Official Title Ontogenesis of Categorization; Linking development, mechanisms, and biology

Purpose

The purpose of this study is to investigate the early development of attention, learning, and memory during childhood. Participation in this study includes 4, 90-minute-long visits to the lab per year. During these visits, your child will play 2-3 fun, computerized games. These games are designed to assess various aspects of their cognitive ability. 

The duration of the study will last 4 years.

Could this study be right for you?

Eligibility Criteria: 

• African-American/Black children who are 4 years old 

Age Range

4 - 4

Official Title An Intervention Study about Primary Care Algorithms for Early Identification of Young Women with von Willebrand Disease

Purpose

Researchers at Nationwide Children’s Hospital are seeking volunteers to be a part of a study looking at how to best screen for bleeding disorders in young women.

Participants will be asked to complete questionnaires. If their survey answers suggest they have heavy menses or abnormal bleeding, they will also be asked to have a blood draw on the same day.

Could this study be right for you?

• Are 9 to 21 years old
• Have had your first menstrual cycle

Age Range

9 - 21

Official Title Microdosed Atropine for the Reduction of Pediatric Myopia Progression (The CHAPERONE Study)

Purpose

The purpose of this study to test the safety and effectiveness of atropine 0.1% and atropine 0.01% eye solutions. These drugs are being tested to see if they slow the worsening of nearsightedness. Children who participate in this study will be asked to use their assigned study medication every night and willing to attend visits at The Ohio State University of Optometry 1 month after starting treatment. These visits will continue for 6 months until the duration of the study ends. This study will take place over a 4-year time period.

Could this study be right for you?

• Children aged 3 to < 13 years old.
• No previous use of medications related to myopia control.
• Glasses and/or contact lens prescription between -1.00 and -6.00 diopters.

Interested guardians who believe their child may be eligible should contact study coordinators to further determine eligibility.

Age Range

3 and up

Official Title Fitness, Aging, Stress & TBI Exposure Repository (FASTER)

Purpose

The purpose of this study is to examine how individual differences in health changes (muscle strength, blood pressure) and behavioral changes (sleep, physical activity) impact memory, attention, and the brain. We study these relationships among a variety of older adults, including those with a history of concussion, traumatic brain injury (TBI), and posttraumatic stress disorder (PTSD). The long-term goal of this project is to identify modifiable factors that exacerbate or protect from age-related cognitive decline.

Could this study be right for you?

Eligibility Criteria:

• Aged 18 years and older
• Speak English
• History of concussion, traumatic brain injury, and/or posttraumatic stress disorder
• Must have primary care physician

Age Range

18 and up

Official Title Radiotracer Imaging of Lower Extremity Skeletal Muscle Perfusion in Patients with Peripheral Arterial Disease

Purpose

The purpose of this study is to study a new method to evaluate blood flow to the calves and feet. We hope this information can help evaluate the effectiveness of treatments and predict clinical outcomes. 

Could this study be right for you?

-Diagnosis of Peripheral Arterial Disease (PAD) OR leg symptoms, such as muscle pain or cramping AND/OR foot wound that has required medical consultation

• Healthy volunteers must:
• Be at least 40 years of age
• Have no history of cardiovascular disease (including high blood pressure)
• Have no history of diabetes mellitus
• Be a non-smoker
• Have normal BMI

Age Range

40 and up

Official Title Mechanisms of Self and Other Evaluation (MeSO Study)

Purpose

The purpose of this study is to better understand the way the brain works in people who have depression and people who have previously been depressed. We are also testing healthy subjects for comparison. We hope our findings will lead to better ways to diagnose and treat mood disorders in the future. Participation involves an initial phone call and a 2 to 4 hour visit to find out if you are eligible. This visit will include completing questionnaires and interviews. If eligible, participants will have a second 3-5 hour visit for an MRI scan. Two months after the scan, participants will complete daily online questionnaires for 7 days. This process is repeated 2 months later (4 months after the scan). 

Could this study be right for you?

You may be eligible for this study if you:

• Are between the ages of 18-40
• Are right-handed
• Do not have a history of neurological disorders (e.g., seizures, head injury, etc.)
• Do not have major medical problems (e.g., stroke, heart disease, high blood pressure, endocrine disorders, etc.)
• Have normal vision, vision that is corrected to normal with glasses or contacts
• Are willing and able to undergo fMRI scanning (not claustrophobic, no non-removable metal in your body)
• Are not pregnant

Age Range

18 and up

Official Title Aggression and Social-Emotional Information Processing: Neural Correlates During Alcohol Intoxication (Columbus Brain Activity Study or CBA)

Purpose

The purpose of this study is to see how alcohol changes brain activity in different groups of study participants who currently drink at least 10 drinks a week and who have (or do not have) “anger issues”. Brain activity will be measured by Magnetic Resonance Imaging (MRI).

Total time you will be in the research study will be for about 4-8 weeks from your initial visit.

Could this study be right for you?

• Healthy men and women 21-55 years of age
• Drink on a regular basis (~ 10 alcoholic beverages per week)
• With a current history of "anger issues" and/or "alcohol issues"
• Able to complete study sessions during the week

Age Range

21 - 55

Official Title Comprehensive Protocol for Cognitive Development Research

Purpose

The purpose of this study is to better understand learning, memory and attention development from childhood to adulthood using eye-tracking techniques.

This study will include one lab visit which will take place on Ohio State's main campus and will last approximately 40-60 minutes.

Could this study be right for you?

Eligibility Criteria:

• Must be 18 and 35 years of age
• Have normal or corrected to normal vision

Age Range

18 and up

Official Title Modeling Cognition and Aging

Purpose

The goal of this study is to develop models to better understand decision-making for young adults, older adults, and adults with early Alzheimer’s disease and Mild Cognitive Impairment. This study involves making simple decisions (such as “are there more blue dots or more yellow dots?”) on a computer. Healthy volunteers will also complete basic tasks such as solving puzzles, questionnaires involving numbers, and will be asked to provide basic demographic and health information.

Could this study be right for you?

You may be eligible for this study if:

• You are ages 18-25 OR
• You are age 60-90 and have NOT been diagnosed with a memory disorder OR
• You are age 60-90 and HAVE been diagnosed with either Mild Cognitive Impairment OR mild Alzheimer's disease
• You are a native English speaker
• You are able to see a computer screen and use hands on keyboard/screen

Age Range

18 and up

Official Title Booster Seats Interview

Purpose

To explore how parents make the decision on transitioning their children from booster seats to seat belts; what factors may influence parents’ decision on the transition.

Could this study be right for you?

Inclusion criteria:

• At least 18 years of age
• A parent or legal guardian who is responsible for transporting their child routinely
• Have a child who stopped using booster seats within 1 year prior to the interview date, and the child who made the transition must be the first child of the parent
• Drive with a child at least once per week
• In good general health
• Fluent in English

Age Range

20 and up