The main reason for you to take part in this study is not to treat you for your condition but to help in answering the following research questions:
• Whether baricitinib is better than placebo in the treatment of patients with severe alopecia areata (AA)
• The safety of baricitinib and any side effects you may have when you take it.
- Are at least 18 years and ≤60 years for males (≤70 years of age for females) at
the time of informed consent
- Are able to read, understand, and give documented (electronic or paper
signature) informed consent
- Current AA episode of more than 6 months’ duration and hair loss
encompassing ≥50% of the scalp
- No spontaneous improvement over the past 6 months
This study is being done to assess the effects of the experimental study drug (ANB019) in patients with PPP.
- Must have a clinical diagnosis of PPP for at least 6 months prior to screening
- Must have active pustules on palms and/or soles of feet
- BMI must be within the range of 18-36 kg/m2
- Subjects must be in otherwise good health
- Must not have any suspected autoimmune disorder or immune deficiency
- No major surgeries in the past 4 weeks
- No history of malignancy in the past 5 years
- No history of drug, alcohol, or other substance abuse
This study examines the financial hardship experienced by adult children who provide care to parents with Alzheimer's and dementia. The research questions for this study explore how adult children navigate the economic and financial hardship associated with being a caregiver: financial sacrifices or economic hardships they may face due to caregiving responsibilities and how they think this will affect them in the future.
Eligible participants include adult children in Central Ohio (from urban and rural areas) who are caregivers to a parent or parent-in-law with Alzheimer's or dementia.
Smokers (age 21-45) are wanted for an Ohio State University study that provides cigarettes with different filters and that may provide access to other tobacco or nicotine products. Smokers should be willing to undergo two medical procedures called a bronchoscopy.
- Must be 21 - 45 years of age
- Must be a smoker
Smokers are wanted for an Ohio State University study that provides cigarettes with different filters and that may provide access to other tobacco or nicotine products.
- You must be a smoker
- At least 21 years of age
This research study aims to determine the effects of a noninvasive form of brain stimulation on alertness for night shift workers.
• You are age 18 to 65
• You are currently working the night shift at least 3x/week
• You are suffering from sleepiness at work
• You do not have significant heart and lung problems
• You work within the Columbus, OH area
The purpose of the current study is to characterize the perspectives of cancer patients who have undergone a cancer-directed surgery on the role of spirituality and/or religion during their cancer journey in order to better define the desired access to related resources during cancer care. Results from this study will inform future research aimed at addressing patient-centered spirituality/faith needs of cancer patients.
If you’ve had or will have surgery to treat a cancer diagnosis, you can help researchers at Ohio State examine how patient spirituality and/or religion influences the cancer journey by taking an online survey.
Participants should be:
• Over 18 years old.
• Diagnosed with cancer (all types).
• At least four months past the initial cancer diagnosis.
• Underwent or will receive a surgical procedure related to their cancer
• Able read and write in the English language.
This study will help researchers to learn more about mental health for youth with intellectual disabilities. The purpose of our study is to develop a diagnostic interview to assess mental health issues in youths with Intellectual Disabilities. The instrument would address a significant need and allow for more accurate estimation of mental disorders in the Intellectual Disabilities population.
We are recruiting youths with Intellectual Disabilities aged 14-21, and their caregivers as well. Each participant would take part in one individual session of approximately 60-90 minutes (with breaks) at the Ohio State University Nisonger Center. Youths will be asked to respond to a set of interview questions about mental health, including providing feedback on a set of illustrations related to the interview questions about emotions, feelings, and behaviors. Parents or caregivers will be asked to provide feedback on the interview questions asked of youth.
You may be eligible to participate in the study if you are:
--14 to 21 years old AND have been diagnosed with an Intellectual Disability
Youths will be asked to respond to a set of interview questions about mental health, including providing feedback on a set of illustrations related to the interview questions about emotions, feelings, and behaviors. Parents or caregivers will be asked to provide feedback on the interview questions asked of youth.
This study aims to understand people’s experiences with contraceptive sterilization (such as tubal ligations or vasectomies).
The purpose of this study is to better understand how adults decide to use sterilization as
their main form of birth control. By examining sterilization decisions, this study will
provide a better understanding of how individuals describe and explain their decision
In this study we are interested in learning how people discuss these decisions with their partner, as
well as everyday interactions with their partner, other forms of birth control, and attitudes
about gender more generally.
-Have used tubal ligation or vasectomy as primary contraception, WITHIN the last five (5) years
Participants will be asked to answer a series of questions regarding their experience with
sterilization. Interviews will be digitally recorded by audiotape and will remain
confidential. The duration of the interview will last approximately one hour to one hour
and thirty minutes.
The purpose of this study is to find out how to best distribute physical therapy sessions for your children with significant motor delays.
Participants will receive 40 hours of physical therapy. Participants will be randomly assigned to one of the three treatment groups: intensive, moderate or weekly.
- Children ages 6 months to 24 months of age
- Has a diagnosis of cerebral palsy or an acquired brain injury prior to age of 24 months.
- Has persistent delays in motor skills
- Ability to participate in outpatient physical therapy and attend visits consistently
The intensive group will receive physical therapy 2 hours per day, 5 days per week for 4 weeks followed by a 16 week break from outpatient physical therapy. The intermediate group will receive physical therapy 2 hours per day, 3 days per week for 6.6 weeks followed by a 13 week break from outpatient physical therapy. The weekly group will receive physical therapy for 2 hours per day, 1 day per week for 20 weeks