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Studying a New Method to Evaluate Blood Flow in Patients with Peripheral Artery Disease (PAD)
Official Title Radiotracer Imaging of Lower Extremity Skeletal Muscle Perfusion in Patients with Peripheral Arterial DiseasePurpose
The purpose of this study is to study a new method to evaluate blood flow to the calves and feet. We hope this information can help evaluate the effectiveness of treatments and predict clinical outcomes.
Could this study be right for you?
-Diagnosis of Peripheral Arterial Disease (PAD) OR leg symptoms, such as muscle pain or cramping AND/OR foot wound that has required medical consultation
- Healthy volunteers must:
- Be at least 40 years of age
- Have no history of cardiovascular disease (including high blood pressure)
- Have no history of diabetes mellitus
- Be a non-smoker
- Have normal BMI
Age Range
40 and up -
MeSo Study
Official Title Mechanisms of Self and Other Evaluation (MeSO Study)Purpose
The purpose of this study is to better understand the way the brain works in people who have depression and people who have previously been depressed. We are also testing healthy subjects for comparison. We hope our findings will lead to better ways to diagnose and treat mood disorders in the future. Participation involves an initial phone call and a 2 to 4 hour visit to find out if you are eligible. This visit will include completing questionnaires and interviews. If eligible, participants will have a second 3-5 hour visit for an MRI scan. Two months after the scan, participants will complete daily online questionnaires for 7 days. This process is repeated 2 months later (4 months after the scan).
Could this study be right for you?
You may be eligible for this study if you:
- Are between the ages of 18-40
- Are right-handed
- Do not have a history of neurological disorders (e.g., seizures, head injury, etc.)
- Do not have major medical problems (e.g., stroke, heart disease, high blood pressure, endocrine disorders, etc.)
- Have normal vision, vision that is corrected to normal with glasses or contacts
- Are willing and able to undergo fMRI scanning (not claustrophobic, no non-removable metal in your body)
- Are not pregnant
Age Range
18 and up -
A Study Evaluating Alcohol Use and Anger
Official Title Aggression and Social-Emotional Information Processing: Neural Correlates During Alcohol Intoxication (Columbus Brain Activity Study or CBA)Purpose
The purpose of this study is to see how alcohol changes brain activity in different groups of study participants who currently drink at least 10 drinks a week and who have (or do not have) “anger issues”. Brain activity will be measured by Magnetic Resonance Imaging (MRI).
Total time you will be in the research study will be for about 4-8 weeks from your initial visit.
Could this study be right for you?
- Healthy men and women 21-55 years of age
- Drink on a regular basis (~ 10 alcoholic beverages per week)
- With a current history of "anger issues" and/or "alcohol issues"
- Able to complete study sessions during the week
Age Range
21 - 55 -
Adult Eye Tracking Study
Official Title Comprehensive Protocol for Cognitive Development ResearchPurpose
The purpose of this study is to better understand learning, memory and attention development from childhood to adulthood using eye-tracking techniques.
This study will include one lab visit which will take place on Ohio State's main campus and will last approximately 40-60 minutes.
Could this study be right for you?
Eligibility Criteria:
- Must be 18 and 35 years of age
- Have normal or corrected to normal vision
Age Range
18 and up -
A Study Evaluating Decision-making for Young Adults, Older Adults, and Adults with Early Alzheimer’s Disease and Mild Cognitive Impairment
Official Title Modeling Cognition and AgingPurpose
The goal of this study is to develop models to better understand decision-making for young adults, older adults, and adults with early Alzheimer’s disease and Mild Cognitive Impairment. This study involves making simple decisions (such as “are there more blue dots or more yellow dots?”) on a computer. Healthy volunteers will also complete basic tasks such as solving puzzles, questionnaires involving numbers, and will be asked to provide basic demographic and health information.
Could this study be right for you?
You may be eligible for this study if:
- You are ages 18-25 OR
- You are age 60-90 and have NOT been diagnosed with a memory disorder OR
- You are age 60-90 and HAVE been diagnosed with either Mild Cognitive Impairment OR mild Alzheimer's disease
- You are a native English speaker
- You are able to see a computer screen and use hands on keyboard/screen
Age Range
18 and up -
Transitioning From Booster Seats to Seat Belts
Official Title Booster Seats InterviewPurpose
To explore how parents make the decision on transitioning their children from booster seats to seat belts; what factors may influence parents’ decision on the transition.
Could this study be right for you?
Inclusion criteria:
- At least 18 years of age
- A parent or legal guardian who is responsible for transporting their child routinely
- Have a child who stopped using booster seats within 1 year prior to the interview date, and the child who made the transition must be the first child of the parent
- Drive with a child at least once per week
- In good general health
- Fluent in English
Age Range
20 and up -
Decision-Making Abilities and Testamentary Capacity Among Older Adults
Official Title Decision-Making Abilities and Testamentary Capacity Among Older AdultsPurpose
The overall goal of this research is to examine factors such as social resources, personality characteristics, and neurocognitive functioning in relation to decision-making abilities testamentary capacity among healthy older adults.
Another purpose of this research study is to evaluate the impact of Problem-Solving Treatment-Primary Care (PST-PC), a cognitive-behavioral therapeutic approach, on decision making among healthy older adults. PST-PC involves a seven-step model, in which participants identify problems to be solved, discuss and evaluate different resolutions to reach desired goals; create action plans to accomplish determined goals; and evaluate their effectiveness in resolving designated problems.
We will compare the effectiveness of PST-PC on individuals who will not receive any intervention.
A no treatment control group of older adult participants will also be recruited to compare the effectiveness of PST-PC to individuals who do not receive the intervention. This no treatment control group will composed of participants who do not receive the PST-PC sessions.
Could this study be right for you?
Inclusion Criteria:
- adults aged 65 and older
- Must be independently-living and community-dwelling
- Participants must be willing to undergo a health interview to rule out outstanding medical and psychiatric conditions
- Adequate sensory abilities
Exclusion Criteria:
- A history of psychiatric illness necessitating inpatient treatment
- Participants with self-reported depression and/or anxiety exceeding mild levels of clinical severity
Age Range
65 and up -
A Study Utilizing Functional Feedback for Focused Ultrasound Thalamotomy for Tremor Surgery
Official Title Functional Neuroimaging Feedback for Focused Ultrasound Thalamotomy for Tremor SurgeryPurpose
The goal of this study is to understand if there are any changes to the connections between the cells in the brain before and after the ultrasound surgery for the treatment of Essential Tremor. This will be done by comparing patients who have had ultrasound surgery and Essential Tremor with healthy individuals. This study may help us to better target the tremor region in the brain during the ultrasound surgery.
Could this study be right for you?
- You must be between the ages of 40 and 85
- Willing to have MRI imaging of the brain
Age Range
40 and up -
Healthy New Albany: Breast Cancer Project
Official Title Healthy New Albany: Breast Cancer ProjectPurpose
Determine the feasibility of delivering a community-based, lifestyle weight management intervention in producing meaningful improvements in weight loss and relevant clinical and patient-reported outcomes in Breast Cancer survivors.
Could this study be right for you?
- Female breast cancer survivor within 60 months after cessation of active treatment.
- Overweight/Obese (BMI > 25).
- Ability to understand and willing to sign a written informed consent.
- Willing and physically able to participate in physical activity.
- Obtain physician consent via primary care physician and/or treating oncologist.
Age Range
30 and up -
A Study for Night Shift Workers
Official Title Transcranial Direct Current Stimulation Therapy for Sleepiness Related to Shift Work Disorder (tDCS-SWORD)Purpose
This research study aims to determine the effects of a noninvasive form of brain stimulation on alertness for night shift workers.
Could this study be right for you?
- You are age 18 to 65
- You are currently working the night shift at least 3x/week
- You are suffering from sleepiness at work
- You do not have significant heart and lung problems
- You work within the Columbus, OH area
Age Range
18 and up