• Determining the Best Glasses Prescription for Children with Down Syndrome

    Official Title Dilated Wavefront versus Non-Dilated Wavefront for Metric-Optimized Refraction Procedure for Individuals with Down Syndrome

    Purpose

    The purpose of this study is to examine whether we can use an instrument that measures how the eye focuses light to determine the best glasses prescription.

    Could this study be right for you?

    • Children with Down syndrome age 5 to 17 years
    • Able to do vision tests by naming or matching shapes or letters
    • Able to look at lights for short periods of time
    • No nystagmus (uncontrolled eye movements when trying to look at things)
    • Safe to dilate the eyes - we will screen medical history, eye health, and allergies to determine this
    • No scars on the front of the eye
    • No cataracts
    • No eye diseases like glaucoma or retinal problems

    Age Range

    5 - 17 years
  • A Study about Retirement from Contact Sports after Concussion

    Official Title Retirement from contact sports after concussion

    Purpose

    The purpose of this study is to learn about the experiences of children and young adults after they stop playing contact sports due to concussion.

    Could this study be right for you?

    • Male and females aged 14-22 years old
    • Retired from contact sports due to prior concussion

    Additionally, a parent may participate if their child enrolls. 

    Age Range

    14 - 22 years
  • A Study about Retirement from Contact Sports after Concussion

    Official Title Retirement from Contact Sports after Concussion

    Purpose

    The purpose of this study is to understand the experiences of children and young adults after medical retirement from contact sports due to concussion(s).

    Participants and their parent(s) will complete online questionnaires (about 10 minutes) at the time of enrollment. You will then be scheduled for an interview (about 30 minutes) by video meeting or phone.

    Could this study be right for you?

    • Children and young adults who have retired from contact sports or other high-risk activities (i.e. dirt bike riding, downhill skiing...) due to prior concussion.  
    • Parents may participate if their child enrolls.

    Age Range

    14 - 22 years
  • A Study about Movement Videos to Identify Developmental Abnormalities in Infants

    Official Title The 5000 Baby Project

    Purpose

    The purpose of this study is to develop a screening tool to be used at birth to help lower the age at diagnosis of various developmental disorders. 

    Your infant will lie on their back in their diaper and have a video recorded of their movements. You will be given a medical history questionnaire to fill out during the recording. The visit typically lasts 15-20 minutes.

    Could this study be right for you?

    • Any infants from birth - 6 months (corrected age if applicable) 
    • Parent/legal guardian present and willing to provide informed consent
    • Parent/Legal guardian is English Speaking
  • Ohio Teen Driver Study

    Official Title Leveraging DRVN driver training app to reduce risky driving intentions in novice teen drivers

    Purpose

    The purpose of this study is to see if the bonus safety messages and the amount of app use predicts safe driving attitudes and behaviors at licensure. We are recruiting Ohio teens with learner's permits to use a free driver training app called DRVN. 

    Could this study be right for you?

    • Must have learner's permit to drive in Ohio

    Age Range

    15 - 17
  • A Study about Eye Teaming, Focusing Ability and Quality of Life

    Official Title Development of Patient-Reported Outcome Measures for Children with Concussion-Related and Non-Concussion-Related Non-Strabismic Binocular Vision, Accommodative and Visual Tracking Problems: Phase 1

    Purpose

    The purpose of this study is to assist in development of a new quality of life survey that can be used to learn more about how eye teaming, focusing ability and eye movement problems affect a child’s life.

    Could this study be right for you?

    • Children experiencing eye teaming, focusing, and eye movement problems (with recent concussion or non-concussed)
    • Children with amblyopia (lazy eye) are excluded

    Age Range

    8 - 17 years
  • A Randomized Trial to Evaluate Sequential vs Simultaneous Spectacles plus Patching for Amblyopia in Children 3 to <13 Years Old

    Official Title AMBLYOPIA TREATMENT STUDY (ATS22): A Randomized Trial to Evaluate Sequential vs Simultaneous Spectacles plus Patching for Amblyopia in Children 3 to <13 Years Old

    Purpose

    The purpose of this study is to evaluate if treating amblyopia (lazy eye) with glasses and patching at the same time improves vision as well as treating amblyopia first with glasses and then with patching, if needed.

    Could this study be right for you?

    • Visual acuity in the amblyopic eye between 20/40 and 20/200
    • No previous treatment for amblyopia, including glasses or contact lenses
    • Amblyopia (lazy eye) in one eye

    Age Range

    3 - 12
  • Young Women’s Health Study

    Official Title An Intervention Study about Primary Care Algorithms for Early Identification of Young Women with von Willebrand Disease

    Purpose

    Researchers at Nationwide Children’s Hospital are seeking volunteers to be a part of a study looking at how to best screen for bleeding disorders in young women.

    Participants will be asked to undergo a finger prick blood test and complete questionnaires. If their survey answers suggest they have heavy menses or abnormal bleeding, they will also be asked to have a blood draw on the same day.

    Could this study be right for you?

    • Are 9 to 21 years old
    • Have had your first menstrual cycle

    Age Range

    9 - 21
  • Mentoring to be Active: Peer Mentoring for Rural Appalachian Children to Reduce Overweight and Obesity

    Official Title Mentoring to be Active: Peer Mentoring for Rural Appalachian Children to Reduce Overweight and Obesity

    Purpose

    The purpose of this study is to lower the rate of type 2 diabetes in rural Appalachia youth due to obesity and/or being overweight. Our long-term goal is to improve the health of underserved, high-risk youth.

    This study will test the effectiveness of the Mentored Planning to be Active + Family on physical activity outcomes and health outcomes among rural Appalachian middle school aged youth suffering from either overweight or obesity.

    We have local high school-aged teen mentors work closely with middle school youth to increase social support, self-efficacy, and self-regulation skills to sustain physical activity and improve health before the children enter high school.

    The peer mentoring is followed by a 6-month family reinforcement program.

    Some parents will provide child assessment data of perceived child physical activity behaviors and child health.

     

    Could this study be right for you?

    • Child has access to a computer or tablet device at home for virtual mentoring sessions/meetings
    • Child suffers from overweight or obesity - does not need to be under the care of a health care professional for this condition
    • Child and Parent able to participate read English at a 4th grade level. 
    • Family not expected to move from rural Appalachia within the 18 months. 

    Age Range

    12 - 13
  • A Study to Examine the Early Development of Attention, Learning, and Memory During Childhood

    Official Title A multi-year study of learning during childhood

    Purpose

    The purpose of this study is to investigate the early development of attention, learning, and memory.

    The duration of the study will last over 4 years.

    Participation in this study includes 4, 90-minute-long visits to the lab per year. During these 90-minute-long visits, your child will play 2-3 computerized games, designed to assess different aspects of their cognitive ability.

    Could this study be right for you?

    Children aged 4 years old only; children must be 4 years old at their initial visit to participate.

    Age Range

    4 and up