• Evaluation of the Estimated Specificity of the T-SPOT®.TB test for the detection of Tuberculosis infection

    Official Title Evaluation of the Estimated Specificity of the T-SPOT®.TB test for the detection of Tuberculosis infection

    Purpose

    The purpose of this study is to determine the estimated accurateness of the T-SPOT.TB test, with a target of >95% preciseness for the finding of TB infection.

    Your participation will involve completing an online or over the phone screening and a one-time blood sample collection of 10mL (2 teaspoons).  The study visit should take about 30 minutes.

    Could this study be right for you?

    • 18 years of age and older
    • Able to provide Informed Consent
    • Have no symptoms nor suspicion of TB
    • Live in low endemic area for TB
    • Have NO medical record of TB, and not currently or previously diagnosed with TB
    • NOT Pregnant
    • Has NOT been born in or spent three weeks or more cumulatively in any WHO List of high TB burden countries
    • Has NOT spent time, worked in a prison, a homeless shelter or a facility for respiratory healthcare
    • Has NOT been in close contact with someone previously diagnosed with TB
    • Has NOT worked with M. Tuberculosis (Mycobacterium Tuberculosis)

    Your participation will involve completing an online or over the phone screening and a one-time blood sample collection of 10mL (2 teaspoons).

    Age Range

    18 - 90 years
  • Creating Culturally Responsive Early Childhood Programs: Hearing from Parents about what they want

    Official Title An Examination of Culturally Responsive, Inclusive, and Socially Just Practices Parent Feedback

    Purpose

    The research study will examine parents’ - or a child’s primary caregiver - perspectives on an online professional development (PD) training for teachers, targeting early care and education (ECE) teachers’ use of culturally responsive, inclusive, and socially just practices. Parents of young children will be recruited to review the online PD course and complete surveys about the course. A subset of participants will participate in a focus group to share their feedback on the course.

    Could this study be right for you?

    Parent or caregiver to a child who:

    • Is between 3 and 5 years old
    • Is identified as Black/African American
    • Attends a center-based early care and education program (pre-kindergarten, Head Start, child care, preschool, etc.)

    Age Range

    17 - 99 years
  • Hand-eye Coordination Measurements

    Official Title Visuomotor skills assessed with different sports vision-related devices

    Purpose

    The purpose of this project is to determine whether performance correlates between different hand-eye coordination testing and training devices. Two of these devices require the participant to push lighted buttons on a wall-mounted board as fast as possible. The other device requires the participant to push a button at the same time that a (simulated) approaching object arrives.

     

    Could this study be right for you?

    • Visual acuity of 20/20 in each eye
    • Stereoacuity (depth perception) of 60 seconds of arc
    • No eye turn (strabismus) in left, right, or straight ahead gaze

    Age Range

    18 - 40 years
  • An Investigational New Drug for the Treatment of Alzheimer’s Disease

    Official Title A Phase 1, Randomized, Double-Blind, Placebo-Controlled Study Evaluating the Safety, Tolerability, and Pharmacokinetics of Single Escalating Doses of LH-001 in Healthy Subjects

    Purpose

    The purpose of this study is to evaluate the safety and tolerability of an investigational new drug in healthy participants aged 18-60 years.

    Could this study be right for you?

    • In good health and BMI (ratio of body weight to height) between 18-26 kg/m2
    • Willing to participate in various research assessments including blood collection, urine collection, electrocardiogram, and vital signs
    • Willing to stay overnight (~30 hours) in the OSU Hospital Clinical Research Center
    • If sexually active, willing to utilize highly effective birth control during the study period
    • Not currently pregnant or breast-feeding
    • No significant medical condition involving any major organs (heart, lung, liver, brain, or endocrine)
    • No any of the following: cancer, alcohol or substance abuse, spleen problems, or drug hypersensitivity
    • No history of or undergoing treatment for: major psychiatric illness, seizures, or autoimmune disease
    • Not currently taking immunosuppressive drugs
    • No active Hepatitis B, Hepatitis C, or HIV

    Age Range

    18 - 60 years
  • MOMI Study

    Official Title The mom and infant outcomes (MOMI) study: A trial of perinatal outpatient delivery systems

    Purpose

    ​To improve our ability to provide the best possible care to every mom and infant, we are testing two different models of primary care during the first year after childbirth.

    Could this study be right for you?

    • You may qualify if you’re currently pregnant – AND – you’ve ever had high blood pressure, diabetes, depression, or anxiety, including during pregnancy.

    If you participate, you’ll be randomly assigned to an Ohio State location that delivers one of two models of care. Providers at all locations can help you manage your health, but the models differ in several ways.

    • You’ll complete three study visits with surveys, several measurements, and blood and hair sampling. We’ll collect cord blood and review medical records.
  • Provider and Patient Preferences for improving HIV and STI Prevention in Primary Care

    Official Title Client and clinician preferences for same-day PrEP and doxy-PEP awareness, uptake and persistence in primary care.

    Purpose

    The purpose of this study is to better understand the perspectives of both primary care clinicians and the LGBTQ+ clients they serve and how to best improve the awareness and sustained use of available STI and HIV prevention methods to ultimately improve the sexual health disparities among LGBTQ+ populations. 

    Could this study be right for you?

    • 15 years of age or older
    • Speak & read English
    • Identify as LGBTQ+ and have ever used primary care
    • Primary care provider (MD, DO, APRN, PA, PharmD)
    • Have access to the internet

    Age Range

    15 - 150 years
  • One-Year Study of Eye Shape in Young Adult Contact Lens Wearers

    Official Title Longitudinal Changes in Eye Shape in Young Adults Treated with Low-Dose Atropine and Soft Multifocal Contact Lenses

    Purpose

    The purpose of this study is to understand how the myopia control treatments (multifocal contact lenses and low-dose atropine) affect the shape of the eye over one year.

    Could this study be right for you?

    • Nearsighted
    • Current contact lens wearer
    • No significant ocular disease
    • Willingness to be randomized to one of three groups: no intervention, MiSight contact lenses (multifocal contact lenses, instead of current lenses), or daily low-dose atropine eyedrops
    • Willingness to attend a study visit every three months for one year (5 total visits)
    • Meet other study eligibility criteria

    Age Range

    21 - 30 years
  • Contact Lens Study in Adults who Wear Acuvue® Oasys® Contact Lenses

    Official Title Evaluation of Wear Experience with PRECISION7® Contact lenses in habitual Acuvue® Oasys® lens wearers

    Purpose

    The purpose of this study is explorative, evaluating the overall wear experience of individuals who normally wear contact lenses after being refit into each of the two study lenses and wearing them each over 2 weeks.

    Could this study be right for you?

    • Adults who wear Acuvue® Oasys® contact lenses.
    • Ability to attend 3 visits over the course of 4 weeks.
    • Satisfy all other study eligibility and exclusion criteria.

    Age Range

    18 - 40 years
  • Bisexual Health and Relationships Project

    Official Title Bisexual Health and Relationships Project

    Purpose

    The purpose of this study is to better understand the health behaviors and health outcomes for married bisexual people. 

    Could this study be right for you?

    Our study examines the health of married Bi+ (defined as bisexual, pansexual, queer, etc.) people. We are interviewing both Bi+ individuals and their partners over Zoom. We are specifically looking to speak with:

    • Bi+ men married to men
    • Bi+ people of color of any gender

    Age Range

    35 - 65 years
  • Study Evaluating the Tears of the Eye

    Official Title Lipid Composition of the Tear Film in Healthy Participants and Dry Eye Disease Patients

    Purpose

    The purpose of this study is to explore the lipid concentration of the tear film in healthy participants and those who have dry eye disease. 

    Could this study be right for you?

    Inclusion criteria:

    • At least 18 years of age (30 years of age for dry eye disease cohort).
    • Good general health (defined by medication use that has not changed within the last month and the absence of medical conditions or treatments that are deemed confounding to the data as determined by the PI)
    • Ability to give informed consent
    • Willing to spend time for the study; approximately one hour for study assessments
    • Either gender

    Exclusion criteria:

    • Use of any ocular prescription medication (such as but not limited to, glaucoma medications, anti-inflammatory eye drops and Restasis) used within 14 days of the screening visit or started prior to the measurement visit(s).
    • Currently having punctal plugs inserted in lacrimal puncta

    Inclusion and Exclusion Criteria varies, please contact Study Coordinator for more information. 

    Age Range

    18 years and up