Search Studies

Official Title An Examination of Culturally Responsive, Inclusive, and Socially Just Practices Parent Feedback

Purpose

The research study will examine parents’ - or a child’s primary caregiver - perspectives on an online professional development (PD) training for teachers, targeting early care and education (ECE) teachers’ use of culturally responsive, inclusive, and socially just practices. Parents of young children will be recruited to review the online PD course and complete surveys about the course. A subset of participants will participate in a focus group to share their feedback on the course.

Could this study be right for you?

Parent or caregiver to a child who:

- Is between 3 and 5 years old

- Is identified as Black/African American

- Attends a center-based early care and education program (pre-kindergarten, Head Start, child care, preschool, etc.)

Age Range

17 - 99 years

Official Title Visuomotor skills assessed with different sports vision-related devices

Purpose

The purpose of this project is to determine whether performance correlates between different hand-eye coordination testing and training devices. Two of these devices require the participant to push lighted buttons on a wall-mounted board as fast as possible. The other device requires the participant to push a button at the same time that a (simulated) approaching object arrives.

 

Could this study be right for you?

• Visual acuity of 20/20 in each eye
• Stereoacuity (depth perception) of 60 seconds of arc
• No eye turn (strabismus) in left, right, or straight ahead gaze

Age Range

18 - 40 years

Official Title Progression of Social Cognitive Deficits in Mid- and Late-Life Schizophrenia Spectrum Disorders

Purpose

This research is being done to investigate the effects of age on social cognition in schizophrenia spectrum disorder. The study also hopes to examine potential neural bases of social cognition. The findings of the research will help develop effective treatment strategies by identifying who, when, and how to intervene.

Could this study be right for you?

Patients:

• Diagnosis of a schizophrenia spectrum disorder (includes schizophrenia, schizoaffective disorder, bipolar disorder with psychotic features, schizophreniform disorder, unspecified or other-specified psychotic disorders)

Healthy Controls:

• No history of any psychotic disorder
• No psychiatric diagnosis in the last 5 years
• Not taking psychotropic medication 

 

Age Range

35 - 75 years

Official Title A Phase 1, Randomized, Double-Blind, Placebo-Controlled Study Evaluating the Safety, Tolerability, and Pharmacokinetics of Single Escalating Doses of LH-001 in Healthy Subjects

Purpose

The purpose of this study is to evaluate the safety and tolerability of an investigational new drug in healthy participants aged 18-60 years.

Could this study be right for you?

• In good health and BMI (ratio of body weight to height) between 18-26 kg/m2
• Willing to participate in various research assessments including blood collection, urine collection, electrocardiogram, and vital signs
• Willing to stay overnight (~30 hours) in the OSU Hospital Clinical Research Center
• If sexually active, willing to utilize highly effective birth control during the study period
• Not currently pregnant or breast-feeding
• No any significant medical condition involving any major organs (heart, lung, liver, brain, or endocrine)
• No any of the following: cancer, alcohol or substance abuse, spleen problems, or drug hypersensitivity
• No history of or undergoing treatment for: major psychiatric illness, seizures, or autoimmune disease
• Not currently taking immunosuppressive drugs
• No active Hepatitis B, Hepatitis C, or HIV

Age Range

18 - 60 years

Official Title IMPROVE-AD Trial: IMPRoving Outcomes in Vascular DisEase – Aortic Dissection

Purpose

The goal of this study is to figure out the best way to treat type aortic dissection. An aortic dissection is a tear in the wall of the aorta. The aorta is a big blood vessel that carries blood from your heart to the rest of your body. Individuals with this problem usually get medicine or a special repair procedure. This procedure is called thoracic endovascular aortic repair (TEVAR). TEVAR is a procedure where a metal tube (called a stent), is inserted in the damaged part of the aorta. The study is being done to figure out which treatment works better. The results of the study may help to prevent future problems with the aorta or other health issues. 

 

Could this study be right for you?

Inclusion:

• Age > 21 years
• Stanford type B aortic dissection not involving the aorta at or proximal to the innominate artery, without rupture and/or malperfusion (renal, mesenteric, or extremity)
• Acuity: within 48 hours – 6 weeks of index admission

Exclusion criteria:

• Ongoing systemic infection
• Pregnant or planning to become pregnant in the next 3 months
• Life expectancy related to non-aortic conditions < 2 years
• Prior surgery for aortic dissection

Age Range

21 years and up

Official Title AAA-SHAPE Pivotal Trial: Abdominal Aortic Aneurysm Sac Healing and Prevention of Expansion

Purpose

The purpose of this research is to determine if the IMPEDE-FX RapidFill System is safe and helps to shrink abdominal aortic aneurysm (AAA - a bulge or swelling due to weakening of the walls of the aorta, which is the main blood vessel that carries blood from your heart to other parts of your body) sacs after an endovascular stent graft (a fabric tube supported by metal wire stents that reinforces a weakened aorta) has been placed. The IMPEDE-FX RapidFill System used in this study is classified as investigational, which means it has not been approved by the Food and Drug Administration (FDA).

Could this study be right for you?

Inclusion:

• A candidate for elective EVAR of an infrarenal fusiform aortic aneurysm ≥5.5 cm in diameter in men and ≥ 5.0 cm in women 
• Thrombus burden (percentage of the AAA sac occupied by thrombus) <50%, based on pre-procedure CTA
• Maximum Lumen diameter within the AAA sac of ≥40mm
• The predicted minimum number of IMPEDE-FX RapidFill Implants for the subject is ≤200

Exclusion:

• An inability to provide informed consent
• Enrolled in another clinical study that could interfere with the outcomes being studied in this trial
• Unable or unwilling to comply with study follow-up requirements

Inclusion and Exclusion Criteria varies, please contact Study Coordinator for more information. 

Age Range

18 years and up

Official Title Sexual and gender diverse young adults' preferences for nicotine and tobacco product attributes

Purpose

We are inviting LGBTQ+ folks to share their opinions about product features (e.g., flavors, nicotine levels) and other factors (e.g., stress, social media, marketing) that make people want to try or continue to use tobacco products.

Could this study be right for you?

Able to speak English fluently,

identify as LGBTQ+,

used nicotine/tobacco products in past 30-days (cigarettes, cigars, cigarillos, e-cigarettes, etc.), and

reside in the U.S.

Age Range

18 - 34 years

Official Title Testing Equivalence of Measures of Parental Socialization Beliefs and Behaviors Across Racial/Ethnic Groups

Purpose

This study aims to investigate the similarity and differences in parents' beliefs and practices across racial/ethnic backgrounds.

Could this study be right for you?

Eligibility Criteria includes:

- Must be proficient in written English

- You are parents of a child aged 3 to 10, who was born in the U.S.

Age Range

18 - 80 years

Official Title Operating Microscope versus Traditional Loupes during Regeneration Therapy for Peri-implantitis: A Randomized Controlled Trial with Ultrasonographic and Biomarkers Evaluation

Purpose

The purpose of this study is to compare the one-year outcomes of treating peri-implantitis with periodontal surgical means between the use of an Operating Microscope and dental loupes.

This study includes the comparisons of the changes of inflammation of the gums, the bacteria present, and wound healing at the surgical site between the two methods. The hypothesis is that the use of the operating microscope, compared to dental loupes, is associated with better bacteria removal, quicker inflammatory resolution, and improved wound healing, which will contribute to better outcomes.

Could this study be right for you?

Inclusion criteria: Participant has at least one implant indicated for peri-implant regenerative treatment.

Exclusion criteria: Participant has known systemic conditions and medication interactions that can affect healing of the surgical site.

Age Range

18 - 99 years

Official Title The mom and infant outcomes (MOMI) study: A trial of perinatal outpatient delivery systems

Purpose

​To improve our ability to provide the best possible care to every mom and infant, we are testing two different models of primary care during the first year after childbirth.

Could this study be right for you?

- You may qualify if you’re currently pregnant – AND – you’ve ever had high blood pressure, diabetes, depression, or anxiety, including during pregnancy.

- If you participate, you’ll be randomly assigned to an Ohio State location that delivers one of two models of care. Providers at all locations can help you manage your health, but the models differ in several ways.

- You’ll complete three study visits with surveys, several measurements, and blood and hair sampling. We’ll collect cord blood and review medical records. 

Official Title Client and clinician preferences for same-day PrEP and doxy-PEP awareness, uptake and persistence in primary care.

Purpose

The purpose of this study is to better understand the perspectives of both primary care clinicians and the LGBTQ+ clients they serve and how to best improve the awareness and sustained use of available STI and HIV prevention methods to ultimately improve the sexual health disparities among LGBTQ+ populations. 

Could this study be right for you?

• 15 years of age or older
• Speak & read English
• Identify as LGBTQ+ and have ever used primary care
• Primary care provider (MD, DO, APRN, PA, PharmD)
• Have access to the internet

Age Range

15 - 150 years

Official Title Longitudinal Changes in Eye Shape in Young Adults Treated with Low-Dose Atropine and Soft Multifocal Contact Lenses

Purpose

The purpose of this study is to understand how the myopia control treatments (multifocal contact lenses and low-dose atropine) affect the shape of the eye over one year.

Could this study be right for you?

• Nearsighted
• Current contact lens wearer
• No significant ocular disease
• Willingness to be randomized to one of three groups: no intervention, MiSight contact lenses (multifocal contact lenses, instead of current lenses), or daily low-dose atropine eyedrops
• Willingness to attend a study visit every three months for one year (5 total visits)
• Meet other study eligibility criteria

Age Range

21 - 30 years