Research studies are looking for volunteers just like you. Both healthy volunteers and participants with specific health conditions are needed to help answer important questions impacting the health of our friends and family. Join us to improve the health of others.

Study Categories

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  • A Study to Evaluate Baricitinib in Adult Patients with Severe or Very Severe Alopecia Areata

    Official Title

    A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Operationally Seamless, Adaptive Phase 2/3 Study to Evaluate the Efficacy and Safety of Baricitinib in Adult Patients with Severe or Very Severe Alopecia Areata BRAVE-AA1

    Purpose

    The purpose of this study is to evaluate the efficacy of baricitinib.

    Could this study be right for you?

    • Subject must self-identify as Black or African American 
    • Subject's current episode of alopecia areata must be more than 6 months and no longer than 8 years
    • Subject must not have any spontaneous improvement 
    • Subject must be in good general health with no history of tuberculosis, heart disease, cancer, HIV, hepatitis B or C, or blood clots 
    • Female subjects must not be pregnant, breastfeeding, or considering becoming pregnant for the duration of the study 

    Age Range

    18 years and up
  • A Study to Evaluate Rocatinlimab in Adults with Atopic Dermatitis (Ezcema)

    Official Title

    A Phase 3, Randomized, 24-week, Placebo-controlled, Double-blind Study to Assess the Efficacy, Safety and Tolerability of Rocatinlimab (AMG 451) Monotherapy in Adult
    Subjects With Moderate-to-severe Atopic Dermatitis (AD) (ROCKET-Horizon)

    Purpose

    The purpose of this study is to evaluate the efficacy of rocatinlimab. 

    Could this study be right for you?

    • Subject must have a diagnosis of atopic dermatitis for a least 6 months prior to study visit
    • Subject must have tried a topical medication with little to no improvement
    • Subject must be in good general health with no history of tuberculosis, heart disease, cancer, HIV, hepatitis B or C, or blood clots 
    • Female subjects must not be pregnant, breastfeeding, or considering becoming pregnant for the duration of the study 

    Age Range

    18 years and up
  • A Study to Evaluate Povorcitinib in Adults with Hidradenitis Suppurativa (HS)

    Official Title

    A Phase 3, Double-Blind, Randomized, Placebo-Controlled, Efficacy and Safety Study of Povorcitinib (INCB054707) in Participants With Moderate to Severe Hidradenitis Suppurativa

    Purpose

    The purpose of this study is to evaluate the efficacy of povorcitinib.

    Could this study be right for you?

    • Subject must have a diagnosis of hidradenitis suppurativa for at least 3 months prior to study visit 
    • Subject must have at least 5 active HS spots in 2 different body areas 
    • Subject must have tried an oral or injected medication for HS with little to no improvement 
    • Subject must be in good general health with no history of tuberculosis, heart disease, cancer, HIV, hepatitis B or C, or blood clots 
    • Female subjects must not be pregnant, breastfeeding, or considering becoming pregnant for the duration of the study 

    Age Range

    18 years and up
  • Impact of A Low Glycemic Index Diet on Blood Pressure and Blood Sugar in Individuals with Spinal Cord Injury

    Official Title

    Two Birds with One Stone: Impact of A Low Glycemic Index Diet on Postprandial Hypotension and Glucose Metabolism in Individuals with Spinal Cord Injury (FIP)

    Purpose

    The purpose of this study is to examine the effect of a short-term low glycemic index diet on blood pressure and blood sugar control after eating.

    Could this study be right for you?

    • Adults aged 18-65 years old
    • Chronic spinal cord injury
    • Level of injury between C4 and L2

    Age Range

    18 - 65 years
  • Brains, Emotion Regulation and Adolescent Moods (BEAM) Study

    Official Title

    Neurodevelopmental Mechanisms Underlying the Onset of Depression among At-Risk Youth: The Role of Dysregulation in the Negative Valence System

    Purpose

    The purpose of this study is to test whether changes in the way in which we react and respond to emotional or stressful information represent a risk factor for depression in kids of mothers with and without depression. Findings from the study have the potential to decrease the high rates of depression observed in children of depressed mothers.  

    Could this study be right for you?

    You may be eligible for this study if:

    • You are 18-65 years old and female.
    • You have a biological child who is between 9 and 14 years of age.
  • Understanding Patient Experiences of Gestational Diabetes

    Official Title

    A Multi-Actor Examination of Gestational Diabetes Mellitus (GDM)

    Purpose

    This study aims to examine the experience of people who have been diagnosed or are currently living with gestational diabetes, including how they manage and make sense of their diagnosis. 

    Could this study be right for you?

    • Aged 18 years or older
    • Must live in the state of Ohio
    • Must be currently pregnant and have been diagnosed with gestational diabetes OR must have been diagnosed with gestational diabetes during a recent pregnancy (within the last 12 months)

    Age Range

    18 years and up
  • A Study for Active Military Service Members (or recently served); Examining Uncertainty, Health, and Home Safety Practices

    Official Title

    Uncertainty and Firearms: Obtaining Secure Storage (UFOS)

    Purpose

    The purpose of this study is to examine whether fear of uncertainty plays a role in home safety practices among firearm owners who are currently or have recently served in the U.S. military.

    Could this study be right for you?

    • Currently serving in any Branch or Component of the U.S. military, or were discharged from the U.S. military within the past 90 days
    • 18 years or older
    • Own at least one firearm located in your home or vehicle
    • Are able to speak and understand the English language
    • Have an Apple or Android smartphone 

    Age Range

    18 - 99 years
  • Research Study on Aging and Health after Cancer

    Official Title

    E-PROOF: E-intervention for Protein Intake and Resistance Training to Optimize Function

    Purpose

    Our team is looking to improve the health of older cancer survivors after they have completed cancer treatment. Specifically, this 12-week study looks to improve older cancer survivors' physical function and related health outcomes (muscle strength, dietary quality, health-related quality of life, self-efficacy, weight management). 

    Could this study be right for you?

    -History of stage I-III breast, colorectal, and prostate cancer

    -Completion of curative treatment (chemotherapy, radiation, surgery)

    -Have an email address

     

    Age Range

    65 years and up
  • Assessing Non-invasive Spinal Stimulation to Evaluate its Safety and Effectiveness in Individuals with Spinal Cord Injury

    Official Title

    ExaStim Upper Limb Pivotal Clinical Validation Study

    Purpose

    The purpose of this study is to evaluate the safety and effectiveness of ExaStim® transcutaneous spinal stimulation on upper extremity function when applied in combination with physical therapy (PT) and/or occupational therapy (OT).

    Participants will be randomized to the stimulation group or a control group. Outcomes will include sensory, motor, and functional tests, as well as questionnaires.

    Could this study be right for you?

    • Aged 22 years or older
    • Traumatic chronic spinal cord injury
    • Level of injury between C2-T2
    • No active implanted medical device for electrical stimulation
    • No Botox for 3 months
    • Have a chronic, traumatic SCI (chronic is >12 months since injury, or 6 months if unchanged symptoms)
    • Has some, but limited upper extremity function
    • BMI <40
    • Cannot be pregnant

     

    Age Range

    22 years and up
  • A study assessing the impact of a treatment on anxiety and stress in individuals with memory concerns.

    Official Title

    Treatment of Stress and Anxiety in mild cognitive impairment (MCI)/Mild Alzheimer's Disease and related dementias (ADRD) and their care partners: A Randomized Controlled Trial

    Purpose

    The purpose of this study is to assess the impact of a treatment on anxiety and stress in individuals with memory concerns and those already with a diagnosis of Mild Cognitive Impairment (MCI), Mild Alzheimer's Disease and related dementias. 

    Could this study be right for you?

    The primary participant must:
    · Be at least 60 years of age
    · Have a “care-partner” that is willing to participate in the full program (such as a spouse, child or a good friend)
    · NOT have a terminal illness or severe motor impairment
    · Be able to use a computer and smartphone and read English at the 6th grade level

    The care partner must:
    · Be at least 18 years of age
    · Be able to use a computer and smartphone and read English at the 6th grade level

    Age Range

    60 - 99 years
  • A Study about Bordetella Pertussis (Whooping Cough)

    Official Title

    Identification of novel immunogenic proteins from Bordetella pertussis

    Purpose

    The purpose of this study is to identify new targets to include in a next generation for pertussis (whooping cough). Our goal is to identify new antigens that generate better immune responses against Bordetella pertussis.

    You will be in the study for one day when you provide the blood sample.

     

    Could this study be right for you?

    • 25-40 years old and do not have diabetes, heart disease, hypertension, auto-immune disease
    • Not taking any steroid medications
    • Not pregnant
    • Know your immunization history
    • One time visit
    • Healthy Volunteer

    Age Range

    25 - 40 years
  • A Study to Examine the Effects of Exercise in Reducing Lung Cancer Risk in Long-time Smokers

    Official Title

    The BE FIT Study: Feasibility of an Exercise Intervention on Microbiome and Immune Function
    in a High-Risk Cohort for Lung Cancer

    Purpose

    The purpose of the study is to examine the effects of exercise on long-term smokers in reducing lung cancer risk.

    Could this study be right for you?

    • Males and females aged 55 to 77 years old
    • Current or former smokers with a 20-pack year smoking history (equals 1 pack a day for 20 years, 2 packs a day for 15 years, etc) and smoked within the last 15 years
    • Sedentary Lifestyle: fewer than 60 minutes of participation in moderate intensity physical activity each
    • Health Status: participants must be free of severe heart, respiratory (e.g. COPD), or systemic disease that would make moderate intensity exercise participation unsafe
    • Not currently undergoing cancer treatment
    • Not currently taking  Immunosuppressants, bisphosphonates, steroids, or probiotics
    • No plan to change smoking status

     

    Age Range

    55 - 77 years