Search Studies
Research studies are looking for volunteers just like you. Both healthy volunteers and participants with specific health conditions are needed to help answer important questions impacting the health of our friends and family. Join us to improve the health of others.
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Kicking the Habit: A Research Study Testing the Buckeye Quit Stick
Official Title A Pilot/Feasibility Study of the Buckeye Quit Stick: A Novel Resource for Successful Tobacco CessationPurpose
The Buckeye Quit Stick is part of a research study to learn whether people are willing to use a handheld stick as a tool for the hand-mouth routine of smoking. It focuses on the hand-to-mouth habit by providing something to hold and use instead of a cigarette. The main goal of this study is to see if patients that plan to quit smoking will use this device and evaluate their experiences with the Buckeye Quit Stick.
Participants will also continue to receive national guidelines for smoking cessation support from the James Comprehensive Cancer Center Smoking Cessation Clinic. A participant is considered to have completed the research study when they complete all study visits or at approximately 6 months.Could this study be right for you?
- Must be 21 years of age or older
- Patient of the OSU clinics
- Current self-reported smoker
Age Range
21 years and up -
Emotions, Stress, and Mental Health
Official Title Emotions and Stress StudyPurpose
We are conducting a study to learn about the ways that adults cope with different types of stress in daily life. If you choose to participate in this study, you will be asked to answer a few questions to determine if you are a good fit for the study.
If you are a good fit for the study, you will attend a virtual meeting with a researcher, complete 2 questionnaires about your emotions and coping strategies, and complete short surveys multiple times per day for one week. This virtual meeting and first questionnaire will take about 1 hour to complete. The short surveys will take about 2-5 minutes to complete. The last questionnaire will take about 30 minutes to complete. The final questionnaire will take no longer than an hour to complete.
This entire study will last up to 5.5 hours total.
Could this study be right for you?
Individuals who identify as Black or African American.
Age Range
18 years and up -
Contact Lens Performance during Long Days of Wear
Official Title Evaluation of Wear Experience with Dailies Total 1® for Astigmatism Contact Lenses on Long Lens-Wear DaysPurpose
For this study, we are investigating the performance of a daily disposable lens in individuals who have astigmatism and are willing to wear contacts for the majority of their day (~16 hours a day).
Could this study be right for you?
Eligibility:
- Adults ages 18-40 years old.
- Willing to wear soft, single vision contact lenses during long days (approximately 16 hours/day).
- Access to a smart device and willingness to complete surveys throughout the day on the survey days.
Age Range
18 - 40 years -
Preserving Manual Wheelchair User Shoulder Health
Official Title Quantifying Musculoskeletal Adaptations to Manual Wheelchair Use Across the LifespanPurpose
Manual wheelchair use places high physical demands on the arms and shoulders, which can lead to pain and injury, especially with aging. This study aims to understand how wheelchair use affects shoulder anatomy and movement to improve prevention, early detection, and treatment of upper extremity pain and injury in manual wheelchair users.
Participation includes two in-person research sessions, each lasting about 60 minutes, conducted at the Martha Morehouse Medical Pavilion:
- MRI session to examine shoulder anatomy (no radiation involved)
- Movement analysis session to assess muscle activity and arm function during everyday tasks such as wheelchair propulsion and reaching
Sessions may be completed on the same day or on different days within one week.
Total study participation is approximately 2 hours.
Could this study be right for you?
- Adults (>18 years old) who are primary manual wheelchair users
- Must be able to safely participate in MRI and movement analysis
- Individuals who are pregnant or have MRI-incompatible metal implants are not eligible
Age Range
18 - 110 years -
Chill Nic (Nicotine Pouch) Study
Official Title Examining the Role of Cooling Agents in Oral Nicotine PouchesPurpose
Adult cigarette smokers who live in Ohio are invited to participate in 5 study visits to understand how different nicotine pouches compare to one another as well as their usual brand of cigarette. Each visit lasts about 1 hour.
Participation involves visiting our lab, trying oral nicotine pouches, smoking your regular brand of cigarette, and filling out surveys.
Could this study be right for you?
- Must be a current cigarette user
- Must be 21 years old or older
- Must be willing to attend 5 study visits at OSU
Age Range
21 years and up -
How Do Ketone Supplements Affect Brain Function in Healthy Adults
Official Title Effects of Acute Ketone Supplementation on the Brain (KETO-BRAIN)Purpose
This study looks at how ketone drinks affect the brain in healthy adults. Ketones are natural substances your body makes when it breaks down fat for energy. Scientists think ketones might help protect the brain and improve how it works.
We want to learn if drinking a ketone supplement changes blood flow to the brain and affects brain chemicals that help with thinking and memory. This information could help us understand if ketone drinks might be helpful for brain health as people age.
If you join this study, you will:
- Come to the research center 3 times over about 1-2 weeks
- Drink either a ketone supplement or a comparison drink (you will not know which one)
- Have brain scans using an MRI machine (like a large medical camera)
- Take simple thinking tests on a computer
- Have finger stick blood tests to measure ketone and sugar levels
You will first come in for a consent visit that take about 1 hour. Then, you will return for two more visits that will take about 3 hours each. You will drink a special beverage twice a day for two days before each scan visit. The study uses MRI scans to safely take pictures of your brain without radiation. We will measure blood flow in your brain and certain brain chemicals before and after you drink the supplement.
This research may help scientists better understand how ketones work in the brain. This could lead to new ways to support brain health in the future.
Could this study be right for you?
Who Can Join:
- Body Mass Index (BMI) between 18.5 and 30
- Able to skip eating overnight before study visits
- Not following a keto diet
Who Cannot Join:
- People who do not speak English
- Currently using ketone supplements or following a keto diet
- Pregnant or breastfeeding
- Allergic to milk protein or lactose intolerant
- History of high blood pressure
- History of alcohol problems in the past 2 years
- History of illegal drug use
- Head injury that caused loss of consciousness
- Brain or nerve disease diagnosis
- Taking medications for mental health conditions
- Current smokers
- Anyone with metal in their body or other reasons they cannot have an MRI scan
Age Range
45 - 65 years -
Behavioral Assessment Method Index (BAM)
Official Title Behavioral Assessment Method Index (BAM)Purpose
The goal of this study is to develop measurements that can improve treatments for children who suffered a stroke. When young infants suffer a stroke, they often have long-term difficulties in the use of their arms and hands. Learning more about the development of reach-and grasps behaviors in healthy, typically developing children will help us develop better treatments for impaired children.
You and your child will visit our lab four times: at the beginning of the study, and one, three and 7 months after the beginning of the study. A trained assessor administers game-like activities to your child. Each assessment involves direct evaluation of the child’s development in fine motor, gross motor, language, and cognitive development and will take about 2 hours.
Could this study be right for you?
Inclusion:
Age: Between 8 and 36 months old at baseline
Full Term Birth (37 to 41 weeks gestation)
Healthy development (meeting milestones)
Exclusion:
Diagnosed or suspected impairments (auditory, visual, cognitive, motor)
Age Range
4 - 36 months -
Participate in an Eight-week Online Mind-body Research Intervention for Brain Health
Official Title Internet-based Mind-Body Training (iMBT) for Brain HealthPurpose
The Clinical Neuroscience Laboratory is looking for male volunteers (ages 50 years and older) with cognitive concerns to participate in an online eight-week mind-body research intervention for promoting brain health.
Participation will involve web-based, phone-based, and in-person assessment sessions. Assessment sessions will include a blood draw, neuropsychological assessments, MRI scan, and Fitbit tracking followed by the eight-week online internet-based mind-body intervention where participants are invited to complete one 2.5 hour session per week at their own pace.
Could this study be right for you?
- At least 50 years old and concerned about your memory or attention?
- Fluent in English?
- Do you have access to WiFi at home?
- Never diagnosed with mild cognitive impairment or dementia?
- Live in the Greater Columbus Metropolitan area?
- Willing to commit to a virtual research intervention and in-person assessments?
Age Range
50 years and up -
Child Screen Time and Eye Health Survey
Official Title Child Screen Time and Eye Health SurveyPurpose
The purpose of the study is to assess the relationship between hours of screen time and dry eye symptoms in children.
You will be required to take one online survey, which takes about 5 minutes to complete.
Could this study be right for you?
- Parents or legal guardians of children.
Age Range
Up to 18 years -
CP-MOVES: Standing Intervention for Children with Motor Delays.
Official Title CP-MOVES: Complex rehabilitation technology enabled Physical activity for children with Motor delays Via telehealth in natural EnvironmentsPurpose
This study will examine physical activity, sleep, and quality of life in children with severe motor delays and their parents before and after an 8-week intervention using adaptive standers.
Parents with a child with severe motor delay will enroll with their child (up to 1 parent per child). Both parent and child will participate in one telehealth-supervised session per week and two unsupervised sessions per week. Both parent and child will wear activity trackers on the wrists and waist for 1 week before and 1 week after treatment in order to measure physical activity and sleep. Parents will also complete surveys on quality of life before and after treatment.
Could this study be right for you?
- Medical diagnosis causing motor delay
- Unable to stand independently
- A parent or primary caregiver able to enroll as a participant in the study
- Internet or cellular service to join telehealth sessions
- Live within 100 miles of Ohio State University or willing to travel to the lab for one visit
Age Range
1 - 6 years -
Living Well with Advanced Breast Cancer
Official Title Living Well with Advanced Breast CancerPurpose
The purpose of this study is to understand how patients with advanced breast cancer are using supportive care, what has helped them, what has been hard, and what kind of help they still need. Our goal is to learn from patients and caregivers about met and unmet survivorship care needs, including care that focuses on improving health and well-being of a person living with cancer.
Study participants would be asked to complete a brief survey on their demographics via phone or email. Participants will then complete a one-time interview with our study staff via zoom, phone call, or in person, depending on preference. During the interview, the study team will ask for feedback on patient and caregiver experience and needs regarding support services.
Total study participation is less than 2 hours and can be done remotely.
Could this study be right for you?
- Diagnosed with stage 4 metastatic breast cancer within the past 5 years
- A patient in the Medical Oncology Clinic at Stephanie Spielman Comprehensive Breast Center (SSCBC)
Age Range
18 - 110 years -
Low Dose Tamoxifen with or without Omega-3 Fatty Acids for Breast Cancer Risk Reduction
Official Title Phase 2 Study of Low Dose Tamoxifen +/- High Dose Omega-3 Fatty Acids in Overweight Postmenopausal Women at Increased Risk for Breast CancerPurpose
This study wants to measure the effects of low dose tamoxifen and omega-3 fatty acids (may also be known as fish oil) on a woman's risk of developing breast cancer.
In this study, half of the participants will be asked to take low dose tamoxifen and the other half low dose tamoxifen with omega-3 fatty acids for about six months. Everyone taking part in the study will be watched carefully for any side effects, which may or may not happen. Tissue and blood collection will be a part of the study participation.
This study is looking for volunteers with an above average risk of developing breast cancer. We will enroll up to 66 participants at institutions across the country. The study lasts about eight months.
Could this study be right for you?
- Postmenopausal
- At increased risk of breast cancer, due to genetic mutation, family history, prior DCIS, LCIS, or atypical hyperplasia
- Overweight or obese (BMI ≥ 25 kg/m2)
- Do not have breast implants
- Seen in Stefanie Spielman Comprehensive Breast Cancer Center in Columbus, OH
Age Range
45 - 65 years