Official Title

Extracellular vesicles and the development of COPD

Purpose

The study is being done to learn more about how certain smokers develop COPD, chronic obstructive pulmonary disease. By studying microscopic particles (extracellular vesicles) in the blood and lung fluid from smokers we can learn more about this process. This information could lead to better understanding of how smoking damages the lungs and could ultimately help design treatments for people with or at risk for COPD

Could this study be right for you?

- 21 years of age and older
- Current Smoker with at least 10 pack year history
- With or without diagnosis of COPD
- Willing to participate in bronchoscopy procedure
- Not currently diagnosed interstitial lung disease (i.e. sarcoidosis, idiopathic pulmonary fibrosis), lung cancer, primary pulmonary hypertension or have active cardiac disease

Age Range

21 and up

Official Title

Media Use and Youth--For Those 12-17 Years of Age

Purpose

Researchers want to learn how teens use technology like TV, the internet, video games, and music. The study examines children’s use of media on a daily basis over two weeks.

Your child and one parent will meet with researchers two times on campus. Your child will answer some questions during those meetings. The first meeting will be for about 2 hours and the second meeting will be for about 30 minutes. Over a two week period between those meetings, the child will report daily on activities using a tablet supplied by the study.

Could this study be right for you?

- Ages 12-17 accompanied by one parent or guardian

Age Range

12 and up

Official Title

Electrographic and Neurohormonal Characteristics of Adolescent Nausea during Tilt Table Testing, The ENCHANT Study

Purpose

Researchers are looking for healthy young volunteers in order to understand what happens when someone faints. They want to know about changes in children and teenagers who frequently faint, and compare those who faint to healthy people who do not normally faint.

Researchers want to learn more about what happens to the brain and the stomach when people faint. The electroencephalogram or EEG measures brainwaves. The electrogastrogram or EGG records stomach electrical activity. The goal of this study is to measure how gastric electricity changes during fainting. They will use the EEG to confirm that fainting happened. Researchers will compare results of those who are healthy to patients who faint.

Some individuals with fainting or frequent lightheadedness can have excessive nausea. This is'orthostatic nausea', which means nausea with standing. The purpose of this study is to measure hormones from the blood and electrical changes in the stomach during tilt-table testing in patients and healthy controls. Researchers hope to identify the physiologic changes that lead to orthostatic nausea.

Could this study be right for you?

- Ages 12-20
- No prior fainting or frequent dizziness/lightheadedness
- No prior anxiety or depression
- No medicines that can affect dizziness/lightheadedness
- No difficulties with nausea or abdominal pain
- Normal weight-

Age Range

12 and up

Official Title

Child Attitudes and Behaviors Study

Purpose

The purpose of this study is to examine the effects of parental presence on child task performance (puzzles, drawing, etc.).

Could this study be right for you?

- children between the ages of 8--12 AND his/her parent or guardian

Age Range

8 and up

Official Title

Assessing Reliability and Validity of an iPod App for Measuring Ankle Proprioception

Purpose

We will assess ankle function by measuring how well you detect ankle movement using an iPod app. This information will help us to determine the validity of using an iPod app as a clinical tool for measuring ankle function and perception of rotation

The results of this study may inform us if the iPod app is an appropriate tool to use in the clinical setting as a more cost-effective, faster, and accessible tool when compared to the larger, more expensive Biodex machine.

Could this study be right for you?

Three groups (ages 18-80) are eligible for this study:

--Group 1--Those who are 60-80 years old, without history of ankle instability or nerve damage to lower extremities.

--Group 2--Those who are 18-60 years old and have a history of chronic ankle instability, recurrent ankle sprains. Have had at least 3 ankle sprains in the previous two (2) years, but none within 2 months of joining the study

--Group 3--Those who are 18-60 years old and have been diagnosed with peripheral neuropathy that has been induced by chemotherapy. Further screening will be done by the study team.

Age Range

18 and up

Official Title

Contribution of Genetics to Oral Bacterial Transmission from Mothers to Babies: a Study of Biologic and Adoptive Mother-Child Dyads

Purpose

The purpose of this study is to determine how young children get normal mouth bacteria and how it might be passed from mother to child. Researchers want to compare the adoptive mother-child pairs with biologic mother-child pairs to see how closely the bacteria of each set of mothers match those of their children.

Could this study be right for you?

You are eligible for this study if:
- You are a mother with a child who was adopted at birth and is now between the ages of 3 months and 6 years

Age Range

1 and up