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Metabolism Research Study--Healthy Volunteers Needed
Official Title Adipocyte-T Cell Interactions Modulate Adipose Inflammation and Insulin Sensitivity Following Weight GainPurpose
The purpose of this research study is to better understand the role of fat tissue, how cells in fat tissue communicate, and determine what signals specific cells use to cause inflammation and insulin resistance during weight gain. This may help researchers better understand the process that happens in Type 2 Diabetes. As a result, through the course of six--nine weeks, participants will be asked to gain at least 10% of their starting body weight. A dietitian will meet with participants to give advice to help with meeting the study weight gain goals, as well as provide additional meal vouchers and supplemental shakes as needed. Following the study, participants will receive guidance how to lose the weight they've gained if they would like to do that.
Could this study be right for you?
You may be eligible if you:
- Are 18-60 years of age
- Are lean; Have a BMI 18-24.9 kg/m2 (*see link below for calculating your BMI -- Body Mass Index)
- Have healthy levels of cholesterol and triglycerides (These will be tested at screening)
- Are a non-smoker
- Are non-diabetic
- Are free of chronic illness
- Are not pregnant or breastfeeding
Exclusion Criteria:
- Fasting triglycerides > 150 mg/dL or nonfasting triglycerides ˃ 250 mg/dl
- LDL-Cholesterol level > 150 mg/dL
- Presence of significant anemia (hemoglobin <10.0 gm/dL)
- Currently or planning to take blood thinners
- Current smokers
- Have taken steroids or anti-inflammatory meds for >6 months in the last 6 months
- >10% body weight loss within 3 months of enrollment
- *Other exclusions may apply
Age Range
18 and up -
A Study for Those with Chronic Pancreatitis - The PROCEED Study
Official Title Prospective Evaluation of Chronic Pancreatitis for Epidemiologic and Translational Studies PROCEED Study)Purpose
This study is done for researchers to understand pancreatitis and learn how the disease progresses naturally over time.
From the results of this study, researchers hope to develop some lab tests to support early diagnosis of chronic pancreatitis and to also discover any genetic factors that may affect your chances of developing chronic pancreatitis. The results of this study may also provide information that will open opportunities for new drug discovery.
Could this study be right for you?
- You have a history of acute or chronic pancreatitis OR
- You have experienced pain in your abdomen that a doctor has suggested could be due to pancreatitis
- You are between the ages of 18 and 75
Age Range
18 and up -
Parent-Infant Eye Tracking Study for Children With and Without Hearing Loss
Official Title Development of Parent-Child InteractionsPurpose
This study will examine how a child’s hearing loss may affect the dynamics of parent-child interactions. The study will observe how normal-hearing and hearing-impaired child learn novel words during videotaped parent-child interactions.
Individual study visits may last 30-45 minutes, and there may be multiple study visits per year.
Could this study be right for you?
- Families with children 9 months to 6 years of age
- Children who do and do not have hearing loss may be eligible to participate in this study
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Decision Making Among Couples Concerning "Permanent/Irreversible" Birth Control
Official Title Couple Dynamics Surrounding Contraceptive SterilizationPurpose
This study aims to understand people’s experiences with contraceptive sterilization (such as tubal ligations or vasectomies).
The purpose of this study is to better understand how adults decide to use sterilization as
their main form of birth control. By examining sterilization decisions, this study will
provide a better understanding of how individuals describe and explain their decision
making process.In this study we are interested in learning how people discuss these decisions with their partner, as
well as everyday interactions with their partner, other forms of birth control, and attitudes
about gender more generally.Could this study be right for you?
- Ages 21-55
- Have used tubal ligation or vasectomy as primary contraception, WITHIN the last five (5) years
Participants will be asked to answer a series of questions regarding their experience with sterilization. Interviews will be digitally recorded by audiotape and will remain confidential. The duration of the interview will last approximately one hour to one hour and thirty minutes.
Age Range
21 and up -
A Distracted Driving Study for iPhone and Android Phone Users-- Ages 18 - 20
Official Title Distracted Driving Study--A phone app to reduce cell phone usage among young driversPurpose
This is a study is being done to find out if a phone app reduces calling and texting while driving among young drivers.
Could this study be right for you?
- 18-20 years old
- Use an iPhone or Android smartphone
- Have a full driver’s license that allows unsupervised driving at all times
- Have a car that they are exclusive access to (primary driver, do not share the car)
- Car is insured for liability during crashes
- Driver uses the car more than 2 days a week on average
- Are a US citizen
Age Range
18 and up -
A Study on the Development of COPD
Official Title Extracellular vesicles and the development of COPDPurpose
The study is being done to learn more about how certain smokers develop COPD, chronic obstructive pulmonary disease. By studying microscopic particles (extracellular vesicles) in the blood and lung fluid from smokers we can learn more about this process. This information could lead to better understanding of how smoking damages the lungs and could ultimately help design treatments for people with or at risk for COPD
Could this study be right for you?
- 21 years of age and older
- Current Smoker with at least 10 pack year history
- With or without diagnosis of COPD
- Willing to participate in bronchoscopy procedure
- Not currently diagnosed interstitial lung disease (i.e. sarcoidosis, idiopathic pulmonary fibrosis), lung cancer, primary pulmonary hypertension or have active cardiac disease
Age Range
21 and up -
Media Use and Youth--For Those 12-17 Years of Age
Official Title Media Use and Youth--For Those 12-17 Years of AgePurpose
Researchers want to learn how teens use technology like TV, the internet, video games, and music. The study examines children’s use of media on a daily basis over two weeks.
Your child and one parent will meet with researchers two times on campus. Your child will answer some questions during those meetings. The first meeting will be for about 2 hours and the second meeting will be for about 30 minutes. Over a two week period between those meetings, the child will report daily on activities using a tablet supplied by the study.
Could this study be right for you?
- Ages 12-17 accompanied by one parent or guardian
Age Range
12 and up -
A Study to Better Understand Fainting--The ENCHANT Study--seeking healthy 12-20 year olds
Official Title Electrographic and Neurohormonal Characteristics of Adolescent Nausea during Tilt Table Testing, The ENCHANT StudyPurpose
Researchers are looking for healthy young volunteers in order to understand what happens when someone faints. They want to know about changes in children and teenagers who frequently faint, and compare those who faint to healthy people who do not normally faint.
Researchers want to learn more about what happens to the brain and the stomach when people faint. The electroencephalogram or EEG measures brainwaves. The electrogastrogram or EGG records stomach electrical activity. The goal of this study is to measure how gastric electricity changes during fainting. They will use the EEG to confirm that fainting happened. Researchers will compare results of those who are healthy to patients who faint.
Some individuals with fainting or frequent lightheadedness can have excessive nausea. This is'orthostatic nausea', which means nausea with standing. The purpose of this study is to measure hormones from the blood and electrical changes in the stomach during tilt-table testing in patients and healthy controls. Researchers hope to identify the physiologic changes that lead to orthostatic nausea.
Could this study be right for you?
- Ages 12-20
- No prior fainting or frequent dizziness/lightheadedness
- No prior anxiety or depression
- No medicines that can affect dizziness/lightheadedness
- No difficulties with nausea or abdominal pain
- Normal weight
Age Range
12 and up -
Oral Bacteria Transmission from Mother to Child (Seeking Mothers with Adopted Children)
Official Title Contribution of Genetics to Oral Bacterial Transmission from Mothers to Babies: a Study of Biologic and Adoptive Mother-Child DyadsPurpose
The purpose of this study is to determine how young children get normal mouth bacteria and how it might be passed from mother to child. Researchers want to compare the adoptive mother-child pairs with biologic mother-child pairs to see how closely the bacteria of each set of mothers match those of their children.
Could this study be right for you?
You are eligible for this study if:
- You are a mother with a child who was adopted at birth and is now between the ages of 3 months and 6 years
Age Range
1 and up