We will include individuals who are:

1) primary, informal, and unpaid caregivers of persons living with dementia,

2) 18 years or older,

3) self-identifying as East Asian Americans (e.g., Chinese, Korean, Japanese, Mongolian, Tibetan, and Taiwanese),

4) immigrants (i.e., first-generation) or children of the first-generation East Asian Americans (i.e., second-generation),

5) fluent in English, and

6) willing to participate.

• 25-40 years old and do not have diabetes, heart disease, hypertension, auto-immune disease
• Not taking any steroid medications
• Not pregnant
• Know your immunization history
• One time visit
• Healthy Volunteer

• Male and females aged 55 to 79 years old
• Current or former smokers with a 20-pack year smoking history (equals 1 pack a day for 20 years, 2 packs a day for 15 years, etc) and smoked within the last 15 years
• Sedentary Lifestyle: fewer than 60 minutes of participation in moderate intensity physical activity each
• Health Status: participants must be free of severe heart, respiratory (e.g. COPD), or systemic disease that would make moderate intensity exercise participation unsafe

• Children with Down syndrome age 5 to 17 years
• Able to do vision tests by naming or matching shapes or letters
• Able to look at lights for short periods of time
• No nystagmus (uncontrolled eye movements when trying to look at things)
• Safe to dilate the eyes - we will screen medical history, eye health, and allergies to determine this
• No scars on the front of the eye
• No cataracts
• No eye diseases like glaucoma or retinal problems

• Adults diagnosed with COVID 19 within the past 1-8 weeks
• Adults with previous COVID-19 diagnosis and has persistent (>90 days) complaints of sensory dysfunctions (smell, taste, chemesthesis, hearing, balance, dizziness)
• Adult with a recent (<8 weeks) upper respiratory infection (cold, flu, etc.)
• Adult with a previous upper respiratory infection (cold, flu, etc.) and has complaints of sensory dysfunctions (smell, taste, hearing, balance, dizziness)

• Aged 18 years or older
• Current undergraduate student at the Ohio State University,
• Willingness to provide informed consent for the research study, and
• Identifies belonging to a racial, ethnic, sexual, or gender minoritized group; or born outside of the U.S.

• At least 21 years old
• Cancer survivor
• Currently smoking combustible tobacco
• Access to an email address and a phone, tablet, or computer with internet access
• Currently using electronic nicotine delivery systems (e-cigarettes, vape pens, e-hookah, etc.) OR interested in trying them in the future

• A current e-cigarette user
• 21-24 years old
• Willing to attend a study visit

OR

• A current smoker
• 25-50 years old
• Willing to attend a study visit
• Willing to try e-cigarettes

• Eosinophil (a type of white blood cells) count ≥ 1000 cells/μL at screening
• Documented diagnosis of Hypereosinophilic Syndrome (HES)
• History of persistent eosinophilia >1500 cells/μL (at least 2 examinations, interval ≥1 month)
• End organ manifestations attributable to the eosinophilia

Inclusion and Exclusion Criteria varies, please contact Study Coordinator for more information.

• Are at least 25 pounds overweight
• Are a non-smoker
• No medications that affect blood sugar, blood pressure, or inflammation

• Male and females aged 14-22 years old
• Retired from contact sports due to prior concussion

Additionally, a parent may participate if their child enrolls. 

• Must currently have presbyopia (unable to focus on objects at near).
• Must have up-to-date pair of progressive-addition glasses (addition power of +1.50 D or higher), worn for at least 2 weeks prior to screening visit.
• Must be a wearer of multifocal contact lenses.
• Meet other study eligibility criteria.