major malformations, fetal demise.
• Past medical history of hypertension >5 years, pre-gestational diabetes, or know retinal disease
• Pregnant for twin, triplets or higher
• Participating in another intervention study that influences the outcomes in this study.

Age Range
18 and up