Study Categories
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A Study about Bordetella Pertussis (Whooping Cough)
Official Title
Identification of novel immunogenic proteins from Bordetella pertussisPurpose
The purpose of this study is to identify new targets to include in a next generation for pertussis (whooping cough). Our goal is to identify new antigens that generate better immune responses against Bordetella pertussis.
You will be in the study for one day when you provide the blood sample.
Could this study be right for you?
- 25-40 years old and do not have diabetes, heart disease, hypertension, auto-immune disease
- Not taking any steroid medications
- Not pregnant
- Know your immunization history
- One time visit
- Healthy Volunteer
Age Range
25 - 40 years -
A Study to Examine the Effects of Exercise in Reducing Lung Cancer Risk in Long-time Smokers
Official Title
The BE FIT Study: Feasibility of an Exercise Intervention on Microbiome and Immune Function
in a High-Risk Cohort for Lung Cancer
Purpose
The purpose of the study is to examine the effects of exercise on long-term smokers in reducing lung cancer risk.
Could this study be right for you?
- Males and females aged 55 to 77 years old
- Current or former smokers with a 20-pack year smoking history (equals 1 pack a day for 20 years, 2 packs a day for 15 years, etc) and smoked within the last 15 years
- Sedentary Lifestyle: fewer than 60 minutes of participation in moderate intensity physical activity each
- Health Status: participants must be free of severe heart, respiratory (e.g. COPD), or systemic disease that would make moderate intensity exercise participation unsafe
- Not currently undergoing cancer treatment
- Not currently taking Immunosuppressants, bisphosphonates, steroids, or probiotics
- No plan to change smoking status
Age Range
55 - 77 years -
Determining the Best Glasses Prescription for Children with Down Syndrome
Official Title
Dilated Wavefront versus Non-Dilated Wavefront for Metric-Optimized Refraction Procedure for Individuals with Down SyndromePurpose
The purpose of this study is to examine whether we can use an instrument that measures how the eye focuses light to determine the best glasses prescription.
Could this study be right for you?
- Children with Down syndrome age 5 to 17 years
- Able to do vision tests by naming or matching shapes or letters
- Able to look at lights for short periods of time
- No nystagmus (uncontrolled eye movements when trying to look at things)
- Safe to dilate the eyes - we will screen medical history, eye health, and allergies to determine this
- No scars on the front of the eye
- No cataracts
- No eye diseases like glaucoma or retinal problems
Age Range
5 - 17 years -
A Study about Short-term and Long-term Impact of COVID-19 on Multiple Sensory Systems
Official Title
Short-term and long-term impact of COVID-19 on multiple sensory systemsPurpose
The purpose of this study is to assess the short-term and long-term impact of COVID-19 on multiple sensory systems, including smell, taste, hearing, and balance.
The study requires about 2.5 hours of your time for your first visit, during which you may undergo smell, taste, hearing, motion, and balance tests. You may be require to participate several follow-up visits, each last 1.5 hours, if you continue to experience symptoms.
Could this study be right for you?
- Adults diagnosed with COVID 19 within the past 1-8 weeks
- Adults with previous COVID-19 diagnosis and has persistent (>90 days) complaints of sensory dysfunctions (smell, taste, chemesthesis, hearing, balance, dizziness)
- Adult with a recent (<8 weeks) upper respiratory infection (cold, flu, etc.)
- Adult with a previous upper respiratory infection (cold, flu, etc.) and has complaints of sensory dysfunctions (smell, taste, hearing, balance, dizziness)
Age Range
18 - 99 years -
A Study about Cancer Survivors’ Preference for Alternative Nicotine-Tobacco Products
Official Title
Collecting information to understand cancer survivors’ preference for alternative nicotine-tobacco productsPurpose
The purpose of this study is to understand how cancer survivors view the risks and benefits of nicotine and tobacco products.
The duration of the study will last two hours.
Could this study be right for you?
- At least 21 years old
- Cancer survivor
- Currently smoking combustible tobacco
- Access to an email address and a phone, tablet, or computer with internet access
- Currently using electronic nicotine delivery systems (e-cigarettes, vape pens, e-hookah, etc.) OR interested in trying them in the future
Age Range
21 years and up -
Sweet Spot Study
Official Title
E-cigarette Nicotine Concentration and Forms: Differential Appeal to Smokers versus Non-smokersPurpose
This study will examine the effect of different e-cigarettes on product appeal.
Could this study be right for you?
- A current e-cigarette user
- 21-24 years old
- Willing to attend a study visit
OR
- A current smoker
- 25-50 years old
- Willing to attend a study visit
- Willing to try e-cigarettes
Age Range
21 - 50 years -
A Study for Patients with Hypereosinophilic Syndrome (HES)
Official Title
A Multicentre, Randomised, Double-blind, Parallel-group, Placebo-controlled, 24-week Phase 3 Study with an Open-label Extension to Evaluate the Efficacy and Safety of Benralizumab in Patients with Hypereosinophilic Syndrome (HES)Purpose
The purpose of this study is to see if benralizumab (biologic drug), given as injections under the skin, can help control your Hypereosinophilic Syndrome (HES) better if it is added to available standard of care HES medications which you may be currently taking.
HES (Hypereosinophilic Syndrome) is a disease characterized by high levels of eosinophils (a particular type of white blood cell) in your blood and a build-up of eosinophils in some organs and tissues (like skin, heart, lungs, intestines or others) causing their dysfunction.
The duration of the study will last 18 months.
Could this study be right for you?
- Eosinophil (a type of white blood cells) count ≥ 1000 cells/μL at screening
- Documented diagnosis of Hypereosinophilic Syndrome (HES)
- History of persistent eosinophilia >1500 cells/μL (at least 2 examinations, interval ≥1 month)
- End organ manifestations attributable to the eosinophilia
Inclusion and Exclusion Criteria varies, please contact Study Coordinator for more information.
Age Range
18 years and up -
A Study about Retirement from Contact Sports after Concussion
Official Title
Retirement from contact sports after concussionPurpose
The purpose of this study is to learn about the experiences of children and young adults after they stop playing contact sports due to concussion.
Could this study be right for you?
- Male and females aged 14-22 years old
- Retired from contact sports due to prior concussion
Additionally, a parent may participate if their child enrolls.
Age Range
14 - 22 years -
A Study about Brain Imaging on Forming Impressions of Food
Official Title
Decoding Social Perceptions in Naturalistic ContextsPurpose
The purpose of this study is to examine impressions on foods. This study involves looking at brain activity while you perform simple tasks (judging images of different foods).
The duration of this study will last 3 hours.
Could this study be right for you?
- Free of MRI contradictions
- No dietary destrictions
- Normal vison
- Right handed
Age Range
18 - 35 years -
A Study about Romantic Relationships
Official Title
Agreement within Romantic RelationshipsPurpose
The purpose of this study is to assess the agreements within romantic relationships on a variety of topics including politics, psychology and the nature of relationships.
Could this study be right for you?
- Must have been in a heterosexual relationship for 3 months
Age Range
18 - 60 years -
Improving Emergency Care and Outcomes of Immune-Related Adverse Events
Official Title
Improving emergency care and outcomes of immune-related adverse events: The immune related emergency disposition index (irEDI)Purpose
The purpose of this study is to learn more about how to best care for patients who have immune-related side effects and have received treatment with an immune checkpoint inhibitor.
The duration of this study is 30 days.
Could this study be right for you?
- Must speak English and/or Spanish
- Diagnosis of cancer (excluding non-melanoma skin cancer)
- Last immunotherapy received within 90 days of study enrollment
Age Range
18 years and up -
A Study for Participants with Type 2 Diabetes Mellitus and Atrial Fibrillation
Official Title
Effect of Glucose Fluctuations on Atrial Fibrillation Burden among Patients with Diabetes Mellitus and Paroxysmal Atrial Fibrillation or Recent Atrial Fibrillation AblationPurpose
The purpose of this study is to examine the effects of glucose levels on atrial fibrillation episodes in people with diabetes and history of atrial fibrillation.
The duration of the study lasts 6 months.
Could this study be right for you?
- Participants diagnosed with type 2 diabetes mellitus
- Body mass index between 25 and 45 kg/m2
- Insulin use at least 10 units per day or more than 1 glucose lowering medication with a hemoglobin A1c greater than 7%
- ICM placement
- Paroxysmal atrial fibrillation (irregular heartbeat that goes back to normal after a week) or atrial fibrillation ablation (procedure to treat irregular heartbeat) within 30 days
Age Range
40 - 79 years