Search Studies

Official Title E-PROOF: E-intervention for Protein Intake and Resistance Training to Optimize Function

Purpose

Our team is looking to improve the health of older cancer survivors after they have completed cancer treatment. Specifically, this 12-week study looks to improve older cancer survivors' physical function and related health outcomes (muscle strength, dietary quality, health-related quality of life, self-efficacy, weight management). 

Could this study be right for you?

-History of stage I-III breast, colorectal, and prostate cancer

-Completion of curative treatment (chemotherapy, radiation, surgery)

-Have an email address

 

Age Range

65 years and up

Official Title ExaStim Upper Limb Pivotal Clinical Validation Study

Purpose

The purpose of this study is to evaluate the safety and effectiveness of ExaStim® transcutaneous spinal stimulation on upper extremity function when applied in combination with physical therapy (PT) and/or occupational therapy (OT).

Participants will be randomized to the stimulation group or a control group. Outcomes will include sensory, motor, and functional tests, as well as questionnaires.

Could this study be right for you?

• Aged 22 years or older
• Traumatic chronic spinal cord injury
• Level of injury between C2-T2
• No active implanted medical device for electrical stimulation
• No Botox for 3 months
• Have a chronic, traumatic SCI (chronic is >12 months since injury, or 6 months if unchanged symptoms)
• Has some, but limited upper extremity function
• BMI <40
• Cannot be pregnant

 

Age Range

22 years and up

Official Title Treatment of Stress and Anxiety in mild cognitive impairment (MCI)/Mild Alzheimer's Disease and related dementias (ADRD) and their care partners: A Randomized Controlled Trial

Purpose

The purpose of this study is to assess the impact of a treatment on anxiety and stress in individuals with memory concerns and those already with a diagnosis of Mild Cognitive Impairment (MCI), Mild Alzheimer's Disease and related dementias. 

Could this study be right for you?

The primary participant must:
· Be at least 60 years of age
· Have a “care-partner” that is willing to participate in the full program (such as a spouse, child or a good friend)
· NOT have a terminal illness or severe motor impairment
· Be able to use a computer and smartphone and read English at the 6th grade level

The care partner must:
· Be at least 18 years of age
· Be able to use a computer and smartphone and read English at the 6th grade level

Age Range

60 - 99 years

Official Title Identification of novel immunogenic proteins from Bordetella pertussis

Purpose

The purpose of this study is to identify new targets to include in a next generation for pertussis (whooping cough). Our goal is to identify new antigens that generate better immune responses against Bordetella pertussis.

You will be in the study for one day when you provide the blood sample.

 

Could this study be right for you?

• 25-40 years old and do not have diabetes, heart disease, hypertension, auto-immune disease
• Not taking any steroid medications
• Not pregnant
• Know your immunization history
• One time visit
• Healthy Volunteer

Age Range

25 - 40 years

Official Title The BE FIT Study: Feasibility of an Exercise Intervention on Microbiome and Immune Function
in a High-Risk Cohort for Lung Cancer

Purpose

The purpose of the study is to examine the effects of exercise on long-term smokers in reducing lung cancer risk.

Could this study be right for you?

• Males and females aged 55 to 77 years old
• Current or former smokers with a 20-pack year smoking history (equals 1 pack a day for 20 years, 2 packs a day for 15 years, etc) and smoked within the last 15 years
• Sedentary Lifestyle: fewer than 60 minutes of participation in moderate intensity physical activity each
• Health Status: participants must be free of severe heart, respiratory (e.g. COPD), or systemic disease that would make moderate intensity exercise participation unsafe
• Not currently undergoing cancer treatment
• Not currently taking  Immunosuppressants, bisphosphonates, steroids, or probiotics
• No plan to change smoking status

 

Age Range

55 - 77 years

Official Title Dilated Wavefront versus Non-Dilated Wavefront for Metric-Optimized Refraction Procedure for Individuals with Down Syndrome

Purpose

The purpose of this study is to examine whether we can use an instrument that measures how the eye focuses light to determine the best glasses prescription.

Could this study be right for you?

• Children with Down syndrome age 5 to 17 years
• Able to do vision tests by naming or matching shapes or letters
• Able to look at lights for short periods of time
• No nystagmus (uncontrolled eye movements when trying to look at things)
• Safe to dilate the eyes - we will screen medical history, eye health, and allergies to determine this
• No scars on the front of the eye
• No cataracts
• No eye diseases like glaucoma or retinal problems

Age Range

5 - 17 years

Official Title Short-term and long-term impact of COVID-19 on multiple sensory systems

Purpose

The purpose of this study is to assess the short-term and long-term impact of COVID-19 on multiple sensory systems, including smell, taste, hearing, and balance.

The study requires about 2.5 hours of your time for your first visit, during which you may undergo smell, taste, hearing, motion, and balance tests. You may be require to participate several follow-up visits, each last 1.5 hours, if you continue to experience symptoms.

 

Could this study be right for you?

• Adults diagnosed with COVID 19 within the past 1-8 weeks
• Adults with previous COVID-19 diagnosis and has persistent (>90 days) complaints of sensory dysfunctions (smell, taste, chemesthesis, hearing, balance, dizziness)
• Adult with a recent (<8 weeks) upper respiratory infection (cold, flu, etc.)
• Adult with a previous upper respiratory infection (cold, flu, etc.) and has complaints of sensory dysfunctions (smell, taste, hearing, balance, dizziness)

Age Range

18 - 99 years

Official Title A Multicentre, Randomised, Double-blind, Parallel-group, Placebo-controlled, 24-week Phase 3 Study with an Open-label Extension to Evaluate the Efficacy and Safety of Benralizumab in Patients with Hypereosinophilic Syndrome (HES)

Purpose

The purpose of this study is to see if benralizumab (biologic drug), given as injections under the skin, can help control your Hypereosinophilic Syndrome (HES) better if it is added to available standard of care HES medications which you may be currently taking. 

HES (Hypereosinophilic Syndrome) is a disease characterized by high levels of eosinophils (a particular type of white blood cell) in your blood and a build-up of eosinophils in some organs and tissues (like skin, heart, lungs, intestines or others) causing their dysfunction.

The duration of the study will last 18 months.

Could this study be right for you?

 

• Eosinophil (a type of white blood cells) count ≥ 1000 cells/μL at screening
• Documented diagnosis of Hypereosinophilic Syndrome (HES)
• History of persistent eosinophilia >1500 cells/μL (at least 2 examinations, interval ≥1 month)
• End organ manifestations attributable to the eosinophilia

Inclusion and Exclusion Criteria varies, please contact Study Coordinator for more information.

Age Range

18 years and up

Official Title Retirement from contact sports after concussion

Purpose

The purpose of this study is to learn about the experiences of children and young adults after they stop playing contact sports due to concussion.

Could this study be right for you?

• Male and females aged 14-22 years old
• Retired from contact sports due to prior concussion

Additionally, a parent may participate if their child enrolls. 

Age Range

14 - 22 years

Official Title Improving emergency care and outcomes of immune-related adverse events: The immune related emergency disposition index (irEDI)

Purpose

The purpose of this study is to learn more about how to best care for patients who have immune-related side effects and have received treatment with an immune checkpoint inhibitor. 

The duration of this study is 30 days. 

Could this study be right for you?

• Must speak English and/or Spanish
• Diagnosis of cancer (excluding non-melanoma skin cancer)
• Last immunotherapy received within 90 days of study enrollment

Age Range

18 years and up

Official Title BUckeye Concussion Knowledge Survey (BUCKS)

Purpose

The purpose of this study is to examine health outcomes in former Ohio State University athletes who played a varsity sport during their time at OSU. The objective is to determine whether athletes who sustained a concussion have different health outcomes than those who did not sustain a concussion. Any former OSU varsity athlete can participate in a 20-minute online survey.

Could this study be right for you?

• Anyone who has played a varsity sport as an undergraduate student at OSU, and they have now graduated (i.e., OSU athlete alumni). There are no other restrictions in terms of age, sex/gender, type of sport, etc.

Age Range

18 years and up

Official Title Retirement from Contact Sports after Concussion

Purpose

The purpose of this study is to understand the experiences of children and young adults after medical retirement from contact sports due to concussion(s).

Participants and their parent(s) will complete online questionnaires (about 10 minutes) at the time of enrollment. You will then be scheduled for an interview (about 30 minutes) by video meeting or phone.

Could this study be right for you?

• Children and young adults who have retired from contact sports or other high-risk activities (i.e. dirt bike riding, downhill skiing...) due to prior concussion.  
• Parents may participate if their child enrolls.

Age Range

14 - 22 years