Decision-Making Abilities and Testamentary Capacity Among Older Adults

Official Title
Decision-Making Abilities and Testamentary Capacity Among Older Adults
Purpose

The overall goal of this research is to examine factors such as social resources, personality characteristics, and neurocognitive functioning in relation to decision-making abilities testamentary capacity among healthy older adults.

Another purpose of this research study is to evaluate the impact of Problem-Solving Treatment-Primary Care (PST-PC), a cognitive-behavioral therapeutic approach, on decision making among healthy older adults. PST-PC involves a seven-step model, in which participants identify problems to be solved, discuss and evaluate different resolutions to reach desired goals; create action plans to accomplish determined goals; and evaluate their effectiveness in resolving designated problems.

We will compare the effectiveness of PST-PC on individuals who will not receive any intervention.

A no treatment control group of older adult participants will also be recruited to compare the effectiveness of PST-PC to individuals who do not receive the intervention. This no treatment control group will composed of participants who do not receive the PST-PC sessions.

Could this study be right for you?

Inclusion Criteria:
-adults aged 65 and older
- Must be independently-living and community-dwelling
- Participants must be willing to undergo a health interview to rule out outstanding medical and psychiatric conditions
- Adequate sensory abilities

Exclusion Criteria:

- A history of psychiatric illness necessitating inpatient treatment
- Participants with self-reported depression and/or anxiety exceeding mild levels of clinical severity

Age Range
65 and up

A Study to Evaluate If Real-Time Visual Feedback on Breathing Influences Time to Exhaustion

Official Title
The influence of receiving real-time visual feedback on breathing during treadmill running to exhaustion
Purpose

The purpose of this research is to assess if receiving real-time visual feedback on your breathing pattern during a run has any influence on time to exhaustion.

The feedback will be provided through animations on a screen placed in front of the treadmill that open and close as the chest and abdomen expand and contract. Research has shown that you want the chest and abdomen to expand and contract at the same time to achieve the most efficient breathing possible, meaning you will want the animations to open and close at the same time.

The ultimate objective is to see if this feedback allowed the participant to last longer until reaching their exhaustion point.

Could this study be right for you?

- Healthy adults who run 5 to 20 miles per week
- Have NOT been injured while running in the past six months
- Have NOT been medically diagnosed with breathing deficiencies
- must be age 18 or older
Those who are interested in participating will be directed to complete a survey, found at go.osu.edu/RunningAndBreathing, to ensure that they meet the previously mentioned criteria.

Age Range
18 and up

A Study Utilizing Functional Feedback for Focused Ultrasound Thalamotomy for Tremor Surgery

Official Title
Functional Neuroimaging Feedback for Focused Ultrasound Thalamotomy for Tremor Surgery
Purpose

The goal of this study is to understand if there are any changes to the connections between the cells in the brain before and after the ultrasound surgery for the treatment of Essential Tremor. This will be done by comparing patients who have had ultrasound surgery and Essential Tremor with healthy individuals. This study may help us to better target the tremor region in the brain during the ultrasound surgery.

Could this study be right for you?

- You must be between the ages of 40 and 85
- Willing to have MRI imaging of the brain

Age Range
40 and up

COMET2 Bronchoscopy: A Study on Filter Ventilation and Product Standard

Official Title
Consortium on Methods Evaluation Tobacco (COMET): Filter Ventilation and Product Standard – COMET2 Bronchoscopy study
Purpose

Smokers (age 21-45) are wanted for an Ohio State University study that provides cigarettes with different filters and that may provide access to other tobacco or nicotine products. Smokers should be willing to undergo two medical procedures called a bronchoscopy.

Could this study be right for you?

- Must be 21 - 45 years of age
- Must be a smoker

Age Range
21 and up

A Study to Assess the Removal of Filter Ventilation on Smoking Behavior and Biomarkers (COMET2)

Official Title
Clinical trial to assess the removal of filter ventilation on smoking behavior and biomarkers (COMET2)
Purpose

Smokers are wanted for an Ohio State University study that provides cigarettes with different filters and that may provide access to other tobacco or nicotine products.

Could this study be right for you?

- You must be a smoker
- At least 21 years of age

Age Range
21 and up

A Study for Night Shift Workers

Official Title
Transcranial Direct Current Stimulation Therapy for Sleepiness Related to Shift Work Disorder (tDCS-SWORD)
Purpose

This research study aims to determine the effects of a noninvasive form of brain stimulation on alertness for night shift workers.

Could this study be right for you?

• You are age 18 to 65
• You are currently working the night shift at least 3x/week
• You are suffering from sleepiness at work
• You do not have significant heart and lung problems
• You work within the Columbus, OH area

Age Range
18 and up

Metabolism Research Study--Healthy Volunteers Needed

Official Title
Adipocyte-T Cell Interactions Modulate Adipose Inflammation and Insulin Sensitivity Following Weight Gain
Purpose

The purpose of this research study is to better understand the role of fat tissue, how cells in fat tissue communicate, and determine what signals specific cells use to cause inflammation and insulin resistance during weight gain. This may help researchers better understand the process that happens in Type 2 Diabetes.

As a result, through the course of six--nine weeks, participants will be asked to gain at least 10% of their starting body weight. A dietitian will meet with participants to give advice to help with meeting the study weight gain goals, as well as provide additional meal vouchers and supplemental shakes as needed. Following the study, participants will receive guidance how to lose the weight they've gained if they would like to do that.

Could this study be right for you?

You may be eligible if you:
- Are 18-60 years of age
- Are lean; Have a BMI 18-24.9 kg/m2 (*see link below for calculating your BMI --Body Mass Index)
- Have healthy levels of cholesterol and triglycerides (These will be tested at screening)
- Are a non-smoker
- Are non-diabetic
- Are free of chronic illness
- Are not pregnant or breastfeeding

*If you want to calculate your BMI https://www.cdc.gov/healthyweight/assessing/bmi/adult_bmi/english_bmi_c…

Exclusion Criteria:
- Fasting triglycerides > 150 mg/dL or nonfasting triglycerides ˃ 250 mg/dl
- LDL-Cholesterol level > 150 mg/dL,
- Presence of significant anemia (hemoglobin <10.0 gm/dL),
- Currently or planning to take blood thinners ,
- Current smokers
- Have taken steroids or anti-inflammatory meds for >6 months in the last 6 months
- >10% body weight loss within 3 months of enrollment
*Other exclusions may apply

Age Range
18 and up

Rheumatology Biorepository-- For Healthy Volunteers AND those with Autoimmune and Rheumatic Disorders

Official Title
The Ohio State University Rheumatology and Immunology Biorepository
Purpose

This study is being done to provide resources for future studies involving autoimmune and rheumatic disorders, such as systemic lupus erythematosus, rheumatoid arthritis, osteoarthritis, Sjogren’s syndrome, vasculitis, and undifferentiated connective tissue diseases. The samples and data collected will be stored and used in the future to learn more about rheumatic and autoimmune disorders. Healthy volunteers are also being recruited.

Could this study be right for you?

- 18 years of age or older

If you decide to participate in this study, you will be asked to provide some samples*.
The samples you can provide for this study could be any or all of the following:
• Blood (up to approximately 10 tablespoons)
• Urine
• Stool
• Saliva (approximately 2 teaspoons)
• Skin biopsy
• Oral mucosa biopsy
• Medical waste (such as skin or synovial fluid)

*You can choose which types of samples you would like to provide.

Age Range
18 and up

A Study for Those with Chronic Pancreatitis - The PROCEED Study

Official Title
Prospective Evaluation of Chronic Pancreatitis for Epidemiologic and Translational Studies PROCEED Study)
Purpose

This study is done for researchers to understand pancreatitis and learn how the disease progresses naturally over time.

From the results of this study, researchers hope to develop some lab tests to support early diagnosis of chronic pancreatitis and to also discover any genetic factors that may affect your chances of developing chronic pancreatitis. The results of this study may also provide information that will open opportunities for new drug discovery.

Could this study be right for you?

• You have a history of acute or chronic pancreatitis OR
• You have experienced pain in your abdomen that a doctor has suggested could be due to pancreatitis
• You are between the ages of 18 and 75

Age Range
18 and up

Parent-Infant Eye Tracking Study for Children With and Without Hearing Loss

Official Title
Development of Parent-Child Interactions
Purpose

This study will examine how a child’s hearing loss may affect the dynamics of parent-child interactions. The study will observe how normal-hearing and hearing-impaired child learn novel words during videotaped parent-child interactions.

Individual study visits may last 30-45 minutes, and there may be multiple study visits per year.

Could this study be right for you?

- Families with children 9 months to 6 years of age
- Children who do and do not have hearing loss may be eligible to participate in this study