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Pain Response Study in Autistic and Non-autistic Adults Ages 30-70.
Official Title Pain Sensitivity and Endogenous Pain Modulation in Autistic Adults (R21)Purpose
The purpose of this project is to study how pain may differ in adults with or without autism. Our goal is to study whether or not pain is experienced or felt differently in autistic adults compared to non-autistic adults.
Participants will be screened by phone. After meeting the initial screening criteria, the study visit will be scheduled. Participants can expect one study visit lasting 2-3 hours with time built in for breaks.
Could this study be right for you?
- Not currently on any daily pain medications
Age Range
30 - 70 years -
FAVOR Study - Aging Influences on Balance and Falls
Official Title Linking Age, Balance, Vestibular Function, and FallsPurpose
The purpose of this study is to learn how aging in different sensory systems, including the vestibular system (that portion of the inner ear that measures both motion and orientation of the head), influences maintaining balance while standing and walking, and contributes to fall risk.
Could this study be right for you?
- Must be able to stand
- No leg or foot amputations
- No lower limb braces
- Not currently feeling dizzy/lightheaded
- Not currently pregnant by self-report
- Due to potentially nauseogenic nature of some motions and to protect fetus and mother, pregnant women will also be excluded from this study
- Weight <= 275 pounds
- No past or current history of:
- Severe head trauma or traumatic brain injury
- Any vestibular disorder (e.g., Meniere’s Disease, Vestibular Migraine, Unresolved BPPV/BPPN, Vestibular hypofunction, except that due to aging, PPPD) as assessed using clinical diagnostic tests described in proposal
- History of seizures
- Neurologic illness or conditions known to impact vestibular or balance function(e.g., stroke, neurodegenerative disorders, demyelinating illness)
- Major psychiatric (e.g., panic disorder, psychosis, etc.) disorder
- Any of the following eye diseases or conditions: amblyopia (or “lazy eye”) or history of amblyopia, diagnosis of age-related macular degeneration, retina dystrophy, glaucoma, cataracts, or any other eye condition that limits vision to worse than 20/40
- Recent (<6 months) orthopedic injuries of the lower extremities (e.g., plantar fasciitis, ankle, knee or hip injury, back strain/herniated disc, …).
- Upper extremity injuries requiring current sling immobilization
- Recent surgery
- Any other severe health problem (heart disease, pulmonary disease, cancer, etc.).
- Vision in both eyes must be better than 20/40 with best correction
- Outer and/or middle ear pathologies
- Otologic pathologies or diagnoses (e.g. Meniere’s disease, otosclerosis, conductive or mixed hearing losses)
- Must be able to walk unassisted for 30 minutes
- No current use of ambulatory assistive devices
- Normal hearing bilaterally, air conduction pure-tone thresholds ≤ 25 dB HL at all octave frequencies between 250 and 8000 Hz
- Bilaterally, symmetric sensorineural hearing loss with four-frequency pure-tone average (500, 1000, 2000, 4000) less than 71 dB HL
- If interested, please go to go.osu.edu/vestibular to be screened for eligibility
Age Range
18 - 89 years -
The Perceptions of Gen Zs Regarding the Dietary Guidelines for Americans (DGA)
Official Title The Knowledge and Perceptions of Gen Zs Regarding the Dietary Guidelines for AmericansPurpose
- Use ideas from Social Cognitive Theory to describe Gen Zs regarding the Dietary Guidelines for Americans (DGA) 2020 to 2025
- Explain what Gen Z knows and believes regarding the MyPlate recommendations for healthy eating related to:
- Filling half their plate with fruit and vegetables
- Filling one-quarter of their plate with lean protein, and varying the sources of protein
- Filling one-quarter of their plate with grains, making half of the grains whole grains
- To describe the associations between demographic variables (ethnicity, education, household income, and home environment) and Gen Zs perceptions and knowledge of the DGA
Could this study be right for you?
18 to 28 years old
Live in the US
English speaker
Have access to a device that supports Zoom
Age Range
18 - 28 years -
Radiotracer Imaging of Lower Extremity Skeletal Muscle Perfusion in Patients with Peripheral Arterial Disease (PAD)
Official Title Radiotracer Imaging of Lower Extremity Skeletal Muscle Perfusion in Patients with Peripheral Arterial DiseasePurpose
The purpose of the study is to evaluate the usefulness of a new imaging method that measures blood flow to the calves and feet.
A group of patients with a history of peripheral artery disease (PAD) will have blood flow to their legs and/or feet evaluated using a nuclear imaging technique called positron emission tomography (PET). A separate group of patients with PAD who are scheduled to undergo a revascularization procedure on their leg (such as balloon angioplasty, stent placement, or bypass surgery) will undergo PET imaging before and after their surgical intervention to evaluate how the intervention improved blood flow to their leg.
In addition to patients with PAD undergoing imaging studies, we will also recruit and image healthy volunteers to establish a normal healthy database of blood flow values for our new imaging method.
Patients with PAD will be evaluated for up to 18 months after their imaging study visit to evaluate how their blood flow values are related to their clinical outcomes, such as rates of diabetic wound healing and amputation. Outcomes will be monitored through medical chart review and through follow-up visits at OSU-affiliated clinics.
Could this study be right for you?
We are interested in recruiting healthy volunteers with no known history of cardiovascular disease or diabetes mellitus.
OR
Patients with previously diagnosed peripheral artery disease.
Age Range
30 years and up -
Making Colorectal Cancer Screening Simple and Accessible Through Technology
Official Title Digital Transformation of CRC Screening: Revolutionizing Access and Saving LivesPurpose
The purpose of this study is to conduct usability testing to evaluate ease of use and overall user experience of a website designed to promote colorectal (CRC) awareness and screening uptake among adults 45-64.
Could this study be right for you?
Inclusion Criteria: Eligible participants will 1) be between the ages of 45-64, 2) at average risk for CRC and 3) from diverse racial/ethnic and socioeconomic backgrounds
Those who are ineligible fall under the following categories:
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Age: Individuals outside the age range of 45-64 will be excluded
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Pregnancy Status: Pregnant individuals will be excluded from the study. since CRC screening is not recommended for pregnant individuals
Age Range
45 - 64 years -
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An Investigational New Drug for the Treatment of Alzheimer’s Disease
Official Title A Phase 1, Randomized, Double-Blind, Placebo-Controlled Study Evaluating the Safety, Tolerability, and Pharmacokinetics of Single Escalating Doses of LH-001 in Healthy SubjectsPurpose
The purpose of this study is to evaluate the safety and tolerability of an investigational new drug in healthy participants aged 18-60 years.
Could this study be right for you?
- In good health and BMI (ratio of body weight to height) between 18-29.9 kg/m2
- Willing to participate in various research assessments including blood collection, urine collection, electrocardiogram, and vital signs
- Willing to stay overnight (~30 hours) in the OSU Hospital Clinical Research Center
- If sexually active, willing to utilize highly effective birth control during the study period
- Not currently pregnant or breast-feeding
- No significant medical condition involving any major organs (heart, lung, liver, brain, or endocrine)
- No to any of the following: alcohol or substance abuse, spleen problems, or drug hypersensitivity
- No history of or undergoing treatment for: major psychiatric illness, seizures, or autoimmune disease
- Not currently taking immunosuppressive drugs
- No active Hepatitis B, Hepatitis C, or HIV
- No cancer history within 5 years (squamous and basal cell skin cancer excluded)
Age Range
18 - 60 years -
MOMI Study
Official Title The mom and infant outcomes (MOMI) study: A trial of perinatal outpatient delivery systemsPurpose
To improve our ability to provide the best possible care to every mom and infant, we are testing two different models of primary care during the first year after childbirth.
Could this study be right for you?
- You may qualify if you’re currently pregnant – AND – you’ve ever had high blood pressure, diabetes, depression, or anxiety, including during pregnancy.
If you participate, you’ll be randomly assigned to an Ohio State location that delivers one of two models of care. Providers at all locations can help you manage your health, but the models differ in several ways.
- You’ll complete three study visits with surveys, several measurements, and blood and hair sampling. We’ll collect cord blood and review medical records.
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Sleep Restriction and Ketone Supplements
Official Title Strategies to Augment Ketosis: Ketone Conferred Resiliency Against Sleep Restriction (STAK-Sleep)Purpose
To examine if drinking a ketone supplement, twice a day, can improve brain, digital shooting, and physical performance during short-term sleep restriction (4 nights, 50% of normal sleep).
Could this study be right for you?
- Healthy
- Age: 18 - 40 years old
- BMI: 20-35 kg/m2
- No diagnosed sleep disorders
- Not consuming a ketogenic diet
Age Range
18 - 40 years -
Understanding the Neurodevelopmental Effects of Youth Tackle Football Participation
Official Title Understanding the Neurodevelopmental Effects of Youth Tackle Football ParticipationPurpose
In this study we are aiming to identify risk factors for higher exposure to football-related neurotrauma in youth tackle football players and to determine the effects of football-related neurotrauma exposure on neurodevelopment in children with no previous tackle football participation.
For this specific posting, we are looking for boys ages 8-12 who are non-athletes or athletes who play non-contact sports to serve as control subjects for our fMRI study.
Could this study be right for you?
We are looking for boys ages 8-12 who are either non-athletes or do not participate in any contact sports.
- Boys must have no metal implanted in the body
- Have no prior history of head trauma
- Have no serious health or mental health diagnoses
- Must not have a fear of enclosed spaces
Age Range
8 - 12 years -
A Study Evaluating How Alcohol Affects Thinking and Decision Making
Official Title Impulsivity Domains and Subjective ResponsePurpose
The purpose of this study is to examine the degree to which different ways of thinking and decision making – measured using computer tasks and questionnaire – relate to how people feel after a dose of alcohol. By doing this study, we hope to learn about the relationships between decision making and responses to alcohol.
Could this study be right for you?
Inclusion criteria include:
- Ages 21-25
- English language Fluency
Exclusion criteria include:
- Any serious medical problems (i.e., liver disease, cardiac abnormality, pancreatitis, diabetes, neurological problems, gastrointestinal disorders, abnormal kidney function)
- Body weight < 110 or > 210 pounds
- Current medical or psychiatric condition requiring medication for which alcohol consumption is contraindicated
- Lifetime history of schizophrenia or other psychotic disorder
- Substance Use Disorder other than alcohol
Exclusion Criteria varies, please contact Study Coordinator.
Age Range
21 - 25 years