A Study about Booster Seat Comfort
The purpose of this study is to determine how specific booster seat features, including seat pan geometry (booster height and length) and the inclusion of armrests, influence occupant comfort in belt-positioning booster seats (BPBs). This will be achieved through an analysis of comfort quantification methods and occupant posture and behavior under different booster conditions.
The duration of this study is two hours long.
- Must be able to sit for 30 minutes at a time
- No allergy to athletic tape
A Randomized Trial to Evaluate Sequential vs Simultaneous Spectacles plus Patching for Amblyopia in Children 3 to <13 Years Old
The purpose of this study is to evaluate if treating amblyopia (lazy eye) with glasses and patching at the same time improves vision as well as treating amblyopia first with glasses and then with patching, if needed.
- Visual acuity in the amblyopic eye between 20/40 and 20/200
- No previous treatment for amblyopia, including glasses or contact lenses
- Amblyopia (lazy eye) in one eye
Respiratory Effects of E-Cigarettes
The purpose of this study is to learn more about how vaping behaviors can affect lung function, symptoms during exercise and activity levels.
You will attend five study visits at OSU (three in the beginning of the study and two after one year). Each visit lasts 1.5 – 4 hours. Study visits will include filling surveys, lung function testing, exercise testing, providing urine samples, and measuring how you vape.
- Current e-cigarette user (daily vaping for at least the past 3 months)
- 21-25 years old
- Normal weight (BMI < 25) or obese (BMI >30)
- Willing to attend 5 study visits to OSU over the course of 1 year
- Willing to abstain from all tobacco and nicotine for at least 12 hours prior to lab sessions
- No lung, heart, thyroid, or neuromuscular problems and no diabetes diagnosis
- Staying within the Columbus/Central Ohio region for the next year
Assessing Responses to Exercise in the Heat in Trained Women
The purpose of this research study is to conduct exercise in hot and neutral environments on women who are aerobically trained and resistance trained to characterize and compare responses across physiologic, perceptual, and neurocognitive domains. Our rationale for this investigation is that its completion would provide evidence as to how women of different fitness backgrounds respond to exercise in the heat and how that response is different from exercising in thermoneutral conditions to better describe how the female body tolerates exercise in the heat with implications for those in recreation, competitive sports, and occupation that expands to emergency and military services.
Aerobically Trained: having a measured aerobic capacity in the 80th percentile according to age
Resistance Trained: able to squat 120% and bench press 60% of their body weight.
Unacclimatized: participants had not been consistently exposed to hot conditions (i.e., sauna, hot yoga, etc.) in the past 2 months.
A Study about Exploring Differences in Attentional Strategies between Autism Spectrum and Neurotypical Individuals in Visual Search Tasks
The purpose of this study is to evaluate if people with autism are different from typical people in the way they pay attention and look for things. They use a special test called the Adaptive Choice Visual Search task to see how people search for things in a picture. In this study, we want to know if people with autism do better or worse than typical people and if they use different strategies to find things. We want to understand why some people with autism are better at paying attention when they look at things.
- Male and females aged 18 to 40 years old
- Normal/corrected vision and color vision
- Autistic participants must be verbal and have an IQ > 70
A Study About the Development of Learning in African-American/Black Children
The purpose of this study is to investigate the early development of attention, learning, and memory during childhood. Participation in this study includes 4, 90-minute-long visits to the lab per year. During these visits, your child will play 2-3 fun, computerized games. These games are designed to assess various aspects of their cognitive ability.
The duration of the study will last 4 years.
Eligibility Criteria:
- African-American/Black children who are 4 years old
An Intervention Study about Primary Care Algorithms for Early Identification of Young Women with von Willebrand Disease
Researchers at Nationwide Children’s Hospital are seeking volunteers to be a part of a study looking at how to best screen for bleeding disorders in young women.
Participants will be asked to undergo a finger prick blood test and complete questionnaires. If their survey answers suggest they have heavy menses, they will also be asked to have a blood draw on the same day.
- Are 10 to 20 years old
- Have had your first menstrual cycle
Cardiovascular Effects of Ketone Ester Ingestion
This study is intended to evaluate the effects of a drink supplement on heart function and health in healthy adults after consuming a ketone ester (KE) supplement drink compared to a placebo drink.
You will undergo an MRI exam for this study. You will also receive six blood draws in total, from an IV catheter set at the beginning of the study.
The duration of this study will comprise a single visit and will last no longer than 4 hours.
Inclusion:
- Able to comply with study requirements as well as pre-test requirements
- BMI between 18 and 30 kg/m2
- Body weight > 150lbs
Exclusion:
Evidence of any physical, mental, and/or medical conditions that would make the proposed studies relatively more hazardous including:
- Pregnancy
- Allergies to components in the test products, including milk protein, and not lactose intolerant
- History of alcoholism (previous 2 years)
- Taking prescriptive medications or over-the-counter (OTC) medications (other than those taken as nutritional supplements for non-therapeutic indications)
- Current smoker
- Contraindications to MRI including cardiac pacemaker or defibrillator, brain aneurysm clips, neuro-stimulator, the presence of any magnetic metal in the body or claustrophobia
Exclusion Criteria varies, please contact Study Coordinator for more information.
A Study to Evaluate E-Cigarette Nicotine Form, Concentration, and Flavor Among Youth
The purpose of this study is to examine the influence of nicotine form, concentration, and e-liquid flavor on youth vaping as well as the heart and lung effects associated with this behavior. You will be asked to attend 9 vaping sessions at The Ohio State University.
Your participation in this study will last up to 6 months.
• Male or females aged 21-25 years old
• Current E-Cigarette user
• Able to attend 9 vaping sessions at The Ohio State University
A Study to Examine Pragmatic Evaluation of Events and Benefits of Lipid-lowering in Older Adults (PREVENTABLE)
The purpose of this study is to evaluate the use of statins to possibly prevent Mild Cognitive Intervention (MCI) or dementia, along with the prevention of physical disability and cardiovascular disease in older adults. Your participation in this study will last up to 5 years.
• Male and females older than 75 years older • No history of heart attack, stroke, revascularization (restore blood flow) or obstructive heart disease where a statin was prescribed • No heart failure hospitalization or statin use within the last 12 months • No history or current evidence of dementia • No condition/situation that would prevent the use of a statin • No major hearing or visual impairment