Study Categories

Official Title

Dilated Wavefront versus Non-Dilated Wavefront for Metric-Optimized Refraction Procedure for Individuals with Down Syndrome

Purpose

The purpose of this study is to examine whether we can use an instrument that measures how the eye focuses light to determine the best glasses prescription.

Could this study be right for you?

• Children with Down syndrome age 5 to 17 years
• Able to do vision tests by naming or matching shapes or letters
• Able to look at lights for short periods of time
• No nystagmus (uncontrolled eye movements when trying to look at things)
• Safe to dilate the eyes - we will screen medical history, eye health, and allergies to determine this
• No scars on the front of the eye
• No cataracts
• No eye diseases like glaucoma or retinal problems

Age Range

5 - 17 years

Official Title

Short-term and long-term impact of COVID-19 on multiple sensory systems

Purpose

The purpose of this study is to assess the short-term and long-term impact of COVID-19 on multiple sensory systems, including smell, taste, hearing, and balance.

The study requires about 2.5 hours of your time for your first visit, during which you may undergo smell, taste, hearing, motion, and balance tests. You may be require to participate several follow-up visits, each last 1.5 hours, if you continue to experience symptoms.

 

Could this study be right for you?

• Adults diagnosed with COVID 19 within the past 1-8 weeks
• Adults with previous COVID-19 diagnosis and has persistent (>90 days) complaints of sensory dysfunctions (smell, taste, chemesthesis, hearing, balance, dizziness)
• Adult with a recent (<8 weeks) upper respiratory infection (cold, flu, etc.)
• Adult with a previous upper respiratory infection (cold, flu, etc.) and has complaints of sensory dysfunctions (smell, taste, hearing, balance, dizziness)

Age Range

18 - 99 years

Official Title

E-cigarette Nicotine Concentration and Forms: Differential Appeal to Smokers versus Non-smokers

Purpose

This study will examine the effect of different e-cigarettes on product appeal.

Could this study be right for you?

• A current e-cigarette user
• 21-24 years old
• Willing to attend a study visit

OR

• A current smoker
• 25-50 years old
• Willing to attend a study visit
• Willing to try e-cigarettes

Age Range

21 - 50 years

Official Title

A Multicentre, Randomised, Double-blind, Parallel-group, Placebo-controlled, 24-week Phase 3 Study with an Open-label Extension to Evaluate the Efficacy and Safety of Benralizumab in Patients with Hypereosinophilic Syndrome (HES)

Purpose

The purpose of this study is to see if benralizumab (biologic drug), given as injections under the skin, can help control your Hypereosinophilic Syndrome (HES) better if it is added to available standard of care HES medications which you may be currently taking. 

HES (Hypereosinophilic Syndrome) is a disease characterized by high levels of eosinophils (a particular type of white blood cell) in your blood and a build-up of eosinophils in some organs and tissues (like skin, heart, lungs, intestines or others) causing their dysfunction.

The duration of the study will last 18 months.

Could this study be right for you?

 

• Eosinophil (a type of white blood cells) count ≥ 1000 cells/μL at screening
• Documented diagnosis of Hypereosinophilic Syndrome (HES)
• History of persistent eosinophilia >1500 cells/μL (at least 2 examinations, interval ≥1 month)
• End organ manifestations attributable to the eosinophilia

Inclusion and Exclusion Criteria varies, please contact Study Coordinator for more information.

Age Range

18 years and up

Official Title

Retirement from contact sports after concussion

Purpose

The purpose of this study is to learn about the experiences of children and young adults after they stop playing contact sports due to concussion.

Could this study be right for you?

• Male and females aged 14-22 years old
• Retired from contact sports due to prior concussion

Additionally, a parent may participate if their child enrolls. 

Age Range

14 - 22 years

Official Title

Decoding Social Perceptions in Naturalistic Contexts

Purpose

The purpose of this study is to examine impressions on foods. This study involves looking at brain activity while you perform simple tasks (judging images of different foods). 

The duration of this study will last 3 hours. 

Could this study be right for you?

• Free of MRI contradictions
• No dietary destrictions
• Normal vison
• Right handed

Age Range

18 - 35 years

Official Title

Agreement within Romantic Relationships

Purpose

The purpose of this study is to assess the agreements within romantic relationships on a variety of topics including politics, psychology and the nature of relationships.

Could this study be right for you?

• Must have been in a heterosexual relationship for 3 months

Age Range

18 - 60 years

Official Title

Improving emergency care and outcomes of immune-related adverse events: The immune related emergency disposition index (irEDI)

Purpose

The purpose of this study is to learn more about how to best care for patients who have immune-related side effects and have received treatment with an immune checkpoint inhibitor. 

The duration of this study is 30 days. 

Could this study be right for you?

• Must speak English and/or Spanish
• Diagnosis of cancer (excluding non-melanoma skin cancer)
• Last immunotherapy received within 90 days of study enrollment

Age Range

18 years and up

Official Title

Effect of Glucose Fluctuations on Atrial Fibrillation Burden among Patients with Diabetes Mellitus and Paroxysmal Atrial Fibrillation or Recent Atrial Fibrillation Ablation

Purpose

The purpose of this study is to examine the effects of glucose levels on atrial fibrillation episodes in people with diabetes and history of atrial fibrillation.

The duration of the study lasts 6 months. 

Could this study be right for you?

• Participants diagnosed with type 2 diabetes mellitus
• Body mass index between 25 and 45 kg/m2
• Insulin use at least 10 units per day or more than 1 glucose lowering medication with a hemoglobin A1c greater than 7%
• ICM placement
• Paroxysmal atrial fibrillation (irregular heartbeat that goes back to normal after a week) or atrial fibrillation ablation (procedure to treat irregular heartbeat) within 30 days

Age Range

40 - 79 years

Official Title

BUckeye Concussion Knowledge Survey (BUCKS)

Purpose

The purpose of this study is to examine health outcomes in former Ohio State University athletes who played a varsity sport during their time at OSU. The objective is to determine whether athletes who sustained a concussion have different health outcomes than those who did not sustain a concussion. Any former OSU varsity athlete can participate in a 20-minute online survey.

Could this study be right for you?

• Anyone who has played a varsity sport as an undergraduate student at OSU, and they have now graduated (i.e., OSU athlete alumni). There are no other restrictions in terms of age, sex/gender, type of sport, etc.

Age Range

18 years and up

Official Title

Retirement from Contact Sports after Concussion

Purpose

The purpose of this study is to understand the experiences of children and young adults after medical retirement from contact sports due to concussion(s).

Participants and their parent(s) will complete online questionnaires (about 10 minutes) at the time of enrollment. You will then be scheduled for an interview (about 30 minutes) by video meeting or phone.

Could this study be right for you?

• Children and young adults who have retired from contact sports or other high-risk activities (i.e. dirt bike riding, downhill skiing...) due to prior concussion.  
• Parents may participate if their child enrolls.

Age Range

14 - 22 years

Official Title

A Multicenter, Open-Label Study to Evaluate the Safety, Tolerability, and Effectiveness of CIN-107 for the Management of Blood Pressure in Patients with Primary Aldosteronism

Purpose

The purpose of this study is to see how the study drug CIN-107 works in managing blood pressure in patients with primary aldosteronism (PA), a hormone disorder which causes your body to produce too much of the hormone aldosterone.

The duration of this study is 74 weeks. 

Could this study be right for you?

• Diagnosis of primary aldosteronism (PA)
• Taking an MRA to control BP, such as Spironolactone or Eplerenone, or not yet taking an MRA

Age Range

18 and up