Research studies are looking for volunteers just like you. Both healthy volunteers and participants with specific health conditions are needed to help answer important questions impacting the health of our friends and family. Join us to improve the health of others.

Study Categories

  • Sleep Restriction and Ketone Supplements

    Official Title
    Strategies to Augment Ketosis: Ketone Conferred Resiliency Against Sleep Restriction (STAK-Sleep)
    Purpose

    To examine if drinking a ketone supplement, twice a day, can improve brain, digital shooting, and physical performance during short-term sleep restriction (4 nights, 50% of normal sleep).

    Could this study be right for you?
    • Healthy
    • Age: 18 - 40 years old
    • BMI: 20-35 kg/m2
    • No diagnosed sleep disorders
    • Not consuming a ketogenic diet
    Age Range
    18 - 40 years
  • Emerging Adulthood and Parenthood Study

    Official Title
    Emerging Adulthood and Parenthood Study
    Purpose

    The Emerging Adulthood and Parenthood Study is a qualitative study designed to identify relevant factors and themes related the transitions to adulthood and parenthood in a sample of fathers. We will use qualitative, semi-structured interviews with parents to extract these themes and discuss important aspects about transitioning through life stages. After conducting these interviews, the identified themes will be utilized in the creation of questionnaire to measure the transition to parenthood. The goal of the study is to create a self-report questionnaire measure that captures the domains of emerging adulthood and emerging parenthood.

    We are currently looking to recruit fathers for our study. 

    Could this study be right for you?
    • Must have at least one biological child
    • Is/was one of the primary non-gestational caregivers (fathers) of that child
    • Speaks English as a first language
    Age Range
    18 - 65 years
  • Exogenous Ketone Study

    Official Title
    Strategies to Augment Ketosis: Optimization of Ketone Delivery Strategies (STAK: OK'd)
    Purpose

    This study is intended to evaluate the effects of different dosing measurements for different ketone products in healthy male adults. After giving consent to this study you will schedule 9 testing sessions about 3 days apart. During these sessions you will come into the Physical Activity and Education Services (PAES) building in the morning, having had no food that day and take a study product. Various tests will be administered after ingestion. You will have blood draws to tell us more about your metabolic response to the product.

    Could this study be right for you?
    • Have a BMI >18 kg/m2 or ≤29 kg/m2
    • Do NOT smoke or have diabetes, liver disease, kidney disease, cardiovascular disease, or any form of endocrine dysfunction
    • Do NOT currently consume a low carbohydrate diet

     

    Age Range
    20 - 30 years
  • A Study Investigating a Medicine to Improve Social Communication in Adolescents and Adults with Autism Spectrum Disorder (ASD).

    Official Title
    MapLight Study (IRIS Clinical Trial)
    Purpose

    The purpose of this study is to investigate a medication intended to improve social communication in adolescents and adults with ASD.

    Could this study be right for you?
    • Have an autism diagnosis or suspect you have an autism diagnosis
    • Have a caregiver or study partner willing to enroll in the study with you
    Age Range
    18 - 45 years
  • A Feasibility Study to Assess the Effect of a Ketogenic Diet as a Co-Therapy for Major Depressive Disorder

    Official Title
    Ketogenic Intervention in Depression (KIND)
    Purpose

    The overarching goal of this pilot study is to: (1) demonstrate that a well-formulated KD can be implemented in treatment program for major depression, and (2) test whether such a program results in reductions of symptoms of depression. 

    Could this study be right for you?

    Inclusion Criteria:

    • OSU students (age 18-30 years at the time of enrollment) with confirmed major depressive disorder as determined by SCID-5 diagnosis at baseline testing.
    • Currently engaged in counseling and or mediation treatment for depression
    • Available for a 12-week period and indicate willingness and ability to eat KD foods as prescribed

    Exclusion Criteria:

    • Disordered eating, as evidenced by meeting criteria for Anorexia Nervosa, Bulimia Nervosa, Binge Eating Disorder, Other Specified Eating Disorder, Unspecified Eating Disorder, or Avoidant Restrictive Eating Disorder during the SCID-5 interview at baseline testing.
    • Substantial imminent risk of suicide as assessed during the SCID-5 interview.
    • Body mass index (BMI) < 20 kg/m2
    • Habitual consumption of a structured low-carbohydrate diet in the last 6-months

    Exclusion Criteria varies, please contact Study Coordinator.

     

    Age Range
    18 - 30 years
  • Pippa Fitness Pessary Device Effectiveness and Safety Study

    Official Title
    Pippa Fitness Pessary Device Effectiveness and Safety Study
    Purpose

    The purpose of this study is to demonstrate the effectiveness and safety of the Pippa Fitness Pessary (device) when self-administered and used in a home environment.
     

    Could this study be right for you?

    . Be a female 18 years or older
    · Live in or near Columbus, Ohio
    · Consistently leak during light exercise
    · Have no prior vaginal surgery

     

    Age Range
    18 years and up
  • Neurodevelopmental Effects of Youth Tackle Football

    Official Title
    Understanding the Neurodevelopmental Effects of Youth Tackle Football Participation
    Purpose

    In this study we are aiming to identify risk factors for higher exposure to football-related neurotrauma in youth tackle football players and to determine the effects of football-related neurotrauma exposure on neurodevelopment in children with no previous tackle football participation.

    For this specific posting, we are looking for boys ages 8-12 who are non-athletes or athletes who play non-contact sports to serve as control subjects for our fMRI study. 

    Could this study be right for you?

    We are looking for boys ages 8-12 who are either non-athletes or do not participate in any contact sports

    • Boys must have no metal implanted in the body
    • Have no prior history of head trauma
    • Have no serious health or mental health diagnoses
    • Must not have a fear of enclosed spaces
    Age Range
    8 - 12 years
  • Exploring the Development of the Infant and Fetal Brain

    Official Title
    Exploring the Connectivity and Functional Organization of the Infant Brain
    Purpose

    The purpose of the study is to investigate how the brain that we are each born with leads to our own unique behavior later in life, and the similarities and differences between maternal and child brains. We are studying infants prenatally and postnatally, following up with them as they grow and develop, and studying their mothers to understand how similar/different they are to their child.

    Could this study be right for you?
    • Infants under 3 years of age, and pregnant persons who are at least 20 weeks pregnant
    • All participants must have no metal implanted in the body
    • Have no significant health conditions or history of serious mental illness
    • Not suffer froma (fear of enclosed spaces)
    • Pregnancies must be without complication.
    Age Range
    Up to 40 years
  • PROMISE

    Official Title
    PRenatal and Obstetric Maternal Exposures and ISlet Autoantibodies in Early Life (PROMISE)
    Purpose

    The purpose of this study is to find out more about how health and exposures during pregnancy, such as having an infection, diet and growth may impact later risk of islet autoimmunity in the
    child. We are also interested in finding out more about why having a father or sibling with type 1 diabetes increases risk of autoimmunity in the child than having a mother with type 1 diabetes.

    Could this study be right for you?

    Inclusion:
    Pregnant women:
    - who is between 8-24 weeks gestation with a singleton pregnancy
    - have had type 1 diabetes for at least 12 months, or the father of the baby or a full sibling of the baby has type 1 diabetes
    - is 18 years of age or older
    - is willing to have blood collected and to complete questionnaires about prenatal exposures once per trimester during their pregnancy (up to 3 visits) and up to 12
    weeks after they deliver their baby
    - is willing to have their baby screened for genetic risk for type 1 diabetes, to complete online questionnaires, and to have their child followed for measurement
    of islet autoimmunity according to the determined risk for type 1 diabetes, through 5-7 years of age.
    o If low risk, two screenings: the first at 2 years of age and the second between 5-7 years of age
    o If high risk, five screenings: every six months through 2 years of age, and one between 5-7 years of age

    The father of the baby will also be asked to complete one visit during pregnancy but it is not mandatory.

    Exclusion:
    - Multiple Gestation pregnancy
    - Mother unable to consent due to intellectual impairment
    - Fetus with known medical issue that would affect study participation
    - Surrogate / gestational mothers who are not biologically related to offspring they are carrying

    Age Range
    18 years and up
  • Investigating Symptoms & Stool Gut Bacteria between African Americans and Caucasian Americans

    Official Title
    Associations between Race, Gut Microbiota-Metabolites, and Long-Term Symptom Toxicity in African Americans and Caucasian Americans Colorectal Cancer Survivors
    Purpose

    The purpose of this study is to learn about the associations of symptoms such as fatigue, depression, and gastrointestinal distress including constipation, abdominal pain, and diarrhea with stool microbiomes and metabolites in patients with colorectal cancer. We will compare the associations of symptoms with microbiomes among colorectal cancer patients and healthy patients. You will be asked to complete several surveys that ask questions about your dietary habits, your health history, your social demographics, and your symptoms. You will also be asked to collect a stool sample with an at-home stool sample collection kit that will be provided to you.

    Could this study be right for you?
    • Diagnosed with stage I-IV colorectal cancer (ICD-10 C18, C19 and C20) OR Healthy.
    • 18+ years of age at time of diagnosis.
    • Able to communicate in English and provide consent.
    • African American OR White.
    • Not currently in cancer treatment.
    • No current ostomy.
    • No chronic bowel disorders (e.g., irritable bowel syndrome).
    • No diagnosis of functional GI disorders.
    • No food allergies or dietary restrictions.
    • No use of probiotics or antibiotics within the past two months prior to fecal collection.
    • No significant cognitive or developmental delay that precedes cancer diagnosis (e.g., down syndrome, autism spectrum disorder).
    Age Range
    18 years and up
  • Research Study on Light Sensitivity after Head Injury

    Official Title
    Effect of Fixation Training with Colored Light Targets on Traumatic Brain Injury-Associated Photophobia
    Purpose

    Researchers at The Ohio State University College of Optometry are seeking individuals with a recent history of head trauma who are experiencing light sensitivity. The goal of this study is to determine if daily 20 minute fixation training sessions using a colored (red or blue) light target affects symptoms of light sensitivity, or alters other measurements of the eyes and vision including pupil response.  

    This study will involve attending five 1-2 hour study visits, occurring every 1.5 months for 6 months. Study visits will include answering questions about eye and health history, completing surveys, reading letters on an eye chart, having the pupils measured in response to flashes of light, measuring the side vision, measuring eye alignment and in some cases focusing ability. Outside of the study visits, participants will also complete daily 20 minute fixation training sessions for 6 months using a colored (red or blue) light target, completed at home between study visits.

    Could this study be right for you?
    • Must be 18 to 80 years old
    • Experienced a head injury 3 or more months ago
    • Current symptoms of light sensitivity
    • Be healthy and have good eye health 
    Age Range
    18 - 80 years
  • A Study Evaluating How Alcohol Effects Thinking and Decision Making

    Official Title
    Impulsivity Domains and Subjective Response
    Purpose

    The purpose of this study is to examine the degree to which different ways of thinking and decision making – measured using computer tasks and questionnaire – relate to how people feel after a dose of alcohol. By doing this study, we hope to learn about the relationships between decision making and responses to alcohol.

    Could this study be right for you?

    Inclusion criteria include:

    1. Ages 21-25
    2. Report drinking to an estimated BAC > 80mg% at least once in the past 30 days 
    3. Report drinking at least twice weekly in the past 30 days 
    4. English language Fluency

    Exclusion criteria include:

    1. Any serious medical problems (i.e., liver disease, cardiac abnormality, pancreatitis, diabetes, neurological problems, gastrointestinal disorders, abnormal kidney function)
    2. Body weight < 110 or > 210 pounds
    3. Current medical or psychiatric condition requiring medication for which alcohol consumption is contraindicated
    4. Lifetime history of schizophrenia or other psychotic disorder
    5. Substance Use Disorder other than alcohol

    Exclusion Criteria varies, please contact Study Coordinator. 

    Age Range
    21 - 25 years