Official Title ExaStim Upper Limb Pivotal Clinical Validation Study

Purpose

The purpose of this study is to evaluate the safety and effectiveness of ExaStim® transcutaneous spinal stimulation on upper extremity function when applied in combination with physical therapy (PT) and/or occupational therapy (OT).

Participants will be randomized to the stimulation group or a control group. Outcomes will include sensory, motor, and functional tests, as well as questionnaires.

Could this study be right for you?

• Aged 22 years or older
• Traumatic chronic spinal cord injury
• Level of injury between C2-T2
• No active implanted medical device for electrical stimulation
• No Botox for 3 months
• Have a chronic, traumatic SCI (chronic is >12 months since injury, or 6 months if unchanged symptoms)
• Has some, but limited upper extremity function
• BMI <40
• Cannot be pregnant

Age Range

22 years and up

Contact Information

Columbus, OH

Raquel Minarsch

raquel.minarsch@osumc.edu

614-293-2812

Official Title Treatment of Stress and Anxiety in mild cognitive impairment (MCI)/Mild Alzheimer's Disease and related dementias (ADRD) and their care partners: A Randomized Controlled Trial

Purpose

The purpose of this study is to assess the impact of a treatment on anxiety and stress in individuals with memory concerns and those already with a diagnosis of Mild Cognitive Impairment (MCI), Mild Alzheimer's Disease and related dementias. 

Could this study be right for you?

The primary participant must:

• Be at least 60 years of age
• Have a “care-partner” that is willing to participate in the full program (such as a spouse, child or a good friend)
• NOT have a terminal illness or severe motor impairment
• Be able to use a computer and smartphone and read English at the 6th grade level

The care partner must:

• Be at least 18 years of age
• Be able to use a computer and smartphone and read English at the 6th grade level

Age Range

60 - 99 years

Contact Information

The Ohio State University, Ohio University, and Florida State University

Sarah Irvin

sarah.irvin@osumc.edu

614-379-3173

Official Title Identification of novel immunogenic proteins from Bordetella pertussis

Purpose

The purpose of this study is to identify new targets to include in a next generation for pertussis (whooping cough). Our goal is to identify new antigens that generate better immune responses against Bordetella pertussis.

You will be in the study for one day when you provide the blood sample.

 

Could this study be right for you?

• 25-40 years old and do not have diabetes, heart disease, hypertension, auto-immune disease
• Not taking any steroid medications
• Not pregnant
• Know your immunization history
• One time visit
• Healthy Volunteer

Age Range

25 - 40 years

Contact Information

OSU Clinical Research Center

Kemba Johnson

kemba.johnson@osumc.edu

614-293-3041

Official Title Short-term and long-term impact of COVID-19 on multiple sensory systems

Purpose

The purpose of this study is to assess the short-term and long-term impact of COVID-19 on multiple sensory systems, including smell, taste, hearing, and balance.

The study requires about 2.5 hours of your time for your first visit, during which you may undergo smell, taste, hearing, motion, and balance tests. You may be require to participate several follow-up visits, each last 1.5 hours, if you continue to experience symptoms.

 

Could this study be right for you?

• Adults diagnosed with COVID 19 within the past 1-8 weeks
• Adults with previous COVID-19 diagnosis and has persistent (>90 days) complaints of sensory dysfunctions (smell, taste, chemesthesis, hearing, balance, dizziness)
• Adult with a recent (<8 weeks) upper respiratory infection (cold, flu, etc.)
• Adult with a previous upper respiratory infection (cold, flu, etc.) and has complaints of sensory dysfunctions (smell, taste, hearing, balance, dizziness)

Age Range

18 - 99 years

Contact Information

Wexner Medical Center Eye and Ear Institute

Ahmad Odeh

odeh03@osumc.edu

614-366-1794

Official Title Retirement from contact sports after concussion

Purpose

The purpose of this study is to learn about the experiences of children and young adults after they stop playing contact sports due to concussion.

Could this study be right for you?

• Male and females aged 14-22 years old
• Retired from contact sports due to prior concussion

Additionally, a parent may participate if their child enrolls.

Age Range

14 - 22 years

Contact Information

Kristen Zellers

kristen.zellers@nationwidechildrens.org

614-355-2791

Official Title BUckeye Concussion Knowledge Survey (BUCKS)

Purpose

The purpose of this study is to examine health outcomes in former Ohio State University athletes who played a varsity sport during their time at OSU. The objective is to determine whether athletes who sustained a concussion have different health outcomes than those who did not sustain a concussion. Any former OSU varsity athlete can participate in a 20-minute online survey.

Could this study be right for you?

• Anyone who has played a varsity sport as an undergraduate student at OSU, and they have now graduated (i.e., OSU athlete alumni). There are no other restrictions in terms of age, sex/gender, type of sport, etc.

Age Range

18 years and up

Contact Information

Stacey Park

park.3367@osu.edu

614-292-3300

Official Title Safety, Tolerability, and Outcomes of Velpatasvir/SofosbuviR in Treatment of Chronic Hepatitis C Virus during Pregnancy (STORC), pregnant woman

Purpose

This study involves evaluating a medication for hepatitis C in pregnant women. 

If you are a pregnant woman with chronic hepatitis C and you join the study, you are consenting to enroll yourself and your baby after he/she is born.

Maternal participants will have 7 visits over approximately 7 months. Infant participants have four visits over approximately the first year of life.

Could this study be right for you?

(This is not a complete list)  

• Must be 18 - 45 years of age
• Chronic HCV infection of at least 6 months
• Singleton pregnancy at 20 + 0 to 30 + 0 weeks’ gestation
• Documented negative Hepatitis B testing for current infection (negative HBsAg test) prior to enrollment
• If living with HIV, must be on antiretroviral therapy

Exclusion Criteria (not a complete list)

• Plans to relocate away from the study site area in the next 16 months and unable/unwilling to return for study visits
• History of cirrhosis
• Known fetal chromosomal abnormality prior to enrollment

Age Range

18 - 45

Contact Information

Melanie Paglione

melanie.paglione@osumc.edu

614-685-5550

Official Title Randomized Trial on Mobile Technology and Young Drivers' Cellphone Use

Purpose

The purpose of this study is to find out if a cell phone app affects driving behavior among young drivers. This information may help us develop public health and traffic safety strategies for young drivers.

 

 

Could this study be right for you?

• 18-24 years old at the time of recruitment
• Must have ownership and exclusive access to a car
• Must have car insurance with at least state-minimum coverage
• Must live in the Greater Columbus Metropolitan Area
• Must drive at least 2 days a week on average
• Must have a functioning iPhone or Android smartphone with an active phone service account (Ex: Verizon, AT&T, etc.)
• Must not have a physical car insurance monitoring device or app installed
• Must speak and read English

Age Range

18 - 24

Contact Information

Maggie Sarle

CellphoneAppDrivingStudy@nationwidechildrens.org

614-507-8990

Official Title Leveraging DRVN driver training app to reduce risky driving intentions in novice teen drivers

Purpose

The purpose of this study is to see if the bonus safety messages and the amount of app use predicts safe driving attitudes and behaviors at licensure. We are recruiting Ohio teens with learner's permits to use a free driver training app called DRVN. 

Could this study be right for you?

• Must have learner's permit to drive in Ohio

Age Range

15 - 17

Contact Information

Ohio

Brittany Shoots-Reinhard

shoots-reinhard.1@osu.edu

6144406258

Official Title Development of Patient-Reported Outcome Measures for Children with Concussion-Related and Non-Concussion-Related Non-Strabismic Binocular Vision, Accommodative and Visual Tracking Problems: Phase 1

Purpose

The purpose of this study is to assist in development of a new quality of life survey that can be used to learn more about how eye teaming, focusing ability and eye movement problems affect a child’s life.

Could this study be right for you?

• Children experiencing eye teaming, focusing, and eye movement problems (with recent concussion or non-concussed)
• Children with amblyopia (lazy eye) are excluded

Age Range

8 - 17 years

Contact Information

Fry Hall, OSU Optometry Clinic

Marjean Kulp

kulp.6@osu.edu

614-688-3336

Official Title AMBLYOPIA TREATMENT STUDY (ATS22): A Randomized Trial to Evaluate Sequential vs Simultaneous Spectacles plus Patching for Amblyopia in Children 3 to <13 Years Old

Purpose

The purpose of this study is to evaluate if treating amblyopia (lazy eye) with glasses and patching at the same time improves vision as well as treating amblyopia first with glasses and then with patching, if needed.

Could this study be right for you?

• Visual acuity in the amblyopic eye between 20/40 and 20/200
• No previous treatment for amblyopia, including glasses or contact lenses
• Amblyopia (lazy eye) in one eye

Age Range

3 - 12

Contact Information

OSU Optometry Clinic and Fry Hall

Marjean Kulp

kulp.6@osu.edu

614-688-3336

Official Title Assessing Responses to Exercise in the Heat in Trained Women

Purpose

The purpose of this research study is to conduct exercise in hot and neutral environments on women who are aerobically trained and resistance trained to characterize and compare responses across physiologic, perceptual, and neurocognitive domains. Our rationale for this investigation is that its completion would provide evidence as to how women of different fitness backgrounds respond to exercise in the heat and how that response is different from exercising in thermoneutral conditions to better describe how the female body tolerates exercise in the heat with implications for those in recreation, competitive sports, and occupation that expands to emergency and military services.

Could this study be right for you?

• Aerobically Trained: having a measured aerobic capacity in the 80th percentile according to age

• Resistance Trained: able to squat 120% and bench press 60% of their body weight.

• Unacclimatized: participants had not been consistently exposed to hot conditions (i.e., sauna, hot yoga, etc.) in the past 2 months.

Age Range

18 - 35

Contact Information

OSU - PAES Building

Barbara Sanchez

sanchez.1094@osu.edu