Official Title Sexual and gender diverse young adults' preferences for nicotine and tobacco product attributes

Purpose

We are inviting LGBTQ+ folks to share their opinions about product features (e.g., flavors, nicotine levels) and other factors (e.g., stress, social media, marketing) that make people want to try or continue to use tobacco products.

Could this study be right for you?

• Able to speak English fluently
• Identify as LGBTQ+
• Used nicotine/tobacco products in the past 30-days (cigarettes, cigars, cigarillos, e-cigarettes, etc.)
• Reside in the U.S.

Age Range

18 - 34 years

Official Title Project Limb Rescue: A pilot study evaluating the feasibility of transcutaneous sensors for the detection of cancer-related lymphedema

Purpose

The goal of this study is to use new, adhesive-based sensors (pads that stick on your skin) to detect lymphedema, and to develop a way for patients to check for lymphedema at home.

This study will assist in distinguishing participants with lymphedema in comparison to participants without lymphedema at rest by using a combination of photoplethysmography (PPG) and bioimpedance (BI). Photoplethysmography is an optical technique that can be used to detect blood volume changes in tissue. Bioimpedance evaluates how tissue responds to an externally applied electrical current.

Could this study be right for you?

• History of cancer-related lymphedema, cancer in your arm, or the lymph nodes in the arm
• History of cancer therapy with surgery or radiation involving the axillary basin and upper arm that requires compression or pneumatic therapy
• Physically capable of performing a brief bike riding exercise for about seven minutes
• No metal implants
• Willingness to take off shoes and any metal jewelry
• Not currently pregnant
• Not currently incarcerated

Age Range

18 - 90 years

Official Title Associations between Race, Gut Microbiota-Metabolites, and Long-Term Symptom Toxicity in African Americans and Caucasian Americans Colorectal Cancer Survivors

Purpose

The purpose of this study is to learn about the associations of symptoms such as fatigue, depression, and gastrointestinal distress including constipation, abdominal pain, and diarrhea with stool microbiomes and metabolites in patients with colorectal cancer. We will compare the associations of symptoms with microbiomes among colorectal cancer patients and healthy patients. You will be asked to complete several surveys that ask questions about your dietary habits, your health history, your social demographics, and your symptoms. You will also be asked to collect a stool sample with an at-home stool sample collection kit that will be provided to you.

Could this study be right for you?

• Diagnosed with stage I-IV colorectal cancer (ICD-10 C18, C19 and C20) OR Healthy.
• 18+ years of age at time of diagnosis.
• Able to communicate in English and provide consent.
• African American OR White.
• Not currently in cancer treatment.
• No current ostomy.
• No chronic bowel disorders (e.g., irritable bowel syndrome).
• No diagnosis of functional GI disorders.
• No food allergies or dietary restrictions.
• No use of probiotics or antibiotics within the past two months prior to fecal collection.
• No significant cognitive or developmental delay that precedes cancer diagnosis (e.g., down syndrome, autism spectrum disorder).

Age Range

18 years and up

Official Title Reducing exercise intolerance through inspiratory muscle training in obese breast cancer survivors (IMOCS)

Purpose

The purpose of this study is to better understand why some survivors of breast cancer have difficulty exercising. We also want to learn if breathing exercises can make it easier to tolerate exercise. 

Could this study be right for you?

• Breast Cancer Survivor
• Completed treatment within 6 months–5 years
• Have obesity, defined as body mass index between 30-50 kg/m2
• Can exercise independently

Age Range

18 years and up

Official Title E-PROOF: E-intervention for Protein Intake and Resistance Training to Optimize Function

Purpose

Our team is looking to improve the health of older cancer survivors after they have completed cancer treatment. Specifically, this 12-week study looks to improve older cancer survivors' physical function and related health outcomes (muscle strength, dietary quality, health-related quality of life, self-efficacy, weight management). 

Could this study be right for you?

• History of stage I-III breast, colorectal, and prostate cancer
• Completion of curative treatment (chemotherapy, radiation, surgery)
• Have an email address

Age Range

65 years and up

Official Title The BE FIT Study: Feasibility of an Exercise Intervention on Microbiome and Immune Function
in a High-Risk Cohort for Lung Cancer

Purpose

The purpose of the study is to examine the effects of exercise on long-term smokers in reducing lung cancer risk.

Could this study be right for you?

• Males and females aged 55 to 77 years old
• Current or former smokers with a 20-pack year smoking history (equals 1 pack a day for 20 years, 2 packs a day for 15 years, etc) and smoked within the last 15 years
• Sedentary Lifestyle: fewer than 60 minutes of participation in moderate intensity physical activity each
• Health Status: participants must be free of severe heart, respiratory (e.g. COPD), or systemic disease that would make moderate intensity exercise participation unsafe
• Not currently undergoing cancer treatment
• Not currently taking Immunosuppressants, bisphosphonates, steroids, or probiotics
• No plan to change smoking status

Age Range

55 - 77 years

Official Title Improving emergency care and outcomes of immune-related adverse events: The immune related emergency disposition index (irEDI)

Purpose

The purpose of this study is to learn more about how to best care for patients who have immune-related side effects and have received treatment with an immune checkpoint inhibitor. 

The duration of this study is 30 days. 

Could this study be right for you?

• Must speak English and/or Spanish
• Diagnosis of cancer (excluding non-melanoma skin cancer)
• Last immunotherapy received within 90 days of study enrollment

Age Range

18 years and up

Official Title ImproviNg The BrEast CaNcer Care DelivEry MoDel for Sex and Gender Minority Survivors (INTENDED for SGM)

Purpose

The long-term goal of this study is to improve decision quality and health-related outcomes for sexual gender minority (SGM) breast/chest cancer survivors. The goal is to evaluate important ways the current care model needs adjusted for SGM people, and how best to combine a socially important care model into clinical practice.

Survivors: Eligible participants will participate in a 90-minute focus group and online survey regarding your opinions about improving LGBTQ+ breast/chest cancer care.

Clinicians: Eligible participants will participate in a 30-minute interview and brief survey regarding your opinions about improving LGBTQ+ breast/chest cancer care.

Participation in this study will take no more than 1 hour and 30 minutes.

Could this study be right for you?

Survivors:

1. Self-identify as a member of the SGM community
2. Age ≥18 years at the time of signing the informed consent form
3. Breast/chest cancer survivor in active treatment or completed active treatment in the last 10 years (not including hormone therapy)
4. Be able to read and speak English
5. Have received care in the U.S.
6. Be able to participate in virtual meetings

Clinicians:

1. Physicians, advance practice providers, nurses, psychologists, social workers, therapists, technologists, and other trained clinical professionals
2. Provide care to individuals diagnosed with breast cancer in the U.S.
3. Be able to read and speak English
4. Be able to participate in virtual meetings

Age Range

18 and up

Official Title Mobile Health App as a Cardiotoxicity Symptom Logging Tool: Feasibility Pilot Study

Purpose

To evaluate the cardio-oncology patient population’s experience with using smart-phone technology as a part of self-management with their care through features such as symptom logging and education. Eligible patients will be asked to participate in a 30-minute virtual interview and/or a 60-minute virtual design or usability session to discuss their thoughts on a mobile app for cardio-oncology patients.

Could this study be right for you?

• English-speaking
• Prior cancer diagnosis
• Currently undergoing a cancer regimen that includes a targeted, biologic, radiation, and/or immune-based therapy (e.g., TKIs and/or ICIs).
• No pregnant females
• No prisoners

Age Range

18 and up

Official Title A Study to Investigate OQL011 on VEGFR Inhibitor-Associated Hand-Foot Skin Reaction in Cancer Patients (NOVA-II)

Purpose

Hand-Foot Skin Reaction (HFSR) is a common adverse event induced by Vascular Endothelial Growth Receptor Inhibitor (VEGFRi) treatment in cancer patients. The main purpose of this study is to evaluate the safety and efficacy of OQL011 compared to vehicle ointment in treating patients with moderate to severe VEGFRi-associated HFSR. This study will also identify an optimal dosage for Phase III study and explore the pharmacokinetics profile of OQL011 in HFSR patients.

Could this study be right for you?

• Patient must be age 18 years of age or older.
• Patient must have a confirmed cancer diagnosis for which VEGFRi treatment is indicated, and must be currently under VEGFRi-based anti-cancer therapy with stable dosage for ≥ 1 week.
• Patient on pain medications is allowed provided they have been on stable dosage in the past 1 week and is going to continue at the same dosage.

Age Range

18 and up