Sleep Restriction and Ketone Supplements

Official Title
Strategies to Augment Ketosis: Ketone Conferred Resiliency Against Sleep Restriction (STAK-Sleep)
Purpose

To examine if drinking a ketone supplement, twice a day, can improve brain, digital shooting, and physical performance during short-term sleep restriction (4 nights, 50% of normal sleep).

Could this study be right for you?
  • Healthy
  • Age: 18 - 40 years old
  • BMI: 20-35 kg/m2
  • No diagnosed sleep disorders
  • Not consuming a ketogenic diet
Age Range
18 - 40 years

Emerging Adulthood and Parenthood Study

Official Title
Emerging Adulthood and Parenthood Study
Purpose

The Emerging Adulthood and Parenthood Study is a qualitative study designed to identify relevant factors and themes related the transitions to adulthood and parenthood in a sample of fathers. We will use qualitative, semi-structured interviews with parents to extract these themes and discuss important aspects about transitioning through life stages. After conducting these interviews, the identified themes will be utilized in the creation of questionnaire to measure the transition to parenthood. The goal of the study is to create a self-report questionnaire measure that captures the domains of emerging adulthood and emerging parenthood.

We are currently looking to recruit fathers for our study. 

Could this study be right for you?
  • Must have at least one biological child
  • Is/was one of the primary non-gestational caregivers (fathers) of that child
  • Speaks English as a first language
Age Range
18 - 65 years

Exogenous Ketone Study

Official Title
Strategies to Augment Ketosis: Optimization of Ketone Delivery Strategies (STAK: OK'd)
Purpose

This study is intended to evaluate the effects of different dosing measurements for different ketone products in healthy male adults. After giving consent to this study you will schedule 9 testing sessions about 3 days apart. During these sessions you will come into the Physical Activity and Education Services (PAES) building in the morning, having had no food that day and take a study product. Various tests will be administered after ingestion. You will have blood draws to tell us more about your metabolic response to the product.

Could this study be right for you?
  • Have a BMI >18 kg/m2 or ≤29 kg/m2
  • Do NOT smoke or have diabetes, liver disease, kidney disease, cardiovascular disease, or any form of endocrine dysfunction
  • Do NOT currently consume a low carbohydrate diet

 

Age Range
20 - 30 years

Neurodevelopmental Effects of Youth Tackle Football

Official Title
Understanding the Neurodevelopmental Effects of Youth Tackle Football Participation
Purpose

In this study we are aiming to identify risk factors for higher exposure to football-related neurotrauma in youth tackle football players and to determine the effects of football-related neurotrauma exposure on neurodevelopment in children with no previous tackle football participation.

For this specific posting, we are looking for boys ages 8-12 who are non-athletes or athletes who play non-contact sports to serve as control subjects for our fMRI study. 

Could this study be right for you?

We are looking for boys ages 8-12 who are either non-athletes or do not participate in any contact sports

  • Boys must have no metal implanted in the body
  • Have no prior history of head trauma
  • Have no serious health or mental health diagnoses
  • Must not have a fear of enclosed spaces
Age Range
8 - 12 years

Exploring the Development of the Infant and Fetal Brain

Official Title
Exploring the Connectivity and Functional Organization of the Infant Brain
Purpose

The purpose of the study is to investigate how the brain that we are each born with leads to our own unique behavior later in life, and the similarities and differences between maternal and child brains. We are studying infants prenatally and postnatally, following up with them as they grow and develop, and studying their mothers to understand how similar/different they are to their child.

Could this study be right for you?
  • Infants under 3 years of age, and pregnant persons who are at least 20 weeks pregnant
  • All participants must have no metal implanted in the body
  • Have no significant health conditions or history of serious mental illness
  • Not suffer froma (fear of enclosed spaces)
  • Pregnancies must be without complication.
Age Range
Up to 40 years

Investigating Symptoms & Stool Gut Bacteria between African Americans and Caucasian Americans

Official Title
Associations between Race, Gut Microbiota-Metabolites, and Long-Term Symptom Toxicity in African Americans and Caucasian Americans Colorectal Cancer Survivors
Purpose

The purpose of this study is to learn about the associations of symptoms such as fatigue, depression, and gastrointestinal distress including constipation, abdominal pain, and diarrhea with stool microbiomes and metabolites in patients with colorectal cancer. We will compare the associations of symptoms with microbiomes among colorectal cancer patients and healthy patients. You will be asked to complete several surveys that ask questions about your dietary habits, your health history, your social demographics, and your symptoms. You will also be asked to collect a stool sample with an at-home stool sample collection kit that will be provided to you.

Could this study be right for you?
  • Diagnosed with stage I-IV colorectal cancer (ICD-10 C18, C19 and C20) OR Healthy.
  • 18+ years of age at time of diagnosis.
  • Able to communicate in English and provide consent.
  • African American OR White.
  • Not currently in cancer treatment.
  • No current ostomy.
  • No chronic bowel disorders (e.g., irritable bowel syndrome).
  • No diagnosis of functional GI disorders.
  • No food allergies or dietary restrictions.
  • No use of probiotics or antibiotics within the past two months prior to fecal collection.
  • No significant cognitive or developmental delay that precedes cancer diagnosis (e.g., down syndrome, autism spectrum disorder).
Age Range
18 years and up

A Study Evaluating How Alcohol Effects Thinking and Decision Making

Official Title
Impulsivity Domains and Subjective Response
Purpose

The purpose of this study is to examine the degree to which different ways of thinking and decision making – measured using computer tasks and questionnaire – relate to how people feel after a dose of alcohol. By doing this study, we hope to learn about the relationships between decision making and responses to alcohol.

Could this study be right for you?

Inclusion criteria include:

  1. Ages 21-25
  2. Report drinking to an estimated BAC > 80mg% at least once in the past 30 days 
  3. Report drinking at least twice weekly in the past 30 days 
  4. English language Fluency

Exclusion criteria include:

  1. Any serious medical problems (i.e., liver disease, cardiac abnormality, pancreatitis, diabetes, neurological problems, gastrointestinal disorders, abnormal kidney function)
  2. Body weight < 110 or > 210 pounds
  3. Current medical or psychiatric condition requiring medication for which alcohol consumption is contraindicated
  4. Lifetime history of schizophrenia or other psychotic disorder
  5. Substance Use Disorder other than alcohol

Exclusion Criteria varies, please contact Study Coordinator. 

Age Range
21 - 25 years

PREVENTABLE

Official Title
PRagmatic EValuation of evENTs And Benefits of Lipid-lowering in oldEr adults
Purpose

The purpose of PREVENTABLE is to learn if taking a statin could help older adults live well for longer by preventing dementia, disability, or heart disease. The duration of the study will last 5 years. 

Could this study be right for you?

Inclusion Criteria:

  • Community-dwelling adults
  • Age ≥75 years
  • English or Spanish as primary language

 

Exclusion Criteria:

  • Clinically evident cardiovascular disease defined as prior myocardial Infarction (MI), prior stroke, prior revascularization procedure, or a secondary prevention indication for a statin (clinician determined)
  • Hospitalization for a primary diagnosis of heart failure in the prior 12 months (Note: History of heart failure in the absence of recent hospitalization or clinically evident cardiovascular disease is not an exclusion)
  • Dementia (clinically evident or previously diagnosed)
  • Dependence in any Katz Basic Activities of Daily Living [ADL] (with the exception of urinary or bowel continence)
  • Severe hearing impairment (preventing phone follow up)
  • Unable to talk (preventing phone follow up)

Exclusion Criteria varies, please contact Study Coordinator for more information. 

Age Range
75 years and up

The Tree of Hope: A Method to Reduce Burnout, Improved Hope and Increase Resilience

Official Title
The Tree of Hope: A Method to Reduce Burnout, Improved Hope and Increase Resilience
Purpose

The purpose of this study is to improve the sense of hope and build resilience through creating one’s Tree of Hope. This study is being done because we see that today’s environment is quite stressful and this can lead to people feeling less hopeful in their present and the future. 

 

Could this study be right for you?
  • At least 18 years old 
  • Able to read and understand English 
  • Healthy people and patients will be eligible for this research study 
  • Participants will be eligible even if they are not seen at OSU for their care.
  • We will not abstract any data from electronic health records. Patients will complete a survey that asks them questions about their health conditions

Exclusion Criteria

  • Any physical or mental condition that the principal investigator considers as impacting the ability of the patient to participate in the research study. Examples include visual or hearing impairment, arthritis, weakness or other medical problem that impairs their ability to write. 
Age Range
18 years and up

Contact Lens Study in Adults with Presbyopia

Official Title
Evaluation of Wear Experience with Dailies TOTAL1 Multifocal® Contact lenses in Presbyopic Adults That Have Dropped out of Contact Lens Wear
Purpose

The purpose of this study is to learn about the wear experience of adults who dropped out of contact lens wear once they became presbyopic. 

Could this study be right for you?
  • Adults who have dropped out of contact lens wear 
  • Ability to attend 3 visits over the course of 5 weeks
  • Satisfy all other study eligibility and exclusion criteria
Age Range
38 years and up