Improving the Breast Cancer Care Delivery Model for Sex and Gender Minority Survivors (LGBTQ+)

Official Title
ImproviNg The BrEast CaNcer Care DelivEry MoDel for Sex and Gender Minority Survivors (INTENDED for SGM)
Purpose

The long-term goal of this study is to improve decision quality and health-related outcomes for sexual gender minority (SGM) breast/chest cancer survivors. The goal is to evaluate important ways the current care model needs adjusted for SGM people, and how best to combine a socially important care model into clinical practice. Survivors: Eligible participants will participate in a 90-minute focus group and online survey regarding your opinions about improving LGBTQ+ breast/chest cancer care. Clinicians: Eligible participants will participate in a 30-minute interview and brief survey regarding your opinions about improving LGBTQ+ breast/chest cancer care. Participation in this study will take no more than 1 hour and 30 minutes.

Could this study be right for you?

Survivors: 1. Self-identify as a member of the SGM community 2. Age ≥18 years at the time of signing the informed consent form 3. Breast/chest cancer survivor in active treatment or completed active treatment in the last 10 years (not including hormone therapy) 5. Be able to read and speak English 6. Have received care in Ohio 7. Be able to participate in virtual meetings Clinicians: 1. Physicians, advance practice providers, nurses, psychologists, social workers, therapists, technologists, and other trained clinical professionals 2. Provide care to individuals diagnosed with breast cancer in Ohio 3. Be able to read and speak English 4. Be able to participate in virtual meetings

Age Range
18 and up

Evaluating a Mobile Health App for Cardio-Oncology Patients

Official Title
Mobile Health App as a Cardiotoxicity Symptom Logging Tool: Feasibility Pilot Study
Purpose

To evaluate the cardio-oncology patient population’s experience with using smart-phone technology as a part of self-management with their care through features such as symptom logging and education. Eligible patients will be asked to participate in a 30-minute virtual interview and/or a 60-minute virtual design or usability session to discuss their thoughts on a mobile app for cardio-oncology patients.

Could this study be right for you?

- English-speaking - Prior cancer diagnosis - Currently undergoing a cancer regimen that includes a targeted, biologic, radiation, and/or immune-based therapy (ex. TKIs and/or ICIs). - No pregnant females - No prisoners

Age Range
18 and up

A Study to Evaluate a Medication Used in Treating Hand-Foot Skin Reaction (HFSR) in Cancer Patients (NOVA-II)

Official Title
A Study to Investigate OQL011 on VEGFR Inhibitor-Associated Hand-Foot Skin Reaction in Cancer Patients (NOVA-II)
Purpose

Hand-Foot Skin Reaction (HFSR) is a common adverse event induced by Vascular Endothelial Growth Receptor Inhibitor (VEGFRi) treatment in cancer patients. The main purpose of this study is to evaluate the safety and efficacy of OQL011 compared to vehicle ointment in treating patients with moderate to severe VEGFRi-associated HFSR. This study will also identify an optimal dosage for Phase III study and explore the pharmacokinetics profile of OQL011 in HFSR patients.

Could this study be right for you?

- Patient must be age 18 years of age or older. - Patient must have a confirmed cancer diagnosis for which VEGFRi treatment is indicated, and must be currently under VEGFRi-based anti-cancer therapy with stable dosage for ≥ 1 week. - Patient on pain medications is allowed provided they have been on stable dosage in the past 1 week and is going to continue at the same dosage.

Age Range
18 and up

A Study of Mobile Health (mHealth), Breast Disease, and Lifestyle Modification

Official Title
Mobile Health (mHealth), Breast Disease, and Lifestyle Modification: Developing a Grounded Theory
Purpose

The purpose of this study is to understand breast cancer survivors use of mobile health (mHealth) apps for lifestyle behavior change - eating a healthier diet, exercising more, dealing with stress, & stopping smoking. Interviews will last approximately 60 - 90 minutes.

Could this study be right for you?

- You have a diagnosis of breast disease or are a breast cancer survivor.
- You are age 18 or older
- You are a female

Age Range
18 and up

Healthy New Albany: Breast Cancer Project

Official Title
Healthy New Albany: Breast Cancer Project
Purpose

Determine the feasibility of delivering a community-based, lifestyle weight management intervention in producing meaningful improvements in weight loss and relevant clinical and patient-reported outcomes in Breast Cancer survivors.

Could this study be right for you?

Female breast cancer survivor within 60 months after cessation of active treatment. Overweight/Obese (BMI > 25). Ability to understand and willing to sign a written informed consent. Willing and physically able to participate in physical activity. Obtain physician consent via primary care physician and/or treating oncologist.

Age Range
30 and up

COMET2 Bronchoscopy: A Study on Filter Ventilation and Product Standard

Official Title
Consortium on Methods Evaluation Tobacco (COMET): Filter Ventilation and Product Standard – COMET2 Bronchoscopy study
Purpose

Smokers (age 21-45) are wanted for an Ohio State University study that provides cigarettes with different filters and that may provide access to other tobacco or nicotine products. Smokers should be willing to undergo two medical procedures called a bronchoscopy.

Could this study be right for you?

- Must be 21 - 45 years of age
- Must be a smoker

Age Range
21 and up

A Study to Assess the Removal of Filter Ventilation on Smoking Behavior and Biomarkers (COMET2)

Official Title
Clinical trial to assess the removal of filter ventilation on smoking behavior and biomarkers (COMET2)
Purpose

Smokers are wanted for an Ohio State University study that provides cigarettes with different filters and that may provide access to other tobacco or nicotine products.

Could this study be right for you?

- You must be a smoker
- At least 21 years of age

Age Range
21 and up

A Study on the Role of Spirituality and Faith during Cancer Treatment

Official Title
Patient perceptions about the role of spirituality and faith during cancer treatment
Purpose

The purpose of the current study is to characterize the perspectives of cancer patients who have undergone a cancer-directed surgery on the role of spirituality and/or religion during their cancer journey in order to better define the desired access to related resources during cancer care. Results from this study will inform future research aimed at addressing patient-centered spirituality/faith needs of cancer patients.

Could this study be right for you?

If you’ve had or will have surgery to treat a cancer diagnosis, you can help researchers at Ohio State examine how patient spirituality and/or religion influences the cancer journey by taking an online survey.

Participants should be:

• Over 18 years old.

• Diagnosed with cancer (all types).

• At least four months past the initial cancer diagnosis.

• Underwent or will receive a surgical procedure related to their cancer

• Able read and write in the English language.

Age Range
18 and up

The impact of E-Cigarette use on the lungs

Official Title
The Effects of a Standardized Research E-Cigarette on the Human Lung
Purpose

This study will look at the effects of electronic cigarette (e-cig) use on the lung (particularly lung inflammation). The study will be of 160 smokers. Some participants will be given a standardized research e-cig (SREC) or nicotine replacement therapy (NRT). The information from this study will help researchers learn if there is any short-term harm to the lung when using e-cigs.

*Samples for the study will taken by two bronchoscopy procedures.

Could this study be right for you?

You may be eligible if you:
- Are 21- 40 years old
- Are a smoker

Age Range
21 and up

Ohio Firefighter Study--Examining the Risk of Occupational Exposure to Smoke

Official Title
Occupational Exposure of Structural Firefighters and Cancer Risk
Purpose

The purpose of this study is to better understand the association between occupational exposure to smoke and risk of cancer. The study is designed to study the exposure of structural firefighters in the State of Ohio to property fire smoke, and determine the link between such exposure and cancer risk. The biological burden (amount in the body - in blood) of environmental contaminants that are long-lived in the body and are emitted in property fire smoke will be used to estimate exposure to be used in the determination of its link with cancer risk: the amounts of this contaminants in the blood will be compared between firefighters in the state that have been diagnosed with cancer and those that have not.

Acute exposure at property fires will also be investigated by measuring environmental contaminants that are emitted in property fire smoke in urine and assessing work and behavioral factors that might contribute to increased exposure. The results of the study are intended to inform the development of effective exposure reduction strategies for structural firefighters.

Could this study be right for you?

You may be eligible for this study if:
- You have been diagnosed with cancer within the previous five (5) years, AND
- You are employed as a structural firefighter in the state of Ohio at the time of diagnosis

Age Range
18 and up