Official Title Lipid Composition of the Tear Film in Healthy Participants and Dry Eye Disease Patients

Purpose

The purpose of this study is to explore the lipid concentration of the tear film in healthy participants and those who have dry eye disease. 

Could this study be right for you?

Inclusion criteria:

• At least 18 years of age (30 years of age for dry eye disease cohort).
• Good general health (defined by medication use that has not changed within the last month and the absence of medical conditions or treatments that are deemed confounding to the data as determined by the PI)
• Ability to give informed consent
• Willing to spend time for the study; approximately one hour for study assessments
• Either gender

Exclusion criteria:

• Use of any ocular prescription medication (such as but not limited to, glaucoma medications, anti-inflammatory eye drops and Restasis) used within 14 days of the screening visit or started prior to the measurement visit(s).
• Currently having punctal plugs inserted in lacrimal puncta

Inclusion and Exclusion Criteria varies, please contact Study Coordinator for more information. 

Age Range

18 years and up

Official Title Booster Seat Features that Influence Pediatric Posture and Comfort During Extended Time Periods: On-Road Assessment

Purpose

This study will help identify how booster seats influence children’s comfort during car rides and their behaviors. Car seat footrests will also be used to see how children engage with them. Data will be collected during car rides in the caregiver’s personal vehicle. 

Could this study be right for you?

Child is currently riding in a booster seat during travel in the car

Age Range

5 - 12 years

Official Title Project Limb Rescue: A pilot study evaluating the feasibility of transcutaneous sensors for the detection of cancer-related lymphedema.

Purpose

The goal of the study is to test the success of using two types of sensors at rest after a bike exercise on volunteers with and without lymphedema, to look for differences in their readings. This part of the study will be testing persons who do not have lymphedema.

 

Could this study be right for you?

• No history of cancer related to lymphedema, cancer in your arm, or the lymph nodes in the arm
• Able to complete a brief biking exercise for about seven minutes
• No metal implants
• Willingness to take off shoes and any metal jewelry
• Not currently pregnant
• Not currently incarcerated

Your participation will involve completing an online or over the phone screening.

This visit will take approximately 2.5 hours.

Age Range

18 - 90 years

Official Title Strategies to Augment Ketosis: Ketone Conferred Resiliency Against Sleep Restriction (STAK-Sleep)

Purpose

To examine if drinking a ketone supplement, twice a day, can improve brain, digital shooting, and physical performance during short-term sleep restriction (4 nights, 50% of normal sleep).

Could this study be right for you?

• Healthy
• Age: 18 - 40 years old
• BMI: 20-35 kg/m2
• No diagnosed sleep disorders
• Not consuming a ketogenic diet

Age Range

18 - 40 years

Official Title Strategies to Augment Ketosis: Optimization of Ketone Delivery Strategies (STAK: OK'd)

Purpose

This study is intended to evaluate the effects of different dosing measurements for different ketone products in healthy male adults. After giving consent to this study you will schedule 9 testing sessions about 3 days apart. During these sessions you will come into the Physical Activity and Education Services (PAES) building in the morning, having had no food that day and take a study product. Various tests will be administered after ingestion. You will have blood draws to tell us more about your metabolic response to the product.

Could this study be right for you?

• Have a BMI >18 kg/m2 or ≤29 kg/m2
• Do NOT smoke or have diabetes, liver disease, kidney disease, cardiovascular disease, or any form of endocrine dysfunction
• Do NOT currently consume a low carbohydrate diet

Age Range

20 - 30 years

Official Title Understanding the Neurodevelopmental Effects of Youth Tackle Football Participation

Purpose

In this study we are aiming to identify risk factors for higher exposure to football-related neurotrauma in youth tackle football players and to determine the effects of football-related neurotrauma exposure on neurodevelopment in children with no previous tackle football participation.

For this specific posting, we are looking for boys ages 8-12 who are non-athletes or athletes who play non-contact sports to serve as control subjects for our fMRI study. 

Could this study be right for you?

We are looking for boys ages 8-12 who are either non-athletes or do not participate in any contact sports.

• Boys must have no metal implanted in the body
• Have no prior history of head trauma
• Have no serious health or mental health diagnoses
• Must not have a fear of enclosed spaces

Age Range

8 - 12 years

Official Title Exploring the Connectivity and Functional Organization of the Infant Brain

Purpose

The purpose of the study is to investigate how the brain that we are each born with leads to our own unique behavior later in life, and the similarities and differences between maternal and child brains. We are studying infants prenatally and postnatally, following up with them as they grow and develop, and studying their mothers to understand how similar/different they are to their child.

Could this study be right for you?

• Infants under 3 years of age, and pregnant persons who are at least 20 weeks pregnant
• All participants must have no metal implanted in the body
• Have no significant health conditions or history of serious mental illness
• Not suffer from a (fear of enclosed spaces)
• Pregnancies must be without complication.

Age Range

Up to 40 years

Official Title Associations between Race, Gut Microbiota-Metabolites, and Long-Term Symptom Toxicity in African Americans and Caucasian Americans Colorectal Cancer Survivors

Purpose

The purpose of this study is to learn about the associations of symptoms such as fatigue, depression, and gastrointestinal distress including constipation, abdominal pain, and diarrhea with stool microbiomes and metabolites in patients with colorectal cancer. We will compare the associations of symptoms with microbiomes among colorectal cancer patients and healthy patients. You will be asked to complete several surveys that ask questions about your dietary habits, your health history, your social demographics, and your symptoms. You will also be asked to collect a stool sample with an at-home stool sample collection kit that will be provided to you.

Could this study be right for you?

• Diagnosed with stage I-IV colorectal cancer (ICD-10 C18, C19 and C20) OR Healthy.
• 18+ years of age at time of diagnosis.
• Able to communicate in English and provide consent.
• African American OR White.
• Not currently in cancer treatment.
• No current ostomy.
• No chronic bowel disorders (e.g., irritable bowel syndrome).
• No diagnosis of functional GI disorders.
• No food allergies or dietary restrictions.
• No use of probiotics or antibiotics within the past two months prior to fecal collection.
• No significant cognitive or developmental delay that precedes cancer diagnosis (e.g., down syndrome, autism spectrum disorder).

Age Range

18 years and up

Official Title Impulsivity Domains and Subjective Response

Purpose

The purpose of this study is to examine the degree to which different ways of thinking and decision making – measured using computer tasks and questionnaire – relate to how people feel after a dose of alcohol. By doing this study, we hope to learn about the relationships between decision making and responses to alcohol.

Could this study be right for you?

Inclusion criteria include:

1. Ages 21-25
2. Report drinking to an estimated BAC > 80mg% at least once in the past 30 days
3. Report drinking at least twice weekly in the past 30 days
4. English language Fluency

Exclusion criteria include:

1. Any serious medical problems (i.e., liver disease, cardiac abnormality, pancreatitis, diabetes, neurological problems, gastrointestinal disorders, abnormal kidney function)
2. Body weight < 110 or > 210 pounds
3. Current medical or psychiatric condition requiring medication for which alcohol consumption is contraindicated
4. Lifetime history of schizophrenia or other psychotic disorder
5. Substance Use Disorder other than alcohol

Exclusion Criteria varies, please contact Study Coordinator.

Age Range

21 - 25 years

Official Title PRagmatic EValuation of evENTs And Benefits of Lipid-lowering in oldEr adults

Purpose

The purpose of PREVENTABLE is to learn if taking a statin could help older adults live well for longer by preventing dementia, disability, or heart disease. The duration of the study will last 5 years. 

Could this study be right for you?

Inclusion Criteria:

• Community-dwelling adults
• Age ≥75 years
• English or Spanish as primary language

 

Exclusion Criteria:

• Clinically evident cardiovascular disease defined as prior myocardial Infarction (MI), prior stroke, prior revascularization procedure, or a secondary prevention indication for a statin (clinician determined)
• Hospitalization for a primary diagnosis of heart failure in the prior 12 months (Note: History of heart failure in the absence of recent hospitalization or clinically evident cardiovascular disease is not an exclusion)
• Dementia (clinically evident or previously diagnosed)
• Dependence in any Katz Basic Activities of Daily Living [ADL] (with the exception of urinary or bowel continence)
• Severe hearing impairment (preventing phone follow up)
• Unable to talk (preventing phone follow up)

Exclusion Criteria varies, please contact Study Coordinator for more information. 

Age Range

75 years and up